14 items (Maylandia zebra) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rab4b	RAB4B, member RAS oncogene family. (244 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1420 aa)
	LOC101485834	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (680 aa)
	ARF6	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (182 aa)
	grb2	Growth factor receptor-bound protein 2b. (217 aa)
	gab1	GRB2-associated binding protein 1. (777 aa)
	LOC101468680	Uncharacterized protein. (319 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	ENSMZEP00005027596	Uncharacterized protein. (112 aa)
	LOC101470907	CRK proto-oncogene, adaptor protein. (315 aa)
	LOC101485576	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (757 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
	LOC101473094	PH domain-containing protein. (781 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (305 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	LOC101468680	ENSMZEP00005015999	ENSMZEP00005014362	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Uncharacterized protein.	0.554
ARF6	LOC101470907	ENSMZEP00005015999	ENSMZEP00005005370	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	CRK proto-oncogene, adaptor protein.	0.554
ARF6	LOC101473094	ENSMZEP00005015999	ENSMZEP00005026141	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	PH domain-containing protein.	0.521
ARF6	LOC101485576	ENSMZEP00005015999	ENSMZEP00005032080	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	0.836
ARF6	LOC101485834	ENSMZEP00005015999	ENSMZEP00005017309	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	0.836
ARF6	crkl	ENSMZEP00005015999	ENSMZEP00005023898	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.554
ARF6	gab1	ENSMZEP00005015999	ENSMZEP00005012560	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	GRB2-associated binding protein 1.	0.521
ARF6	grb2	ENSMZEP00005015999	ENSMZEP00005005680	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Growth factor receptor-bound protein 2b.	0.643
ARF6	hgf	ENSMZEP00005015999	ENSMZEP00005026536	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.447
ARF6	met	ENSMZEP00005015999	ENSMZEP00005017860	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	MET proto-oncogene, receptor tyrosine kinase.	0.769
ARF6	rab4a	ENSMZEP00005015999	ENSMZEP00005014738	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	RAB4a, member RAS oncogene family.	0.494
ARF6	rab4b	ENSMZEP00005015999	ENSMZEP00005021846	ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	RAB4B, member RAS oncogene family.	0.494
ENSMZEP00005027596	LOC101468680	ENSMZEP00005027596	ENSMZEP00005014362	Uncharacterized protein.	Uncharacterized protein.	0.554
ENSMZEP00005027596	LOC101470907	ENSMZEP00005027596	ENSMZEP00005005370	Uncharacterized protein.	CRK proto-oncogene, adaptor protein.	0.554
ENSMZEP00005027596	LOC101473094	ENSMZEP00005027596	ENSMZEP00005026141	Uncharacterized protein.	PH domain-containing protein.	0.521
ENSMZEP00005027596	LOC101485576	ENSMZEP00005027596	ENSMZEP00005032080	Uncharacterized protein.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	0.836
ENSMZEP00005027596	LOC101485834	ENSMZEP00005027596	ENSMZEP00005017309	Uncharacterized protein.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	0.836
ENSMZEP00005027596	crkl	ENSMZEP00005027596	ENSMZEP00005023898	Uncharacterized protein.	V-crk avian sarcoma virus CT10 oncogene homolog-like.	0.554
ENSMZEP00005027596	gab1	ENSMZEP00005027596	ENSMZEP00005012560	Uncharacterized protein.	GRB2-associated binding protein 1.	0.521
ENSMZEP00005027596	grb2	ENSMZEP00005027596	ENSMZEP00005005680	Uncharacterized protein.	Growth factor receptor-bound protein 2b.	0.643