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psmb4 psmb4 psmd7 psmd7 psme2 psme2 LOC101481073 LOC101481073 chek2 chek2 LOC101466398 LOC101466398 znf385b znf385b mdm2 mdm2 LOC101480650 LOC101480650 PSMA5 PSMA5 cdk2 cdk2 LOC101464547 LOC101464547 znf385c znf385c ENSMZEP00005031506 ENSMZEP00005031506 LOC101472230 LOC101472230 LOC101472537 LOC101472537 LOC101472814 LOC101472814 psmb8 psmb8 psmd8 psmd8 ccna1 ccna1 psma8 psma8 LOC101473263 LOC101473263 ENSMZEP00005034410 ENSMZEP00005034410 CCNE2 CCNE2 psmb2 psmb2 LOC101479706 LOC101479706 ENSMZEP00005036083 ENSMZEP00005036083 LOC101482250 LOC101482250 LOC101466438 LOC101466438 ENSMZEP00005037752 ENSMZEP00005037752 PSMC2 PSMC2 LOC101476664 LOC101476664 LOC101471805 LOC101471805 phf20 phf20 cdkn1b cdkn1b LOC101474553 LOC101474553 psmb1 psmb1 LOC101470828 LOC101470828 psmd10 psmd10 psme3 psme3 psma2 psma2 psmc1 psmc1 psme4 psme4 LOC101473243 LOC101473243 LOC101465041 LOC101465041 psmd14 psmd14 LOC101485013 LOC101485013 ENSMZEP00005018676 ENSMZEP00005018676 LOC101485859 LOC101485859 psma4 psma4 ENSMZEP00005016904 ENSMZEP00005016904 psma1 psma1 psmb3 psmb3 Atm Atm ENSMZEP00005016530 ENSMZEP00005016530 LOC101466273 LOC101466273 LOC101467117 LOC101467117 psme1 psme1 LOC101470307 LOC101470307 LOC101480458 LOC101480458 LOC101483887 LOC101483887 psma5 psma5 mdm4 mdm4 psmd9 psmd9 psmd12 psmd12 ccne1 ccne1 ENSMZEP00005002796 ENSMZEP00005002796 ENSMZEP00005002804 ENSMZEP00005002804 psmd5 psmd5 LOC101477005 LOC101477005 rps27a rps27a psmc3 psmc3 LOC101476359 LOC101476359 psmd6 psmd6 psmd3 psmd3 psmc6 psmc6 CDC25B CDC25B psmc5 psmc5 cop1 cop1 uba52 uba52 psmd13 psmd13 psmc4 psmc4 psma3 psma3 psmd1 psmd1 LOC101476208 LOC101476208 chek1 chek1 kxd1 kxd1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (256 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (330 aa)
psme2Proteasome activator subunit 2. (245 aa)
LOC101481073Proteasome subunit beta. (292 aa)
chek2Checkpoint kinase 2. (490 aa)
LOC101466398Uncharacterized protein. (558 aa)
znf385bZinc finger protein 385B. (586 aa)
mdm2MDM2 proto-oncogene. (523 aa)
LOC101480650Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (359 aa)
PSMA5Proteasome subunit alpha type. (221 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
LOC101464547Proteasome 26S subunit, non-ATPase 4b. (375 aa)
znf385cZinc finger protein 385C. (589 aa)
ENSMZEP00005031506Protein kinase domain-containing protein. (424 aa)
LOC101472230Proteasome subunit beta. (216 aa)
LOC101472537Proteasome subunit beta 12. (217 aa)
LOC101472814Proteasome subunit beta. (275 aa)
psmb8Proteasome subunit beta. (275 aa)
psmd8Proteasome 26S subunit, non-ATPase 8. (265 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (398 aa)
psma8Proteasome subunit alpha type. (251 aa)
LOC101473263Proteasome inhibitor subunit 1. (261 aa)
ENSMZEP00005034410Uncharacterized protein. (277 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (411 aa)
psmb2Proteasome subunit beta. (199 aa)
LOC101479706Proteasome 26S subunit, non-ATPase 4a. (372 aa)
ENSMZEP00005036083Uncharacterized protein. (149 aa)
LOC101482250Zinc finger protein 385A. (444 aa)
LOC101466438Proteasome subunit beta. (248 aa)
ENSMZEP00005037752Uncharacterized protein. (328 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (382 aa)
LOC101476664Proteasome subunit beta. (278 aa)
LOC101471805Proteasome subunit beta. (286 aa)
phf20PHD finger protein 20, a. (1003 aa)
cdkn1bCyclin-dependent kinase inhibitor 1Bb. (184 aa)
LOC101474553Cyclin-dependent kinase inhibitor 1A. (169 aa)
psmb1Proteasome subunit beta. (237 aa)
LOC101470828Proteasome 26S subunit, non-ATPase 11b. (422 aa)
psmd10Proteasome 26S subunit, non-ATPase 10. (243 aa)
psme3Proteasome activator subunit 3. (256 aa)
psma2Proteasome subunit alpha type. (234 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
psme4Proteasome activator subunit 4a. (1847 aa)
LOC101473243Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (381 aa)
LOC101465041Proteasome subunit alpha type. (246 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
LOC101485013Proteasome subunit alpha type. (248 aa)
ENSMZEP00005018676Uncharacterized protein. (143 aa)
LOC101485859Proteasome subunit beta. (281 aa)
psma4Proteasome subunit alpha type. (261 aa)
ENSMZEP00005016904Proteasome subunit beta. (278 aa)
psma1Proteasome subunit alpha type. (263 aa)
psmb3Proteasome subunit beta. (205 aa)
AtmUncharacterized protein. (139 aa)
ENSMZEP00005016530TAN domain-containing protein. (177 aa)
LOC101466273Uncharacterized protein. (178 aa)
LOC101467117Uncharacterized protein. (181 aa)
psme1Proteasome activator subunit 1. (255 aa)
LOC101470307Cyclin E2; Belongs to the cyclin family. (391 aa)
LOC101480458Uncharacterized protein. (427 aa)
LOC101483887Proteasome subunit alpha type. (246 aa)
psma5Proteasome subunit alpha type. (243 aa)
mdm4MDM4 regulator of p53. (504 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (204 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
ccne1Cyclin E1; Belongs to the cyclin family. (508 aa)
ENSMZEP00005002796BLM10_mid domain-containing protein. (567 aa)
ENSMZEP00005002804DUF3437 domain-containing protein. (320 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (504 aa)
LOC101477005Cyclin A2; Belongs to the cyclin family. (434 aa)
rps27aRibosomal protein S27a. (192 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (476 aa)
LOC101476359Cyclin-dependent kinase inhibitor 1Cb. (208 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (389 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (522 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
CDC25BCell division cycle 25B. (571 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (407 aa)
cop1COP1 E3 ubiquitin ligase. (715 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (379 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
psma3Proteasome subunit alpha type. (255 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (957 aa)
LOC101476208PCI domain-containing protein. (422 aa)
chek1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa)
kxd1KxDL motif containing 1. (192 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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