node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIJ21083.1 | AIJ21117.1 | AMETH_0991 | AMETH_1025 | RecB family exonuclease. | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.443 |
AIJ21083.1 | AIJ21118.1 | AMETH_0991 | AMETH_1026 | RecB family exonuclease. | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.437 |
AIJ21117.1 | AIJ21083.1 | AMETH_1025 | AMETH_0991 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | RecB family exonuclease. | 0.443 |
AIJ21117.1 | AIJ21118.1 | AMETH_1025 | AMETH_1026 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.979 |
AIJ21117.1 | AIJ23643.1 | AMETH_1025 | AMETH_3551 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | RecB family exonuclease. | 0.423 |
AIJ21117.1 | topA-2 | AMETH_1025 | AMETH_6594 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.695 |
AIJ21117.1 | uvrD | AMETH_1025 | AMETH_0762 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase PcrA. | 0.563 |
AIJ21117.1 | uvrD2 | AMETH_1025 | AMETH_1125 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase. | 0.898 |
AIJ21118.1 | AIJ21083.1 | AMETH_1026 | AMETH_0991 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | RecB family exonuclease. | 0.437 |
AIJ21118.1 | AIJ21117.1 | AMETH_1026 | AMETH_1025 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.979 |
AIJ21118.1 | topA-2 | AMETH_1026 | AMETH_6594 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.708 |
AIJ21118.1 | uvrD | AMETH_1026 | AMETH_0762 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase PcrA. | 0.956 |
AIJ21118.1 | uvrD2 | AMETH_1026 | AMETH_1125 | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | ATP-dependent DNA helicase. | 0.988 |
AIJ21620.1 | topA-2 | AMETH_1528 | AMETH_6594 | Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.623 |
AIJ23643.1 | AIJ21117.1 | AMETH_3551 | AMETH_1025 | RecB family exonuclease. | ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. | 0.423 |
AIJ24871.1 | topA-2 | AMETH_4779 | AMETH_6594 | Nucleic acid binding protein. | DNA topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA sup [...] | 0.653 |
AIJ24871.1 | uvrD2 | AMETH_4779 | AMETH_1125 | Nucleic acid binding protein. | ATP-dependent DNA helicase. | 0.560 |
ku | ku-2 | AMETH_0281 | AMETH_5205 | Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.914 |
ku-2 | ku | AMETH_5205 | AMETH_0281 | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | Ku protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.914 |
recG | ruvA | AMETH_1550 | AMETH_2873 | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.712 |