(35 nodes) Mixed, incl. Degradation of aromatic compounds, and Coenzyme A transferase network (Amycolatopsis methanolica)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

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Your Input:
	pcaC	Carboxymuconolactone decarboxylase. (167 aa)
	catD2	Alpha/beta hydrolase fold protein. (151 aa)
	AIJ21906.1	Alpha/beta hydrolase fold protein. (262 aa)
	catC	Muconolactone isomerase; Belongs to the muconolactone Delta-isomerase family. (92 aa)
	catA	Catechol 1,2-dioxygenase. (281 aa)
	AIJ22268.1	Mandelate racemase/muconate lactonizing enzyme-like protein. (367 aa)
	AIJ22269.1	LysR-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (300 aa)
	benA-3	Benzoate dioxygenase alpha subunit. (449 aa)
	benB	Benzoate dioxygenase beta subunit. (168 aa)
	AIJ22272.1	Oxidoreductase FAD-binding region. (880 aa)
	benK	MFS family benzoate membrane transporter. (436 aa)
	AIJ22274.1	LuxR family transcriptional regulator. (862 aa)
	benE	Benzoate membrane transport protein BenE. (411 aa)
	AIJ22276.1	CsbD family protein; Belongs to the UPF0337 (CsbD) family. (61 aa)
	AIJ22436.1	Monooxygenase. (232 aa)
	mhpC-2	Alpha/beta hydrolase fold protein. (271 aa)
	catC-2	Muconolactone delta-isomerase. (91 aa)
	AIJ23671.1	Vanillate O-demethylase oxidoreductase. (233 aa)
	AIJ23672.1	Anthranilate 1,2-dioxygenase, large subunit. (139 aa)
	AIJ23673.1	IacB protein. (126 aa)
	AIJ23674.1	Aromatic ring hydroxylase. (199 aa)
	catI	3-oxoadipate CoA-transferase. (309 aa)
	gctB	3-oxoadipate:succinyl-CoA transferase, B subunit. (254 aa)
	pcaR-5	Transcriptional regulator, IclR family. (264 aa)
	pcaC-2	4-carboxymuconolactone decarboxylase. (133 aa)
	pcaD	3-oxoadipate enol-lactonase. (253 aa)
	pcaB	3-carboxy-cis,cis-muconate cycloisomerase. (441 aa)
	pcaG	Protocatechuate 3,4-dioxygenase, alpha subunit. (181 aa)
	pcaH	Protocatechuate 3,4-dioxygenase, beta subunit. (247 aa)
	fadA-9	acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
	gctB-2	3-oxoadipate CoA-transferase. (254 aa)
	gctA	3-oxoadipate CoA-transferase. (272 aa)
	AIJ25491.1	Hypothetical protein. (55 aa)
	AIJ25493.1	Haloacid dehalogenase domain-containing protein hydrolase. (230 aa)
	menC-3	Muconate and chloromuconate cycloisomerase; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (199 aa)

Your Current Organism:

Amycolatopsis methanolica

NCBI taxonomy Id: 1068978
Other names: A. methanolica 239, Amycolatopsis methanolica 239, Amycolatopsis methanolica IFO 15065, Amycolatopsis methanolica IMSNU 20055, Amycolatopsis methanolica KCTC 9411, Amycolatopsis methanolica NCIB 11946, Amycolatopsis methanolica NRRL B-24139, Amycolatopsis methanolica str. 239, Amycolatopsis methanolica strain 239

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIJ21906.1	catC	AMETH_1814	AMETH_2174	Alpha/beta hydrolase fold protein.	Muconolactone isomerase; Belongs to the muconolactone Delta-isomerase family.	0.907
AIJ21906.1	catC-2	AMETH_1814	AMETH_2832	Alpha/beta hydrolase fold protein.	Muconolactone delta-isomerase.	0.907
AIJ21906.1	catD2	AMETH_1814	AMETH_1613	Alpha/beta hydrolase fold protein.	Alpha/beta hydrolase fold protein.	0.949
AIJ21906.1	mhpC-2	AMETH_1814	AMETH_2411	Alpha/beta hydrolase fold protein.	Alpha/beta hydrolase fold protein.	0.716
AIJ21906.1	pcaC	AMETH_1814	AMETH_1373	Alpha/beta hydrolase fold protein.	Carboxymuconolactone decarboxylase.	0.916
AIJ21906.1	pcaC-2	AMETH_1814	AMETH_5391	Alpha/beta hydrolase fold protein.	4-carboxymuconolactone decarboxylase.	0.987
AIJ21906.1	pcaD	AMETH_1814	AMETH_5392	Alpha/beta hydrolase fold protein.	3-oxoadipate enol-lactonase.	0.920
AIJ22268.1	AIJ22269.1	AMETH_2176	AMETH_2177	Mandelate racemase/muconate lactonizing enzyme-like protein.	LysR-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.	0.860
AIJ22268.1	AIJ22272.1	AMETH_2176	AMETH_2180	Mandelate racemase/muconate lactonizing enzyme-like protein.	Oxidoreductase FAD-binding region.	0.875
AIJ22268.1	AIJ22274.1	AMETH_2176	AMETH_2182	Mandelate racemase/muconate lactonizing enzyme-like protein.	LuxR family transcriptional regulator.	0.816
AIJ22268.1	benA-3	AMETH_2176	AMETH_2178	Mandelate racemase/muconate lactonizing enzyme-like protein.	Benzoate dioxygenase alpha subunit.	0.842
AIJ22268.1	benB	AMETH_2176	AMETH_2179	Mandelate racemase/muconate lactonizing enzyme-like protein.	Benzoate dioxygenase beta subunit.	0.862
AIJ22268.1	benK	AMETH_2176	AMETH_2181	Mandelate racemase/muconate lactonizing enzyme-like protein.	MFS family benzoate membrane transporter.	0.633
AIJ22268.1	catA	AMETH_2176	AMETH_2175	Mandelate racemase/muconate lactonizing enzyme-like protein.	Catechol 1,2-dioxygenase.	0.965
AIJ22268.1	catC	AMETH_2176	AMETH_2174	Mandelate racemase/muconate lactonizing enzyme-like protein.	Muconolactone isomerase; Belongs to the muconolactone Delta-isomerase family.	0.964
AIJ22268.1	catC-2	AMETH_2176	AMETH_2832	Mandelate racemase/muconate lactonizing enzyme-like protein.	Muconolactone delta-isomerase.	0.870
AIJ22268.1	pcaG	AMETH_2176	AMETH_5394	Mandelate racemase/muconate lactonizing enzyme-like protein.	Protocatechuate 3,4-dioxygenase, alpha subunit.	0.406
AIJ22269.1	AIJ22268.1	AMETH_2177	AMETH_2176	LysR-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.	Mandelate racemase/muconate lactonizing enzyme-like protein.	0.860
AIJ22269.1	AIJ22272.1	AMETH_2177	AMETH_2180	LysR-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.	Oxidoreductase FAD-binding region.	0.683
AIJ22269.1	AIJ22274.1	AMETH_2177	AMETH_2182	LysR-type transcriptional regulator; Belongs to the LysR transcriptional regulatory family.	LuxR family transcriptional regulator.	0.628

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