(15 nodes) Beta-catenin destruction complex network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	gsk3b	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)
	LOC101472422	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
	cacybp	Calcyclin binding protein. (227 aa)
	Apc	APC_N_CC domain-containing protein. (220 aa)
	axin1	Axin 1. (825 aa)
	ENSMZEP00005028107	annotation not available (289 aa)
	ENSMZEP00005028104	ANK_REP_REGION domain-containing protein. (258 aa)
	LOC101487071	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (440 aa)
	LOC101472703	Uncharacterized protein. (883 aa)
	ctnnbip1	Catenin, beta interacting protein 1. (81 aa)
	AXIN2	Axin 2. (793 aa)
	ENSMZEP00005005760	Ankyrin repeat domain 6b. (286 aa)
	ENSMZEP00005005730	Uncharacterized protein. (289 aa)
	LOC101464051	Axin 2 (conductin, axil). (841 aa)
	apc2	APC regulator of WNT signaling pathway 2. (2516 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	Apc	ENSMZEP00005015032	ENSMZEP00005031072	Axin 2.	APC_N_CC domain-containing protein.	0.984
AXIN2	LOC101472422	ENSMZEP00005015032	ENSMZEP00005034787	Axin 2.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.824
AXIN2	LOC101487071	ENSMZEP00005015032	ENSMZEP00005024692	Axin 2.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.824
AXIN2	apc2	ENSMZEP00005015032	ENSMZEP00005003894	Axin 2.	APC regulator of WNT signaling pathway 2.	0.984
AXIN2	gsk3b	ENSMZEP00005015032	ENSMZEP00005001821	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.985
Apc	AXIN2	ENSMZEP00005031072	ENSMZEP00005015032	APC_N_CC domain-containing protein.	Axin 2.	0.984
Apc	LOC101464051	ENSMZEP00005031072	ENSMZEP00005004394	APC_N_CC domain-containing protein.	Axin 2 (conductin, axil).	0.984
Apc	LOC101472422	ENSMZEP00005031072	ENSMZEP00005034787	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.	0.847
Apc	LOC101472703	ENSMZEP00005031072	ENSMZEP00005018244	APC_N_CC domain-containing protein.	Uncharacterized protein.	0.984
Apc	LOC101487071	ENSMZEP00005031072	ENSMZEP00005024692	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.	0.847
Apc	apc2	ENSMZEP00005031072	ENSMZEP00005003894	APC_N_CC domain-containing protein.	APC regulator of WNT signaling pathway 2.	0.900
Apc	axin1	ENSMZEP00005031072	ENSMZEP00005030195	APC_N_CC domain-containing protein.	Axin 1.	0.984
Apc	ctnnbip1	ENSMZEP00005031072	ENSMZEP00005017815	APC_N_CC domain-containing protein.	Catenin, beta interacting protein 1.	0.733
Apc	gsk3b	ENSMZEP00005031072	ENSMZEP00005001821	APC_N_CC domain-containing protein.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.847
ENSMZEP00005005730	ENSMZEP00005005760	ENSMZEP00005005730	ENSMZEP00005005760	Uncharacterized protein.	Ankyrin repeat domain 6b.	0.894
ENSMZEP00005005730	ENSMZEP00005028104	ENSMZEP00005005730	ENSMZEP00005028104	Uncharacterized protein.	ANK_REP_REGION domain-containing protein.	0.892
ENSMZEP00005005760	ENSMZEP00005005730	ENSMZEP00005005760	ENSMZEP00005005730	Ankyrin repeat domain 6b.	Uncharacterized protein.	0.894
ENSMZEP00005005760	ENSMZEP00005028107	ENSMZEP00005005760	ENSMZEP00005028107	Ankyrin repeat domain 6b.	annotation not available	0.894
ENSMZEP00005028104	ENSMZEP00005005730	ENSMZEP00005028104	ENSMZEP00005005730	ANK_REP_REGION domain-containing protein.	Uncharacterized protein.	0.892
ENSMZEP00005028104	ENSMZEP00005028107	ENSMZEP00005028104	ENSMZEP00005028107	ANK_REP_REGION domain-containing protein.	annotation not available	0.892