(24 nodes) Double-stranded RNA-binding domain network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	adarb1	Uncharacterized protein. (729 aa)
	dus2	Dihydrouridine synthase 2. (498 aa)
	ilf3	Interleukin enhancer binding factor 3b. (847 aa)
	adad1	Adenosine deaminase domain containing 1 (testis-specific). (559 aa)
	prkra	Protein kinase, interferon-inducible double stranded RNA dependent activator. (290 aa)
	tarbp2	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (345 aa)
	ADARB2	Uncharacterized protein. (726 aa)
	nkrf	NFKB repressing factor. (799 aa)
	LOC101480895	Uncharacterized protein. (867 aa)
	LOC101483299	Uncharacterized protein. (676 aa)
	stau2	Staufen double-stranded RNA binding protein 2. (667 aa)
	LOC101480319	Uncharacterized protein. (600 aa)
	LOC101480601	Eukaryotic translation initiation factor 2-alpha kinase 2. (649 aa)
	LOC101478147	Interleukin enhancer binding factor 3a. (864 aa)
	dhx9	DEAH (Asp-Glu-Ala-His) box helicase 9. (1271 aa)
	stau1	Staufen double-stranded RNA binding protein 1. (691 aa)
	adar	Adenosine deaminase RNA specific. (1344 aa)
	dicer1	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily. (1906 aa)
	LOC101485294	Adenosine deaminase RNA specific B1b. (747 aa)
	LOC101472103	Adenosine deaminase RNA specific B2 (inactive). (754 aa)
	strbp	Spermatid perinuclear RNA binding protein. (734 aa)
	dgcr8	DGCR8 microprocessor complex subunit. (782 aa)
	LOC101470950	Uncharacterized protein. (936 aa)
	drosha	Drosha ribonuclease III. (1362 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101480319	LOC101480895	ENSMZEP00005013033	ENSMZEP00005012972	Uncharacterized protein.	Uncharacterized protein.	0.904
LOC101480319	adar	ENSMZEP00005013033	ENSMZEP00005021024	Uncharacterized protein.	Adenosine deaminase RNA specific.	0.520
LOC101480319	dhx9	ENSMZEP00005013033	ENSMZEP00005018878	Uncharacterized protein.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.420
LOC101480319	dicer1	ENSMZEP00005013033	ENSMZEP00005022701	Uncharacterized protein.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.414
LOC101480319	ilf3	ENSMZEP00005013033	ENSMZEP00005003084	Uncharacterized protein.	Interleukin enhancer binding factor 3b.	0.655
LOC101480319	prkra	ENSMZEP00005013033	ENSMZEP00005005765	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.499
LOC101480319	tarbp2	ENSMZEP00005013033	ENSMZEP00005009080	Uncharacterized protein.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.499
LOC101480601	adar	ENSMZEP00005013093	ENSMZEP00005021024	Eukaryotic translation initiation factor 2-alpha kinase 2.	Adenosine deaminase RNA specific.	0.520
LOC101480601	dhx9	ENSMZEP00005013093	ENSMZEP00005018878	Eukaryotic translation initiation factor 2-alpha kinase 2.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.420
LOC101480601	dicer1	ENSMZEP00005013093	ENSMZEP00005022701	Eukaryotic translation initiation factor 2-alpha kinase 2.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.414
LOC101480601	ilf3	ENSMZEP00005013093	ENSMZEP00005003084	Eukaryotic translation initiation factor 2-alpha kinase 2.	Interleukin enhancer binding factor 3b.	0.655
LOC101480601	prkra	ENSMZEP00005013093	ENSMZEP00005005765	Eukaryotic translation initiation factor 2-alpha kinase 2.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.499
LOC101480601	tarbp2	ENSMZEP00005013093	ENSMZEP00005009080	Eukaryotic translation initiation factor 2-alpha kinase 2.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.499
LOC101480895	LOC101480319	ENSMZEP00005012972	ENSMZEP00005013033	Uncharacterized protein.	Uncharacterized protein.	0.904
LOC101480895	adar	ENSMZEP00005012972	ENSMZEP00005021024	Uncharacterized protein.	Adenosine deaminase RNA specific.	0.520
LOC101480895	dhx9	ENSMZEP00005012972	ENSMZEP00005018878	Uncharacterized protein.	DEAH (Asp-Glu-Ala-His) box helicase 9.	0.420
LOC101480895	dicer1	ENSMZEP00005012972	ENSMZEP00005022701	Uncharacterized protein.	Dicer 1, ribonuclease type III; Belongs to the helicase family. Dicer subfamily.	0.414
LOC101480895	ilf3	ENSMZEP00005012972	ENSMZEP00005003084	Uncharacterized protein.	Interleukin enhancer binding factor 3b.	0.655
LOC101480895	prkra	ENSMZEP00005012972	ENSMZEP00005005765	Uncharacterized protein.	Protein kinase, interferon-inducible double stranded RNA dependent activator.	0.499
LOC101480895	tarbp2	ENSMZEP00005012972	ENSMZEP00005009080	Uncharacterized protein.	RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]	0.499