(25 nodes) COPI-coated vesicle membrane network (Maylandia zebra)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101484380	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (215 aa)
	ENSMZEP00005031012	Proline rich 15 like a. (108 aa)
	copa	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1222 aa)
	ENSMZEP00005034227	WD_REPEATS_REGION domain-containing protein. (391 aa)
	ENSMZEP00005034230	WD_REPEATS_REGION domain-containing protein. (109 aa)
	ENSMZEP00005029731	WD_REPEATS_REGION domain-containing protein. (156 aa)
	dipk2a	Divergent protein kinase domain 2Ab. (434 aa)
	copb1	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (953 aa)
	LOC101467832	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (930 aa)
	cope	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family. (302 aa)
	LOC101465491	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (511 aa)
	kdelr3	KDEL endoplasmic reticulum protein retention receptor 3. (261 aa)
	LOC101481674	ER lumen protein-retaining receptor. (212 aa)
	LOC101482677	ER lumen protein-retaining receptor. (212 aa)
	LOC101473720	F-box and WD repeat domain containing 10. (768 aa)
	COPB2	WD_REPEATS_REGION domain-containing protein. (1203 aa)
	LOC112435889	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (475 aa)
	ENSMZEP00005012894	Uncharacterized protein. (358 aa)
	copg2	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (873 aa)
	LOC101483881	Proline rich 15 like b. (166 aa)
	fbxw7	F-box and WD repeat domain containing 7. (773 aa)
	ENSMZEP00005037953	WD_REPEATS_REGION domain-containing protein. (82 aa)
	copz1	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (177 aa)
	ENSMZEP00005012828	WD_REPEATS_REGION domain-containing protein. (295 aa)
	ENSMZEP00005010699	Proline rich 15 like b. (107 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COPB2	ENSMZEP00005010699	ENSMZEP00005006420	ENSMZEP00005010699	WD_REPEATS_REGION domain-containing protein.	Proline rich 15 like b.	0.841
COPB2	ENSMZEP00005031012	ENSMZEP00005006420	ENSMZEP00005031012	WD_REPEATS_REGION domain-containing protein.	Proline rich 15 like a.	0.841
COPB2	LOC101465491	ENSMZEP00005006420	ENSMZEP00005027750	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.975
COPB2	LOC101481674	ENSMZEP00005006420	ENSMZEP00005005114	WD_REPEATS_REGION domain-containing protein.	ER lumen protein-retaining receptor.	0.648
COPB2	LOC101482677	ENSMZEP00005006420	ENSMZEP00005004560	WD_REPEATS_REGION domain-containing protein.	ER lumen protein-retaining receptor.	0.648
COPB2	LOC101483881	ENSMZEP00005006420	ENSMZEP00005010671	WD_REPEATS_REGION domain-containing protein.	Proline rich 15 like b.	0.841
COPB2	LOC101484380	ENSMZEP00005006420	ENSMZEP00005031004	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.841
COPB2	LOC112435889	ENSMZEP00005006420	ENSMZEP00005026020	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.975
COPB2	copa	ENSMZEP00005006420	ENSMZEP00005032438	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.	0.993
COPB2	copb1	ENSMZEP00005006420	ENSMZEP00005000210	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.997
COPB2	cope	ENSMZEP00005006420	ENSMZEP00005004210	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit epsilon; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Belongs to the COPE family.	0.982
COPB2	copg2	ENSMZEP00005006420	ENSMZEP00005008878	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.989
COPB2	copz1	ENSMZEP00005006420	ENSMZEP00005036406	WD_REPEATS_REGION domain-containing protein.	Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.	0.868
COPB2	kdelr3	ENSMZEP00005006420	ENSMZEP00005007070	WD_REPEATS_REGION domain-containing protein.	KDEL endoplasmic reticulum protein retention receptor 3.	0.648
ENSMZEP00005010699	COPB2	ENSMZEP00005010699	ENSMZEP00005006420	Proline rich 15 like b.	WD_REPEATS_REGION domain-containing protein.	0.841
ENSMZEP00005010699	LOC101465491	ENSMZEP00005010699	ENSMZEP00005027750	Proline rich 15 like b.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.852
ENSMZEP00005010699	LOC101467832	ENSMZEP00005010699	ENSMZEP00005003716	Proline rich 15 like b.	Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.841
ENSMZEP00005010699	LOC101481674	ENSMZEP00005010699	ENSMZEP00005005114	Proline rich 15 like b.	ER lumen protein-retaining receptor.	0.584
ENSMZEP00005010699	LOC101482677	ENSMZEP00005010699	ENSMZEP00005004560	Proline rich 15 like b.	ER lumen protein-retaining receptor.	0.584
ENSMZEP00005010699	LOC112435889	ENSMZEP00005010699	ENSMZEP00005026020	Proline rich 15 like b.	Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.852