44 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2516 aa)
	ENSMZEP00005037752	Uncharacterized protein. (328 aa)
	LOC101476427	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
	ENSMZEP00005036083	Uncharacterized protein. (149 aa)
	LOC101472476	Ring finger protein 34b. (420 aa)
	LOC101483949	Death-domain associated protein. (732 aa)
	ccna1	Cyclin A1; Belongs to the cyclin family. (398 aa)
	LOC101466452	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	ENSMZEP00005031506	Protein kinase domain-containing protein. (424 aa)
	ENSMZEP00005030451	Uncharacterized protein. (62 aa)
	cdk2	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	LOC101480650	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (359 aa)
	mdm2	MDM2 proto-oncogene. (523 aa)
	chek2	Checkpoint kinase 2. (490 aa)
	kxd1	KxDL motif containing 1. (192 aa)
	ENSMZEP00005024739	Protein kinase domain-containing protein. (96 aa)
	ENSMZEP00005024733	Protein kinase domain-containing protein. (103 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (595 aa)
	SGK1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
	txndc11	Thioredoxin domain containing 11. (858 aa)
	LOC101480630	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	Atm	Uncharacterized protein. (139 aa)
	ENSMZEP00005016530	TAN domain-containing protein. (177 aa)
	LOC101487597	Serine/threonine-protein phosphatase. (309 aa)
	ccng1	Cyclin G1; Belongs to the cyclin family. (299 aa)
	mapkap1	MAPK associated protein 1. (529 aa)
	pdpk1	3-phosphoinositide dependent protein kinase 1b. (565 aa)
	LOC101469733	Ubiquitin carboxyl-terminal hydrolase. (414 aa)
	rictor	RPTOR independent companion of MTOR, complex 2 a. (1724 aa)
	phf20	PHD finger protein 20, a. (1003 aa)
	rnf34	Ring finger protein 34a. (378 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	LOC101468867	Uncharacterized protein. (477 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (326 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1112 aa)
	LOC101467814	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	rps27a	Ribosomal protein S27a. (192 aa)
	LOC101474574	Ubiquitin carboxyl-terminal hydrolase. (601 aa)
	LOC101477005	Cyclin A2; Belongs to the cyclin family. (434 aa)
	ppp2cb	Serine/threonine-protein phosphatase. (309 aa)
	mdm4	MDM4 regulator of p53. (504 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atm	ENSMZEP00005016530	ENSMZEP00005016548	ENSMZEP00005016530	Uncharacterized protein.	TAN domain-containing protein.	0.689
Atm	ENSMZEP00005024733	ENSMZEP00005016548	ENSMZEP00005024733	Uncharacterized protein.	Protein kinase domain-containing protein.	0.507
Atm	ENSMZEP00005024739	ENSMZEP00005016548	ENSMZEP00005024739	Uncharacterized protein.	Protein kinase domain-containing protein.	0.507
Atm	ENSMZEP00005031506	ENSMZEP00005016548	ENSMZEP00005031506	Uncharacterized protein.	Protein kinase domain-containing protein.	0.507
Atm	ENSMZEP00005037752	ENSMZEP00005016548	ENSMZEP00005037752	Uncharacterized protein.	Uncharacterized protein.	0.910
Atm	LOC101477005	ENSMZEP00005016548	ENSMZEP00005003277	Uncharacterized protein.	Cyclin A2; Belongs to the cyclin family.	0.641
Atm	LOC101480650	ENSMZEP00005016548	ENSMZEP00005029097	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.990
Atm	LOC101483949	ENSMZEP00005016548	ENSMZEP00005034735	Uncharacterized protein.	Death-domain associated protein.	0.439
Atm	ccna1	ENSMZEP00005016548	ENSMZEP00005032889	Uncharacterized protein.	Cyclin A1; Belongs to the cyclin family.	0.641
Atm	cdk1	ENSMZEP00005016548	ENSMZEP00005006265	Uncharacterized protein.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.507
Atm	cdk2	ENSMZEP00005016548	ENSMZEP00005030012	Uncharacterized protein.	Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.	0.507
Atm	chek2	ENSMZEP00005016548	ENSMZEP00005028018	Uncharacterized protein.	Checkpoint kinase 2.	0.951
Atm	mdm2	ENSMZEP00005016548	ENSMZEP00005028893	Uncharacterized protein.	MDM2 proto-oncogene.	0.876
Atm	mdm4	ENSMZEP00005016548	ENSMZEP00005000406	Uncharacterized protein.	MDM4 regulator of p53.	0.804
Atm	mtor	ENSMZEP00005016548	ENSMZEP00005006208	Uncharacterized protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.600
Atm	rps27a	ENSMZEP00005016548	ENSMZEP00005005788	Uncharacterized protein.	Ribosomal protein S27a.	0.618
ENSMZEP00005016530	Atm	ENSMZEP00005016530	ENSMZEP00005016548	TAN domain-containing protein.	Uncharacterized protein.	0.689
ENSMZEP00005016530	ENSMZEP00005024733	ENSMZEP00005016530	ENSMZEP00005024733	TAN domain-containing protein.	Protein kinase domain-containing protein.	0.509
ENSMZEP00005016530	ENSMZEP00005024739	ENSMZEP00005016530	ENSMZEP00005024739	TAN domain-containing protein.	Protein kinase domain-containing protein.	0.509
ENSMZEP00005016530	ENSMZEP00005031506	ENSMZEP00005016530	ENSMZEP00005031506	TAN domain-containing protein.	Protein kinase domain-containing protein.	0.509