(29 nodes) Chromo domain network (Maylandia zebra)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101486998	Chromobox homolog 2 (Drosophila Pc class). (526 aa)
	chd5	Chromodomain helicase DNA binding protein 5. (1797 aa)
	LOC101484948	Chromodomain helicase DNA binding protein 4a. (1954 aa)
	LOC101467917	Chromobox homolog 8a (Pc class homolog, Drosophila). (342 aa)
	LOC101467610	Chromobox homolog 4 (Pc class homolog, Drosophila). (616 aa)
	LOC101477848	Chromobox homolog 7a. (357 aa)
	ENSMZEP00005007240	Chromo domain-containing protein. (745 aa)
	chd9	Chromodomain helicase DNA binding protein 9. (3007 aa)
	ENSMZEP00005008823	Chromo domain-containing protein. (508 aa)
	CBX1	Chromobox homolog 1b (HP1 beta homolog Drosophila). (200 aa)
	cbx3	Chromobox homolog 3a (HP1 gamma homolog, Drosophila). (192 aa)
	chd7	Chromodomain helicase DNA binding protein 7. (3316 aa)
	chd1	Chromodomain helicase DNA binding protein 1. (1326 aa)
	LOC101477503	Chromobox 4. (647 aa)
	cbx8	Chromobox homolog 8b. (361 aa)
	chd8	Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2521 aa)
	CDYL2	Chromodomain Y like 2. (511 aa)
	CBX2	Chromobox 2. (541 aa)
	LOC101483327	Chromobox homolog 3b. (192 aa)
	ENSMZEP00005022380	Chromo domain-containing protein. (486 aa)
	chd4	Uncharacterized protein. (1813 aa)
	suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (398 aa)
	mphosph8	Chromo domain-containing protein. (1794 aa)
	cdyl	Chromodomain protein, Y-like. (558 aa)
	chd3	Chromodomain helicase DNA binding protein 3. (2127 aa)
	chd2	Chromodomain helicase DNA binding protein 2. (1700 aa)
	CBX1-2	Uncharacterized protein. (213 aa)
	cbx5	Chromobox homolog 5 (HP1 alpha homolog, Drosophila). (199 aa)
	cbx7	Chromobox homolog 7b. (258 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX1	LOC101484948	ENSMZEP00005010791	ENSMZEP00005002283	Chromobox homolog 1b (HP1 beta homolog Drosophila).	Chromodomain helicase DNA binding protein 4a.	0.612
CBX1	chd3	ENSMZEP00005010791	ENSMZEP00005028531	Chromobox homolog 1b (HP1 beta homolog Drosophila).	Chromodomain helicase DNA binding protein 3.	0.612
CBX1	chd4	ENSMZEP00005010791	ENSMZEP00005023746	Chromobox homolog 1b (HP1 beta homolog Drosophila).	Uncharacterized protein.	0.612
CBX1	chd5	ENSMZEP00005010791	ENSMZEP00005001102	Chromobox homolog 1b (HP1 beta homolog Drosophila).	Chromodomain helicase DNA binding protein 5.	0.612
CBX1	suv39h1	ENSMZEP00005010791	ENSMZEP00005024813	Chromobox homolog 1b (HP1 beta homolog Drosophila).	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.875
CBX1-2	LOC101484948	ENSMZEP00005030979	ENSMZEP00005002283	Uncharacterized protein.	Chromodomain helicase DNA binding protein 4a.	0.612
CBX1-2	chd3	ENSMZEP00005030979	ENSMZEP00005028531	Uncharacterized protein.	Chromodomain helicase DNA binding protein 3.	0.612
CBX1-2	chd4	ENSMZEP00005030979	ENSMZEP00005023746	Uncharacterized protein.	Uncharacterized protein.	0.612
CBX1-2	chd5	ENSMZEP00005030979	ENSMZEP00005001102	Uncharacterized protein.	Chromodomain helicase DNA binding protein 5.	0.612
CBX1-2	suv39h1	ENSMZEP00005030979	ENSMZEP00005024813	Uncharacterized protein.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.	0.875
CBX2	ENSMZEP00005008823	ENSMZEP00005017266	ENSMZEP00005008823	Chromobox 2.	Chromo domain-containing protein.	0.677
CBX2	LOC101467610	ENSMZEP00005017266	ENSMZEP00005003974	Chromobox 2.	Chromobox homolog 4 (Pc class homolog, Drosophila).	0.774
CBX2	LOC101467917	ENSMZEP00005017266	ENSMZEP00005003960	Chromobox 2.	Chromobox homolog 8a (Pc class homolog, Drosophila).	0.738
CBX2	LOC101477503	ENSMZEP00005017266	ENSMZEP00005015559	Chromobox 2.	Chromobox 4.	0.774
CBX2	LOC101477848	ENSMZEP00005017266	ENSMZEP00005004708	Chromobox 2.	Chromobox homolog 7a.	0.556
CBX2	cbx7	ENSMZEP00005017266	ENSMZEP00005037644	Chromobox 2.	Chromobox homolog 7b.	0.556
CBX2	cbx8	ENSMZEP00005017266	ENSMZEP00005015569	Chromobox 2.	Chromobox homolog 8b.	0.738
CDYL2	ENSMZEP00005022380	ENSMZEP00005016352	ENSMZEP00005022380	Chromodomain Y like 2.	Chromo domain-containing protein.	0.416
CDYL2	LOC101484948	ENSMZEP00005016352	ENSMZEP00005002283	Chromodomain Y like 2.	Chromodomain helicase DNA binding protein 4a.	0.485
CDYL2	cdyl	ENSMZEP00005016352	ENSMZEP00005026105	Chromodomain Y like 2.	Chromodomain protein, Y-like.	0.627