STRINGSTRING
bmpr2 bmpr2 nog nog LOC101467323 LOC101467323 nodal nodal BMP7 BMP7 LOC101464606 LOC101464606 LOC101470081 LOC101470081 LOC101470571 LOC101470571 pitx2 pitx2 SMURF2 SMURF2 ppp2cb ppp2cb LOC101470473 LOC101470473 bmp4 bmp4 LOC101475792 LOC101475792 rbx1 rbx1 LOC101472412 LOC101472412 ep300 ep300 LOC101479229 LOC101479229 chrd chrd LOC101467023 LOC101467023 grem1 grem1 ENSMZEP00005005333 ENSMZEP00005005333 LOC101474249 LOC101474249 crebbp crebbp bmpr1a bmpr1a LOC101469682 LOC101469682 LOC101485614 LOC101485614 bmp5 bmp5 LOC101466107 LOC101466107 LOC101466608 LOC101466608 LOC101464356 LOC101464356 THSD4 THSD4 id2 id2 LOC101470930 LOC101470930 amh amh LOC101464704 LOC101464704 sp1 sp1 LOC101486019 LOC101486019 INHBC INHBC smurf1 smurf1 rbl1 rbl1 LOC101468970 LOC101468970 LOC101476960 LOC101476960 ACVR1C ACVR1C acvr1 acvr1 LOC101483436 LOC101483436 skp1 skp1 ppp2ca ppp2ca LOC101474234 LOC101474234 gdf5 gdf5 smad1 smad1 LOC101487021 LOC101487021 id1 id1 GREM1 GREM1 LOC101476065 LOC101476065 bmp2 bmp2 NBL1 NBL1 LOC106676202 LOC106676202 LOC106676198 LOC106676198 LOC112435583 LOC112435583 LOC101484183 LOC101484183 ENSMZEP00005015695 ENSMZEP00005015695 LOC101477046 LOC101477046 LOC101487597 LOC101487597 LOC101485102 LOC101485102 LOC101484891 LOC101484891 SMAD3 SMAD3 fst fst LOC101480329 LOC101480329 LOC101478146 LOC101478146 cul1 cul1 neo1 neo1 LOC101486443 LOC101486443 ACVR2A ACVR2A LOC101479046 LOC101479046 ppp2r1b ppp2r1b e2f4 e2f4 TGFB3 TGFB3 bambi bambi LOC101466778 LOC101466778 LOC112430746 LOC112430746 ENSMZEP00005022544 ENSMZEP00005022544 rgmb rgmb LOC101479411 LOC101479411 bmp6 bmp6 LOC101469924 LOC101469924 LOC101479208 LOC101479208 LOC101485383 LOC101485383 LOC101472170 LOC101472170 myc myc LOC101481773 LOC101481773 LOC101481185 LOC101481185 ltbp1 ltbp1 inhba inhba LOC101471656 LOC101471656 smad7 smad7 LOC101478569 LOC101478569 LOC101478446 LOC101478446 LOC101479519 LOC101479519 mapk1 mapk1 LOC101470853 LOC101470853 LOC101465971 LOC101465971 rgma rgma LOC101465438 LOC101465438 tfdp1 tfdp1 smad6 smad6 LOC101465875 LOC101465875 fmod fmod LOC101479954 LOC101479954 LOC101473892 LOC101473892 zfyve9 zfyve9 LOC101465379 LOC101465379 LOC101467600 LOC101467600 LOC101486034 LOC101486034 smad9 smad9 rock1 rock1 tgfb2 tgfb2 LOC101465777 LOC101465777 ENSMZEP00005033929 ENSMZEP00005033929 LOC101483990 LOC101483990 LOC101473671 LOC101473671 bmp8a bmp8a gdf6 gdf6 TGFBR2 TGFBR2 LOC101472998 LOC101472998 LOC101464339 LOC101464339 ACVR1B ACVR1B LOC101486234 LOC101486234 grem2 grem2 LOC101473497 LOC101473497 LOC101468013 LOC101468013
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1067 aa)
nogNoggin; Belongs to the noggin family. (222 aa)
LOC101467323Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
nodalNodal-related 2. (386 aa)
BMP7Bone morphogenetic protein 7. (425 aa)
LOC101464606Transcriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (367 aa)
LOC101470081Zgc:113307. (383 aa)
LOC101470571Fibromodulin a. (348 aa)
pitx2Homeobox protein. (313 aa)
SMURF2E3 ubiquitin-protein ligase. (776 aa)
ppp2cbSerine/threonine-protein phosphatase. (309 aa)
LOC101470473Mothers against decapentaplegic homolog. (489 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
LOC101475792Lefty1. (357 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
LOC101472412Ras homolog family member Cb. (193 aa)
ep300E1A binding protein p300 b. (2765 aa)
LOC101479229Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
chrdChordin; Belongs to the chordin family. (951 aa)
LOC101467023CREB binding protein a. (2368 aa)
grem1Gremlin 1a, DAN family BMP antagonist. (179 aa)
ENSMZEP00005005333TNF_2 domain-containing protein. (188 aa)
LOC101474249Inhibitor of DNA binding 3. (117 aa)
crebbpCREB binding protein b. (2473 aa)
bmpr1aReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (529 aa)
LOC101469682E3 ubiquitin-protein ligase. (844 aa)
LOC101485614Mothers against decapentaplegic homolog. (510 aa)
bmp5Bone morphogenetic protein 5. (456 aa)
LOC101466107Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101466608Decorin; May affect the rate of fibrils formation. (358 aa)
LOC101464356Mothers against decapentaplegic homolog. (473 aa)
THSD4Thrombospondin type 1 domain containing 4. (971 aa)
id2Inhibitor of DNA binding 2a. (136 aa)
LOC101470930TGF_BETA_2 domain-containing protein. (379 aa)
amhAnti-Mullerian hormone. (513 aa)
LOC101464704Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
sp1Sp1 transcription factor. (707 aa)
LOC101486019RGM domain family, member D. (463 aa)
INHBCInhibin subunit beta C. (374 aa)
smurf1E3 ubiquitin-protein ligase. (730 aa)
rbl1Retinoblastoma-like 1 (p107). (1062 aa)
LOC101468970Uncharacterized protein. (90 aa)
LOC101476960Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (685 aa)
LOC101483436Zinc finger, FYVE domain containing 16. (1439 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
LOC101474234Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (394 aa)
gdf5Growth differentiation factor 5. (477 aa)
smad1Mothers against decapentaplegic homolog. (467 aa)
LOC101487021Thrombospondin 1a. (1170 aa)
id1Inhibitor of DNA binding 1, HLH protein. (131 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (137 aa)
LOC101476065Uncharacterized protein. (283 aa)
bmp2Bone morphogenetic protein 2b. (418 aa)
NBL1NBL1, DAN family BMP antagonist. (187 aa)
LOC106676202Uncharacterized protein. (86 aa)
LOC106676198Uncharacterized protein. (87 aa)
LOC112435583Uncharacterized protein. (86 aa)
LOC101484183Growth differentiation factor 6a. (440 aa)
ENSMZEP00005015695Noggin; Belongs to the noggin family. (208 aa)
LOC101477046TGF_BETA_2 domain-containing protein. (391 aa)
LOC101487597Serine/threonine-protein phosphatase. (309 aa)
LOC101485102Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (500 aa)
LOC101484891Mothers against decapentaplegic homolog. (501 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
fstFollistatin a. (348 aa)
LOC101480329Inhibin subunit beta B. (404 aa)
LOC101478146Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (470 aa)
cul1Cullin 1b; Belongs to the cullin family. (776 aa)
neo1Neogenin 1b. (1426 aa)
LOC101486443Uncharacterized protein. (87 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
LOC101479046Myelocytomatosis oncogene homolog. (355 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (595 aa)
e2f4E2F transcription factor 4. (382 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC101466778Bone morphogenetic protein 16. (510 aa)
LOC112430746Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (486 aa)
ENSMZEP00005022544TGF_BETA_2 domain-containing protein. (111 aa)
rgmbRepulsive guidance molecule BMP co-receptor b. (474 aa)
LOC101479411Hemojuvelin BMP co-receptor. (418 aa)
bmp6Bone morphogenetic protein 6. (428 aa)
LOC101469924Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC101479208Southpaw. (412 aa)
LOC101485383Mothers against decapentaplegic homolog. (606 aa)
LOC101472170TNF_2 domain-containing protein. (237 aa)
mycTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (437 aa)
LOC101481773Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
LOC101481185Mothers against decapentaplegic homolog. (503 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1446 aa)
inhbaTGF_BETA_2 domain-containing protein. (391 aa)
LOC101471656Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4). (131 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
LOC101478569Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (519 aa)
LOC101478446Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (613 aa)
LOC101479519Inhibin subunit beta Aa. (450 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC101470853Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
LOC101465971Uncharacterized protein. (193 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (446 aa)
LOC101465438TGFB-induced factor homeobox 1. (307 aa)
tfdp1Transcription factor. (413 aa)
smad6Mothers against decapentaplegic homolog. (488 aa)
LOC101465875Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (509 aa)
fmodFibromodulin b. (347 aa)
LOC101479954E2F_TDP domain-containing protein. (307 aa)
LOC101473892Transforming growth factor beta; Belongs to the TGF-beta family. (383 aa)
zfyve9Zinc finger, FYVE domain containing 9a. (1204 aa)
LOC101465379Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (514 aa)
LOC101467600Anti-dorsalizing morphogenic protein. (380 aa)
LOC101486034E2F transcription factor 5. (360 aa)
smad9Mothers against decapentaplegic homolog. (468 aa)
rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1370 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC101465777Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (596 aa)
ENSMZEP00005033929Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (627 aa)
LOC101483990Inhibitor of DNA binding 4. (141 aa)
LOC101473671Bone morphogenetic protein 7b. (427 aa)
bmp8aBone morphogenetic protein 8a. (452 aa)
gdf6Growth differentiation factor 6b. (436 aa)
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (538 aa)
LOC101472998Homeobox domain-containing protein. (564 aa)
LOC101464339Uncharacterized protein. (217 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (499 aa)
LOC101486234Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (192 aa)
LOC101473497Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LOC101468013E1A binding protein p300 a. (2775 aa)
Your Current Organism:
Maylandia zebra
NCBI taxonomy Id: 106582
Other names: M. zebra, Metriaclima zebra, Pseudotropheus zebra, zebra mbuna
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