STRINGSTRING
ruvA ruvA ruvB ruvB AIJ23643.1 AIJ23643.1 AIJ24182.1 AIJ24182.1 AIJ24871.1 AIJ24871.1 AIJ21118.1 AIJ21118.1 ku-2 ku-2 AIJ21083.1 AIJ21083.1 uvrD uvrD ku ku AIJ21117.1 AIJ21117.1 uvrD2 uvrD2 recG recG AIJ21650.1 AIJ21650.1 AIJ21711.1 AIJ21711.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (197 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (347 aa)
AIJ23643.1RecB family exonuclease. (288 aa)
AIJ24182.1DNA/RNA helicase, superfamily I. (764 aa)
AIJ24871.1Nucleic acid binding protein. (125 aa)
AIJ21118.1ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (1072 aa)
ku-2DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (285 aa)
AIJ21083.1RecB family exonuclease. (287 aa)
uvrDATP-dependent DNA helicase PcrA. (801 aa)
kuKu protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (326 aa)
AIJ21117.1ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (1069 aa)
uvrD2ATP-dependent DNA helicase. (686 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (717 aa)
AIJ21650.1DNA/RNA helicase, superfamily I. (709 aa)
AIJ21711.1Hypothetical protein. (250 aa)
Your Current Organism:
Amycolatopsis methanolica
NCBI taxonomy Id: 1068978
Other names: A. methanolica 239, Amycolatopsis methanolica 239, Amycolatopsis methanolica IFO 15065, Amycolatopsis methanolica IMSNU 20055, Amycolatopsis methanolica KCTC 9411, Amycolatopsis methanolica NCIB 11946, Amycolatopsis methanolica NRRL B-24139, Amycolatopsis methanolica str. 239, Amycolatopsis methanolica strain 239
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