STRINGSTRING
ligA ligA AIJ21149.1 AIJ21149.1 dnaN dnaN dnaB dnaB ssb-2 ssb-2 dnaX dnaX holB holB lig-11 lig-11 polA-2 polA-2 dnaE-2 dnaE-2 dnaQ-2 dnaQ-2 dnaQ dnaQ polA polA rnhA rnhA dnaG dnaG holA holA ssb ssb rnhB rnhB dnaN-2 dnaN-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (706 aa)
AIJ21149.1Fructose-2,6-bisphosphatase. (357 aa)
dnaNDNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (377 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (467 aa)
ssb-2Single-strand binding protein. (163 aa)
dnaXDNA polymerase III, subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (699 aa)
holBDNA polymerase III. (402 aa)
lig-11DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (508 aa)
polA-2DNA-directed DNA polymerase. (552 aa)
dnaE-2DNA polymerase III subunit alpha. (1191 aa)
dnaQ-2DNA-directed DNA polymerase. (573 aa)
dnaQDNA polymerase III subunit epsilon. (416 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (887 aa)
rnhARibonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (168 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (616 aa)
holADNA polymerase III subunit delta. (326 aa)
ssbSingle-strand binding protein. (165 aa)
rnhBRibonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (275 aa)
dnaN-2DNA polymerase III subunit beta. (359 aa)
Your Current Organism:
Amycolatopsis methanolica
NCBI taxonomy Id: 1068978
Other names: A. methanolica 239, Amycolatopsis methanolica 239, Amycolatopsis methanolica IFO 15065, Amycolatopsis methanolica IMSNU 20055, Amycolatopsis methanolica KCTC 9411, Amycolatopsis methanolica NCIB 11946, Amycolatopsis methanolica NRRL B-24139, Amycolatopsis methanolica str. 239, Amycolatopsis methanolica strain 239
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