(15 nodes) Proteasome accessory complex network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	psmd1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
	psmd7	Proteasome 26S subunit, non-ATPase 7. (330 aa)
	psmd3	Proteasome 26S subunit, non-ATPase 3. (522 aa)
	psmd2	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (906 aa)
	psmd5	Proteasome 26S subunit, non-ATPase 5. (504 aa)
	psmd12	Proteasome 26S subunit, non-ATPase 12. (456 aa)
	psme2	Proteasome activator subunit 2. (245 aa)
	psmd8	Proteasome 26S subunit, non-ATPase 8. (265 aa)
	LOC101479706	Proteasome 26S subunit, non-ATPase 4a. (372 aa)
	psmd13	Proteasome 26S subunit, non-ATPase 13. (379 aa)
	psme3	Proteasome activator subunit 3. (256 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	psme1	Proteasome activator subunit 1. (255 aa)
	sem1	SEM1 26S proteasome complex subunit. (70 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101479706	psmc1	ENSMZEP00005035592	ENSMZEP00005008135	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.996
LOC101479706	psmc6	ENSMZEP00005035592	ENSMZEP00005019690	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.989
LOC101479706	psmd1	ENSMZEP00005035592	ENSMZEP00005023691	Proteasome 26S subunit, non-ATPase 4a.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.988
LOC101479706	psmd12	ENSMZEP00005035592	ENSMZEP00005002522	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 12.	0.995
LOC101479706	psmd13	ENSMZEP00005035592	ENSMZEP00005021997	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 13.	0.995
LOC101479706	psmd2	ENSMZEP00005035592	ENSMZEP00005004544	Proteasome 26S subunit, non-ATPase 4a.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.992
LOC101479706	psmd3	ENSMZEP00005035592	ENSMZEP00005006245	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 3.	0.991
LOC101479706	psmd5	ENSMZEP00005035592	ENSMZEP00005003063	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 5.	0.971
LOC101479706	psmd7	ENSMZEP00005035592	ENSMZEP00005025907	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 7.	0.994
LOC101479706	psmd8	ENSMZEP00005035592	ENSMZEP00005032430	Proteasome 26S subunit, non-ATPase 4a.	Proteasome 26S subunit, non-ATPase 8.	0.994
LOC101479706	psme1	ENSMZEP00005035592	ENSMZEP00005015955	Proteasome 26S subunit, non-ATPase 4a.	Proteasome activator subunit 1.	0.516
LOC101479706	psme2	ENSMZEP00005035592	ENSMZEP00005026215	Proteasome 26S subunit, non-ATPase 4a.	Proteasome activator subunit 2.	0.468
LOC101479706	psme3	ENSMZEP00005035592	ENSMZEP00005009703	Proteasome 26S subunit, non-ATPase 4a.	Proteasome activator subunit 3.	0.577
LOC101479706	sem1	ENSMZEP00005035592	ENSMZEP00005011901	Proteasome 26S subunit, non-ATPase 4a.	SEM1 26S proteasome complex subunit.	0.948
psmc1	LOC101479706	ENSMZEP00005008135	ENSMZEP00005035592	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 4a.	0.996
psmc1	psmc6	ENSMZEP00005008135	ENSMZEP00005019690	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family.	0.999
psmc1	psmd1	ENSMZEP00005008135	ENSMZEP00005023691	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.	0.999
psmc1	psmd12	ENSMZEP00005008135	ENSMZEP00005002522	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 12.	0.999
psmc1	psmd13	ENSMZEP00005008135	ENSMZEP00005021997	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	Proteasome 26S subunit, non-ATPase 13.	0.999
psmc1	psmd2	ENSMZEP00005008135	ENSMZEP00005004544	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.999