54 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	itga1	Integrin, alpha 1; Belongs to the integrin alpha chain family. (1186 aa)
	lpxn	Leupaxin. (392 aa)
	LOC101487074	Phosphodiesterase. (820 aa)
	LOC101470454	Uncharacterized protein; Belongs to the tropomyosin family. (355 aa)
	tpm4	Tropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
	LOC101469963	Talin 2a. (2540 aa)
	LOC101474253	Talin 1. (2501 aa)
	LOC101473166	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	LOC101468518	Myoferlin. (1989 aa)
	anxa6	Annexin. (660 aa)
	myh11	Myosin, heavy chain 11a, smooth muscle; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1964 aa)
	LOC101480470	Myosin, light chain 7, regulatory. (207 aa)
	ENSMZEP00005014401	Uncharacterized protein. (167 aa)
	LOC101472571	Sorbin and SH3 domain containing 1. (936 aa)
	LOC101486181	Sorbin and SH3 domain containing 3. (619 aa)
	gucy1a1	Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (678 aa)
	gucy1b1	Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (611 aa)
	LOC101470913	Myosin light chain, phosphorylatable, fast skeletal muscle a. (170 aa)
	LOC101474423	Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
	ENSMZEP00005034956	Uncharacterized protein. (284 aa)
	pak1	Non-specific serine/threonine protein kinase. (583 aa)
	LOC101481805	Uncharacterized protein. (817 aa)
	LOC101472471	Uncharacterized protein. (522 aa)
	LOC101476290	Uncharacterized protein. (172 aa)
	LOC101479581	Myocardial zonula adherens protein. (673 aa)
	tln2	Talin 2b. (2543 aa)
	LOC101473299	Myosin, light chain 9b, regulatory. (173 aa)
	LOC101480989	Myosin, light chain 6, alkali, smooth muscle and non-muscle. (175 aa)
	LOC101468575	Myoferlin like. (1925 aa)
	tlnrd1	Talin rod domain containing 1. (354 aa)
	TPM1	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	rnf222	RING-type domain-containing protein. (212 aa)
	ENSMZEP00005029124	RING-type domain-containing protein. (182 aa)
	itgb5	Integrin beta; Belongs to the integrin beta chain family. (774 aa)
	ENSMZEP00005026862	Uncharacterized protein. (160 aa)
	pak2	Non-specific serine/threonine protein kinase. (529 aa)
	LOC101481732	Uncharacterized protein; Belongs to the tropomyosin family. (249 aa)
	dysf	Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive). (2053 aa)
	LOC101475765	Paxillin b. (773 aa)
	LOC101475874	Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
	PAK3	Non-specific serine/threonine protein kinase. (634 aa)
	LOC101476955	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (705 aa)
	LOC101469008	Vinculin b. (1066 aa)
	LOC101482131	Myosin light chain, phosphorylatable, fast skeletal muscle b. (170 aa)
	TGFB1I1	Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (479 aa)
	GUCY1A2	Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (801 aa)
	PAK2	Non-specific serine/threonine protein kinase. (513 aa)
	LOC101487661	Vinculin a. (1126 aa)
	LOC101466604	Leiomodin 1b (smooth muscle). (663 aa)
	LOC101479888	Myosin, light chain kinase a. (1073 aa)
	sorbs2	Uncharacterized protein. (1584 aa)
	LOC101481329	Uncharacterized protein. (176 aa)
	MYL12B	Myosin light chain 12B. (172 aa)
	LOC101483695	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1711 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSMZEP00005014401	ENSMZEP00005034956	ENSMZEP00005014401	ENSMZEP00005034956	Uncharacterized protein.	Uncharacterized protein.	0.533
ENSMZEP00005014401	LOC101466604	ENSMZEP00005014401	ENSMZEP00005007268	Uncharacterized protein.	Leiomodin 1b (smooth muscle).	0.473
ENSMZEP00005014401	LOC101469008	ENSMZEP00005014401	ENSMZEP00005021274	Uncharacterized protein.	Vinculin b.	0.497
ENSMZEP00005014401	LOC101469963	ENSMZEP00005014401	ENSMZEP00005012324	Uncharacterized protein.	Talin 2a.	0.434
ENSMZEP00005014401	LOC101470454	ENSMZEP00005014401	ENSMZEP00005012164	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.533
ENSMZEP00005014401	LOC101470913	ENSMZEP00005014401	ENSMZEP00005031061	Uncharacterized protein.	Myosin light chain, phosphorylatable, fast skeletal muscle a.	0.422
ENSMZEP00005014401	LOC101472571	ENSMZEP00005014401	ENSMZEP00005015434	Uncharacterized protein.	Sorbin and SH3 domain containing 1.	0.404
ENSMZEP00005014401	LOC101473166	ENSMZEP00005014401	ENSMZEP00005012476	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.533
ENSMZEP00005014401	LOC101474253	ENSMZEP00005014401	ENSMZEP00005012453	Uncharacterized protein.	Talin 1.	0.434
ENSMZEP00005014401	LOC101474423	ENSMZEP00005014401	ENSMZEP00005032771	Uncharacterized protein.	Tropomyosin 4; Belongs to the tropomyosin family.	0.533
ENSMZEP00005014401	LOC101475765	ENSMZEP00005014401	ENSMZEP00005025236	Uncharacterized protein.	Paxillin b.	0.536
ENSMZEP00005014401	LOC101475874	ENSMZEP00005014401	ENSMZEP00005023318	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.533
ENSMZEP00005014401	LOC101479581	ENSMZEP00005014401	ENSMZEP00005018318	Uncharacterized protein.	Myocardial zonula adherens protein.	0.483
ENSMZEP00005014401	LOC101480989	ENSMZEP00005014401	ENSMZEP00005036478	Uncharacterized protein.	Myosin, light chain 6, alkali, smooth muscle and non-muscle.	0.841
ENSMZEP00005014401	LOC101481329	ENSMZEP00005014401	ENSMZEP00005010863	Uncharacterized protein.	Uncharacterized protein.	0.841
ENSMZEP00005014401	LOC101481732	ENSMZEP00005014401	ENSMZEP00005026513	Uncharacterized protein.	Uncharacterized protein; Belongs to the tropomyosin family.	0.533
ENSMZEP00005014401	LOC101481805	ENSMZEP00005014401	ENSMZEP00005036056	Uncharacterized protein.	Uncharacterized protein.	0.536
ENSMZEP00005014401	LOC101482131	ENSMZEP00005014401	ENSMZEP00005019179	Uncharacterized protein.	Myosin light chain, phosphorylatable, fast skeletal muscle b.	0.422
ENSMZEP00005014401	LOC101483695	ENSMZEP00005014401	ENSMZEP00005001185	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.540
ENSMZEP00005014401	LOC101486181	ENSMZEP00005014401	ENSMZEP00005015467	Uncharacterized protein.	Sorbin and SH3 domain containing 3.	0.404