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APK84_gp11 APK84_gp11 APK84_gp10 APK84_gp10 APK84_gp07 APK84_gp07 APK84_gp01 APK84_gp01 LOC101486557 LOC101486557 LOC101470436 LOC101470436 LOC101486104 LOC101486104 cacnb2 cacnb2 CACNG2 CACNG2 cacng5 cacng5 cacng4 cacng4 cacng1 cacng1 LOC101479636 LOC101479636 LOC101471450 LOC101471450 LOC101471937 LOC101471937 ENSMZEP00005003053 ENSMZEP00005003053 ACTC1 ACTC1 LOC101474381 LOC101474381 LOC101476777 LOC101476777 LOC101482742 LOC101482742 MYL2 MYL2 LOC101482597 LOC101482597 LOC101483574 LOC101483574 LOC101486527 LOC101486527 slc9a7 slc9a7 LOC101483500 LOC101483500 LOC101466516 LOC101466516 LOC101473310 LOC101473310 LOC101484391 LOC101484391 LOC101470161 LOC101470161 LOC101467933 LOC101467933 LOC101483772 LOC101483772 ENSMZEP00005008375 ENSMZEP00005008375 LOC101471831 LOC101471831 LOC101480003 LOC101480003 LOC101470489 LOC101470489 LOC101474979 LOC101474979 atp1b4 atp1b4 cacng3 cacng3 LOC101483030 LOC101483030 slc9a1 slc9a1 LOC101484790 LOC101484790 LOC101484155 LOC101484155 LOC101470454 LOC101470454 tpm4 tpm4 LOC101476439 LOC101476439 LOC101478334 LOC101478334 slc8a3 slc8a3 LOC101465335 LOC101465335 ACTA1 ACTA1 LOC101480992 LOC101480992 LOC101478425 LOC101478425 LOC101478451 LOC101478451 ENSMZEP00005015405 ENSMZEP00005015405 ENSMZEP00005015737 ENSMZEP00005015737 LOC101463895 LOC101463895 LOC101467139 LOC101467139 LOC101485620 LOC101485620 LOC101473643 LOC101473643 LOC101468370 LOC101468370 LOC101482453 LOC101482453 LOC101482156 LOC101482156 LOC101467805 LOC101467805 LOC101483122 LOC101483122 LOC101487495 LOC101487495 LOC101476618 LOC101476618 LOC101474550 LOC101474550 LOC105941235 LOC105941235 MYH6 MYH6 LOC101483728 LOC101483728 cacna2d2 cacna2d2 LOC101484004 LOC101484004 LOC101480083 LOC101480083 LOC101485486 LOC101485486 LOC101481740 LOC101481740 LOC101482025 LOC101482025 cacng6 cacng6 LOC101465457 LOC101465457 UQCRFS1 UQCRFS1 LOC112436572 LOC112436572 LOC101475874 LOC101475874 LOC101466725 LOC101466725 LOC101477070 LOC101477070 LOC101477348 LOC101477348 LOC101477629 LOC101477629 LOC101476791 LOC101476791 LOC101476311 LOC101476311 atp2a2 atp2a2 LOC101479997 LOC101479997 LOC101473612 LOC101473612 LOC101487398 LOC101487398 cacnb4 cacnb4 LOC101473367 LOC101473367 Myl4 Myl4 LOC101481732 LOC101481732 LOC101480497 LOC101480497 LOC112431926 LOC112431926 LOC101475299 LOC101475299 TPM1 TPM1 cacnb1 cacnb1 LOC101467496 LOC101467496 COX5B COX5B LOC101475255 LOC101475255 atp2a3 atp2a3 LOC101475078 LOC101475078 LOC101481172 LOC101481172 LOC101474423 LOC101474423 LOC101467086 LOC101467086 UQCR11 UQCR11 LOC112433101 LOC112433101 TNNC1 TNNC1 LOC101487824 LOC101487824 cacnb3 cacnb3 LOC101464569 LOC101464569 MYL2-2 MYL2-2 CACNA2D3 CACNA2D3 LOC101480990 LOC101480990 cacna1s cacna1s slc8a1 slc8a1 ENSMZEP00005036792 ENSMZEP00005036792 COX5A COX5A
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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gene co-occurrence
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APK84_gp11Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (529 aa)
APK84_gp10Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (230 aa)
APK84_gp07Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (261 aa)
APK84_gp01Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
LOC101486557Cytochrome c oxidase subunit 7A1. (81 aa)
LOC101470436Cytochrome c oxidase subunit 6A, mitochondrial. (145 aa)
LOC101486104Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (411 aa)
cacnb2Calcium channel, voltage-dependent, beta 2a. (712 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (328 aa)
cacng5Calcium channel, voltage-dependent, gamma subunit 5a. (277 aa)
cacng4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (334 aa)
cacng1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (230 aa)
LOC101479636Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (415 aa)
LOC101471450Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
LOC101471937Calcium channel, voltage-dependent, gamma subunit 6a. (287 aa)
ENSMZEP00005003053Calcium channel, voltage-dependent, gamma subunit 8a. (294 aa)
ACTC1Zgc:86709. (377 aa)
LOC101474381Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (287 aa)
LOC101476777Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1035 aa)
LOC101482742Cytochrome c oxidase subunit 7A2 like. (115 aa)
MYL2Myosin, light chain 2b, regulatory, cardiac, slow. (168 aa)
LOC101482597Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (301 aa)
LOC101483574Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (930 aa)
LOC101486527Calcium channel, voltage-dependent, gamma subunit 5b. (276 aa)
slc9a7Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (711 aa)
LOC101483500Ubiquinol-cytochrome c reductase core protein 2a. (459 aa)
LOC101466516Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
LOC101473310Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (99 aa)
LOC101484391Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (278 aa)
LOC101470161Actin alpha 1, skeletal muscle. (377 aa)
LOC101467933Cytochrome c oxidase subunit 5Ab. (150 aa)
LOC101483772Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (322 aa)
ENSMZEP00005008375Asp-B-Hydro_N domain-containing protein. (145 aa)
LOC101471831Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (690 aa)
LOC101480003Uncharacterized protein. (60 aa)
LOC101470489Troponin C type 1b (slow). (161 aa)
LOC101474979Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (87 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (343 aa)
cacng3Calcium voltage-gated channel auxiliary subunit gamma 3. (315 aa)
LOC101483030Cytochrome c oxidase subunit 6C. (76 aa)
slc9a1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (787 aa)
LOC101484790Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (293 aa)
LOC101484155Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
LOC101470454Uncharacterized protein; Belongs to the tropomyosin family. (355 aa)
tpm4Tropomyosin 4a; Belongs to the tropomyosin family. (284 aa)
LOC101476439Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (297 aa)
LOC101478334Uncharacterized protein. (76 aa)
slc8a3Solute carrier family 8 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (925 aa)
LOC101465335Ubiquinol-cytochrome c reductase core protein 1. (478 aa)
ACTA1Actin alpha 1, skeletal muscle. (377 aa)
LOC101480992Cytochrome c oxidase subunit 5B2. (126 aa)
LOC101478425Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
LOC101478451Calcium channel, voltage-dependent, gamma subunit 3a. (333 aa)
ENSMZEP00005015405Asp-B-Hydro_N domain-containing protein. (216 aa)
ENSMZEP00005015737Uncharacterized protein. (224 aa)
LOC101463895Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa)
LOC101467139Ubiquinol-cytochrome c reductase, complex III subunit VII. (100 aa)
LOC101485620Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2069 aa)
LOC101473643Cytochrome c oxidase subunit 4I1. (169 aa)
LOC101468370Uncharacterized protein. (382 aa)
LOC101482453Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (228 aa)
LOC101482156Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (324 aa)
LOC101467805Solute carrier family 8 member 4a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (962 aa)
LOC101483122Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1065 aa)
LOC101487495Solute carrier family 8 member 1a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (965 aa)
LOC101476618Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (996 aa)
LOC101474550Cytochrome c oxidase subunit 7C. (63 aa)
LOC105941235Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
MYH6Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
LOC101483728Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1943 aa)
cacna2d2Calcium channel, voltage-dependent, alpha 2/delta subunit 2a. (1122 aa)
LOC101484004Myosin heavy chain 7-like; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1930 aa)
LOC101480083Cytochrome c-1. (307 aa)
LOC101485486Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (294 aa)
LOC101481740Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (313 aa)
LOC101482025Calcium channel, voltage-dependent, gamma subunit 8b. (416 aa)
cacng6Calcium channel, voltage-dependent, gamma subunit 6b. (263 aa)
LOC101465457Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (86 aa)
UQCRFS1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (240 aa)
LOC112436572Uncharacterized protein. (70 aa)
LOC101475874Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
LOC101466725Calcium channel, voltage-dependent, beta 4b subunit. (503 aa)
LOC101477070Sodium/potassium-transporting ATPase subunit alpha. (1022 aa)
LOC101477348Sodium/potassium-transporting ATPase subunit alpha. (974 aa)
LOC101477629Sodium/potassium-transporting ATPase subunit alpha. (945 aa)
LOC101476791Sodium/potassium-transporting ATPase subunit alpha. (963 aa)
LOC101476311Sodium/potassium-transporting ATPase subunit alpha. (1024 aa)
atp2a2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1043 aa)
LOC101479997Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1. (301 aa)
LOC101473612Sodium/potassium-transporting ATPase subunit alpha. (1010 aa)
LOC101487398Ubiquinol-cytochrome c reductase, complex III subunit X. (62 aa)
cacnb4Calcium channel, voltage-dependent, beta 4a subunit. (518 aa)
LOC101473367Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (302 aa)
Myl4Uncharacterized protein. (120 aa)
LOC101481732Uncharacterized protein; Belongs to the tropomyosin family. (249 aa)
LOC101480497Asp-B-Hydro_N domain-containing protein. (956 aa)
LOC112431926Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (288 aa)
LOC101475299Cytochrome c oxidase subunit 4I2. (174 aa)
TPM1Uncharacterized protein; Belongs to the tropomyosin family. (284 aa)
cacnb1Calcium channel, voltage-dependent, beta 1 subunit. (669 aa)
LOC101467496Uncharacterized protein. (126 aa)
COX5BCytochrome c oxidase subunit 5B. (126 aa)
LOC101475255Cytochrome c oxidase subunit 6A, mitochondrial. (103 aa)
atp2a3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1004 aa)
LOC101475078Solute carrier family 8 member 2a; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (919 aa)
LOC101481172Sodium/potassium-transporting ATPase subunit alpha. (1010 aa)
LOC101474423Tropomyosin 4; Belongs to the tropomyosin family. (284 aa)
LOC101467086Solute carrier family 8 member 2b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (948 aa)
UQCR11Ubiquinol-cytochrome c reductase, complex III subunit XI. (56 aa)
LOC112433101Asp-B-Hydro_N domain-containing protein. (287 aa)
TNNC1Troponin C type 1a (slow). (161 aa)
LOC101487824Sodium/potassium-transporting ATPase subunit alpha. (1022 aa)
cacnb3Calcium channel, voltage-dependent, beta 3a. (567 aa)
LOC101464569Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (735 aa)
MYL2-2Myosin light chain 2. (169 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1051 aa)
LOC101480990Troponin T type 2a (cardiac). (282 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1847 aa)
slc8a1Solute carrier family 8 member 1b; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (947 aa)
ENSMZEP00005036792B30.2/SPRY domain-containing protein. (336 aa)
COX5ACytochrome c oxidase subunit 5A. (149 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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