77 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ctdspl	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like a. (279 aa)
	LOC101471656	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (131 aa)
	brd7	Bromodomain containing 7. (598 aa)
	LOC101474055	ADAM metallopeptidase domain 17a. (861 aa)
	fhl1	Four and a half LIM domains 1a. (296 aa)
	LOC101477921	BH4_2 domain-containing protein. (198 aa)
	LOC101477072	Retinoblastoma-like 2 (p130). (1075 aa)
	ddx59	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1614 aa)
	rgcc	Regulator of cell cycle. (127 aa)
	tm4sf5	Transmembrane 4 L six family member 5. (202 aa)
	e2f1	E2F transcription factor 1. (454 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (164 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	fbxo31	F-box protein 31. (556 aa)
	stox1	Storkhead box 1. (1090 aa)
	plrg1	Pleiotropic regulator 1. (513 aa)
	pkd1	Polycystic kidney disease 1a. (4659 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1062 aa)
	ENSMZEP00005000346	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (556 aa)
	crlf3	Cytokine receptor-like factor 3. (445 aa)
	LOC101470317	P53-induced death domain protein 1. (872 aa)
	LOC101474754	Four and a half LIM domains 1b. (279 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1356 aa)
	ENSMZEP00005003882	PLAT domain-containing protein. (257 aa)
	ecd	Ecdysoneless homolog (Drosophila). (721 aa)
	ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2. (267 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	mtbp	MDM2 binding protein. (869 aa)
	cdc73	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (671 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (863 aa)
	bcl7a	BAF chromatin remodeling complex subunit BCL7A. (199 aa)
	LOC101468451	WW domain-containing protein. (524 aa)
	e2f7	E2F transcription factor 7. (790 aa)
	lsm11	LSM11, U7 small nuclear RNA associated. (334 aa)
	appl2	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (666 aa)
	gpnmb	Glycoprotein (transmembrane) nmb. (634 aa)
	prmt2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (418 aa)
	mblac1	Metallo-beta-lactamase domain containing 1. (220 aa)
	dcun1d3	DCN1-like protein. (326 aa)
	prkdc	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4055 aa)
	LOC101470658	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b. (325 aa)
	psme1	Proteasome activator subunit 1. (255 aa)
	rptor	Regulatory associated protein of MTOR, complex 1. (1350 aa)
	LOC101466273	Uncharacterized protein. (178 aa)
	ino80	INO80 complex ATPase subunit. (1506 aa)
	AIF1	Allograft inflammatory factor 1. (146 aa)
	ENSMZEP00005018676	Uncharacterized protein. (143 aa)
	LOC101477206	ADAM metallopeptidase domain 17b. (827 aa)
	LOC101469767	Cleavage and polyadenylation specific factor 3. (686 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (331 aa)
	rfwd3	Ring finger and WD repeat domain 3. (707 aa)
	LOC101475966	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1. (247 aa)
	rb1	Retinoblastoma 1. (912 aa)
	appl1	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (708 aa)
	LOC101465314	Uncharacterized protein. (193 aa)
	LOC101464645	Si:ch211-137i24.10. (191 aa)
	LOC101465796	Si:ch211-137i24.10. (191 aa)
	wac	WW domain containing adaptor with coiled-coil a. (543 aa)
	LOC101472403	Cyclin D2, a; Belongs to the cyclin family. (297 aa)
	ccnd1	Cyclin D1; Belongs to the cyclin family. (292 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (464 aa)
	CTDSP1	CTD small phosphatase 1. (262 aa)
	stil	STIL centriolar assembly protein. (1072 aa)
	LOC101486360	Uncharacterized protein. (205 aa)
	sass6	SAS-6 centriolar assembly protein. (588 aa)
	pla2g4a	Phospholipase A2. (745 aa)
	fbxo7	F-box protein 7. (489 aa)
	kank2	KN motif and ankyrin repeat domains 2. (1027 aa)
	kmt2e	Lysine (K)-specific methyltransferase 2E. (1232 aa)
	LOC101485787	Cullin 4A; Belongs to the cullin family. (742 aa)
	LOC101479984	Cyclin D2, b; Belongs to the cyclin family. (294 aa)
	ENSMZEP00005005823	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (163 aa)
	id2	Inhibitor of DNA binding 2a. (136 aa)
	ENSMZEP00005007743	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4). (168 aa)
	CPSF3	Cleavage and polyadenylation specific factor 3. (690 aa)
	psme2	Proteasome activator subunit 2. (245 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CPSF3	LOC101469767	ENSMZEP00005008256	ENSMZEP00005019140	Cleavage and polyadenylation specific factor 3.	Cleavage and polyadenylation specific factor 3.	0.900
CPSF3	LSM10	ENSMZEP00005008256	ENSMZEP00005035193	Cleavage and polyadenylation specific factor 3.	LSM10, U7 small nuclear RNA associated.	0.852
CPSF3	cdc73	ENSMZEP00005008256	ENSMZEP00005009998	Cleavage and polyadenylation specific factor 3.	Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae).	0.442
CPSF3	lsm11	ENSMZEP00005008256	ENSMZEP00005011670	Cleavage and polyadenylation specific factor 3.	LSM11, U7 small nuclear RNA associated.	0.545
CPSF3	prkdc	ENSMZEP00005008256	ENSMZEP00005015388	Cleavage and polyadenylation specific factor 3.	Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.	0.474
CTDSP1	ccnh	ENSMZEP00005023401	ENSMZEP00005019333	CTD small phosphatase 1.	Cyclin H; Belongs to the cyclin family.	0.491
CTDSP1	mnat1	ENSMZEP00005023401	ENSMZEP00005009823	CTD small phosphatase 1.	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.	0.479
ENSMZEP00005005823	ENSMZEP00005018676	ENSMZEP00005005823	ENSMZEP00005018676	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Uncharacterized protein.	0.412
ENSMZEP00005005823	LOC101466273	ENSMZEP00005005823	ENSMZEP00005016186	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Uncharacterized protein.	0.432
ENSMZEP00005005823	LOC101472403	ENSMZEP00005005823	ENSMZEP00005021921	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D2, a; Belongs to the cyclin family.	0.568
ENSMZEP00005005823	LOC101479984	ENSMZEP00005005823	ENSMZEP00005004269	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D2, b; Belongs to the cyclin family.	0.568
ENSMZEP00005005823	ccnd1	ENSMZEP00005005823	ENSMZEP00005023010	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D1; Belongs to the cyclin family.	0.568
ENSMZEP00005007743	ENSMZEP00005018676	ENSMZEP00005007743	ENSMZEP00005018676	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Uncharacterized protein.	0.412
ENSMZEP00005007743	LOC101466273	ENSMZEP00005007743	ENSMZEP00005016186	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Uncharacterized protein.	0.432
ENSMZEP00005007743	LOC101472403	ENSMZEP00005007743	ENSMZEP00005021921	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D2, a; Belongs to the cyclin family.	0.955
ENSMZEP00005007743	LOC101479984	ENSMZEP00005007743	ENSMZEP00005004269	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D2, b; Belongs to the cyclin family.	0.955
ENSMZEP00005007743	ccnd1	ENSMZEP00005007743	ENSMZEP00005023010	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	Cyclin D1; Belongs to the cyclin family.	0.955
ENSMZEP00005018676	ENSMZEP00005005823	ENSMZEP00005018676	ENSMZEP00005005823	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	0.412
ENSMZEP00005018676	ENSMZEP00005007743	ENSMZEP00005018676	ENSMZEP00005007743	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).	0.412
ENSMZEP00005018676	LOC101471656	ENSMZEP00005018676	ENSMZEP00005026477	Uncharacterized protein.	Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).	0.543