69 items (Maylandia zebra) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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Your Input:
	LOC101478937	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (296 aa)
	LOC101478712	dCMP deaminase. (439 aa)
	LOC101485396	5'-nucleotidase, cytosolic IAa. (387 aa)
	LOC101481260	Ectonucleotide pyrophosphatase/phosphodiesterase 1. (795 aa)
	tyms	Thymidylate synthetase. (325 aa)
	umps	Uridine monophosphate synthetase. (485 aa)
	dhodh	Dihydroorotate dehydrogenase (quinone), mitochondrial; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (412 aa)
	LOC101468566	5'-nucleotidase, cytosolic IB b. (361 aa)
	entpd1	Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (498 aa)
	upb1	Ureidopropionase, beta. (383 aa)
	uck1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (275 aa)
	rrm2b	Ribonucleotide reductase M2 b. (349 aa)
	LOC101470113	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (588 aa)
	entpd6	Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (440 aa)
	LOC101471779	NDK domain-containing protein; Belongs to the NDK family. (149 aa)
	dck	Deoxycytidine kinase. (356 aa)
	CMPK1	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (219 aa)
	NT5E	5'-nucleotidase, ecto (CD73); Belongs to the 5'-nucleotidase family. (585 aa)
	cmpk2	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. (421 aa)
	LOC101466690	Uridine-cytidine kinase; Belongs to the uridine kinase family. (545 aa)
	LOC101473382	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (497 aa)
	NT5M	5',3'-nucleotidase, mitochondrial. (229 aa)
	LOC101487835	Nucleoside diphosphate kinase. (152 aa)
	LOC101471709	Zgc:136858. (702 aa)
	dut	Deoxyuridine triphosphatase. (181 aa)
	tk1	Thymidine kinase. (233 aa)
	LOC101480607	Calcium activated nucleotidase 1b. (417 aa)
	nme7	Nucleoside diphosphate kinase 7; Belongs to the NDK family. (379 aa)
	dctpp1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (161 aa)
	upp2	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (313 aa)
	nt5c2	5'-nucleotidase, cytosolic IIb. (562 aa)
	dtymk	Deoxythymidylate kinase (thymidylate kinase). (204 aa)
	nt5c3a	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (331 aa)
	LOC101481213	Uridine-cytidine kinase; Belongs to the uridine kinase family. (262 aa)
	LOC101482858	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (300 aa)
	LOC101483765	Nucleoside diphosphate kinase. (201 aa)
	dpyd	Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (1021 aa)
	LOC101473239	Uridine-cytidine kinase; Belongs to the uridine kinase family. (262 aa)
	LOC101481315	Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family. (430 aa)
	uprt	Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae). (256 aa)
	dpys	Dihydropyrimidinase. (496 aa)
	LOC101479761	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (592 aa)
	LOC112430046	Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (598 aa)
	cant1	Calcium activated nucleotidase 1a. (417 aa)
	NT5E-2	5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (575 aa)
	RRM2	Ribonucleotide reductase regulatory subunit M2. (385 aa)
	RRM2-2	Ribonucleotide reductase regulatory subunit M2. (385 aa)
	LOC101471226	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
	nme6	Nucleoside diphosphate kinase. (182 aa)
	LOC101481005	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
	LOC101476861	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
	Ak9	Uncharacterized protein. (172 aa)
	LOC101487870	5'-nucleotidase, cytosolic II, like 1. (496 aa)
	tk2	Thymidine kinase 2. (271 aa)
	TYMP	Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (452 aa)
	entpd5	Ectonucleoside triphosphate diphosphohydrolase 5a; Belongs to the GDA1/CD39 NTPase family. (504 aa)
	LOC101477825	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (295 aa)
	NT5C3B	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (317 aa)
	NT5C3B-2	5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (333 aa)
	uckl1	Uridine-cytidine kinase; Belongs to the uridine kinase family. (551 aa)
	LOC101486224	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (291 aa)
	LOC101465766	Zgc:110540. (270 aa)
	LOC101476695	Uridine-cytidine kinase; Belongs to the uridine kinase family. (517 aa)
	nudt2	Nudix (nucleoside diphosphate linked moiety X)-type motif 2. (198 aa)
	cda	Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (165 aa)
	LOC101482474	5'-nucleotidase, cytosolic IAb. (371 aa)
	ENSMZEP00005037469	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (228 aa)
	LOC112429805	Uncharacterized protein. (129 aa)
	LOC112432279	CPSase_sm_chain domain-containing protein. (261 aa)

Your Current Organism:

Maylandia zebra

NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ak9	CMPK1	ENSMZEP00005023202	ENSMZEP00005007156	Uncharacterized protein.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.935
Ak9	ENSMZEP00005037469	ENSMZEP00005023202	ENSMZEP00005037469	Uncharacterized protein.	Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family.	0.482
Ak9	LOC101465766	ENSMZEP00005023202	ENSMZEP00005033411	Uncharacterized protein.	Zgc:110540.	0.922
Ak9	LOC101468566	ENSMZEP00005023202	ENSMZEP00005002689	Uncharacterized protein.	5'-nucleotidase, cytosolic IB b.	0.713
Ak9	LOC101470113	ENSMZEP00005023202	ENSMZEP00005005207	Uncharacterized protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.945
Ak9	LOC101471779	ENSMZEP00005023202	ENSMZEP00005005440	Uncharacterized protein.	NDK domain-containing protein; Belongs to the NDK family.	0.952
Ak9	LOC101473382	ENSMZEP00005023202	ENSMZEP00005008344	Uncharacterized protein.	Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family.	0.912
Ak9	LOC101476861	ENSMZEP00005023202	ENSMZEP00005022374	Uncharacterized protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.955
Ak9	LOC101479761	ENSMZEP00005023202	ENSMZEP00005016504	Uncharacterized protein.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.945
Ak9	LOC101480607	ENSMZEP00005023202	ENSMZEP00005010844	Uncharacterized protein.	Calcium activated nucleotidase 1b.	0.741
Ak9	LOC101481005	ENSMZEP00005023202	ENSMZEP00005021391	Uncharacterized protein.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.955
Ak9	LOC101481260	ENSMZEP00005023202	ENSMZEP00005001449	Uncharacterized protein.	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	0.903
Ak9	LOC101481315	ENSMZEP00005023202	ENSMZEP00005014783	Uncharacterized protein.	Ectonucleoside triphosphate diphosphohydrolase 5b; Belongs to the GDA1/CD39 NTPase family.	0.726
Ak9	LOC101482474	ENSMZEP00005023202	ENSMZEP00005036274	Uncharacterized protein.	5'-nucleotidase, cytosolic IAb.	0.713
Ak9	LOC101483765	ENSMZEP00005023202	ENSMZEP00005014162	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.952
Ak9	LOC101485396	ENSMZEP00005023202	ENSMZEP00005001136	Uncharacterized protein.	5'-nucleotidase, cytosolic IAa.	0.713
Ak9	LOC101487835	ENSMZEP00005023202	ENSMZEP00005008995	Uncharacterized protein.	Nucleoside diphosphate kinase.	0.952
Ak9	LOC101487870	ENSMZEP00005023202	ENSMZEP00005024163	Uncharacterized protein.	5'-nucleotidase, cytosolic II, like 1.	0.650
Ak9	LOC112429805	ENSMZEP00005023202	ENSMZEP00005037858	Uncharacterized protein.	Uncharacterized protein.	0.650
Ak9	LOC112430046	ENSMZEP00005023202	ENSMZEP00005017175	Uncharacterized protein.	Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family.	0.693