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KAFR0B07020 KAFR0B07020 KAFR0B06490 KAFR0B06490 KAFR0B05980 KAFR0B05980 KAFR0B04370 KAFR0B04370 KAFR0B04020 KAFR0B04020 KAFR0G02390 KAFR0G02390 KAFR0B03600 KAFR0B03600 KAFR0B01530 KAFR0B01530 KAFR0B01230 KAFR0B01230 KAFR0B01130 KAFR0B01130 KAFR0B01050 KAFR0B01050 KAFR0B00830 KAFR0B00830 KAFR0B00680 KAFR0B00680 KAFR0B00350 KAFR0B00350 KAFR0A06050 KAFR0A06050 KAFR0A05540 KAFR0A05540 KAFR0A05500 KAFR0A05500 KAFR0A05050 KAFR0A05050 KAFR0A04660 KAFR0A04660 KAFR0A04170 KAFR0A04170 KAFR0A03880 KAFR0A03880 KAFR0A03820 KAFR0A03820 KAFR0A03480 KAFR0A03480 KAFR0A03220 KAFR0A03220 KAFR0A01500 KAFR0A01500 KAFR0A01050 KAFR0A01050 KAFR0L02110 KAFR0L02110 KAFR0L01820 KAFR0L01820 KAFR0L01790 KAFR0L01790 KAFR0K02160 KAFR0K02160 KAFR0K02140 KAFR0K02140 KAFR0K01650 KAFR0K01650 KAFR0K01560 KAFR0K01560 KAFR0K00960 KAFR0K00960 KAFR0J02890 KAFR0J02890 KAFR0J02820 KAFR0J02820 KAFR0J02440 KAFR0J02440 KAFR0J00840 KAFR0J00840 KAFR0J00660 KAFR0J00660 KAFR0I02500 KAFR0I02500 KAFR0I00550 KAFR0I00550 KAFR0I00210 KAFR0I00210 KAFR0H03260 KAFR0H03260 KAFR0H02770 KAFR0H02770 KAFR0H02690 KAFR0H02690 KAFR0H02150 KAFR0H02150 KAFR0H01880 KAFR0H01880 KAFR0H01480 KAFR0H01480 KAFR0H01070 KAFR0H01070 KAFR0H00930 KAFR0H00930 KAFR0H00540 KAFR0H00540 KAFR0G03670 KAFR0G03670 KAFR0G02780 KAFR0G02780 KAFR0G02610 KAFR0G02610 KAFR0A00940 KAFR0A00940 KAFR0A00930 KAFR0A00930 KAFR0G02260 KAFR0G02260 KAFR0G02230 KAFR0G02230 KAFR0G01930 KAFR0G01930 KAFR0G01130 KAFR0G01130 KAFR0G00780 KAFR0G00780 KAFR0F04040 KAFR0F04040 KAFR0F03010 KAFR0F03010 KAFR0F02290 KAFR0F02290 KAFR0F02010 KAFR0F02010 KAFR0F01390 KAFR0F01390 KAFR0F00160 KAFR0F00160 KAFR0E03960 KAFR0E03960 KAFR0E03770 KAFR0E03770 KAFR0E03620 KAFR0E03620 KAFR0E02520 KAFR0E02520 KAFR0E02390 KAFR0E02390 KAFR0E02280 KAFR0E02280 KAFR0E01350 KAFR0E01350 KAFR0E01170 KAFR0E01170 KAFR0E00880 KAFR0E00880 KAFR0E00740 KAFR0E00740 KAFR0E00690 KAFR0E00690 KAFR0E00220 KAFR0E00220 KAFR0D04890 KAFR0D04890 KAFR0D04690 KAFR0D04690 KAFR0D03740 KAFR0D03740 KAFR0D03600 KAFR0D03600 KAFR0D02970 KAFR0D02970 KAFR0D02580 KAFR0D02580 KAFR0D02260 KAFR0D02260 KAFR0D01650 KAFR0D01650 KAFR0D01510 KAFR0D01510 KAFR0D01320 KAFR0D01320 KAFR0D01200 KAFR0D01200 KAFR0D01110 KAFR0D01110 KAFR0C05760 KAFR0C05760 KAFR0C03530 KAFR0C03530 KAFR0C03400 KAFR0C03400 KAFR0C01410 KAFR0C01410 KAFR0C00990 KAFR0C00990 KAFR0C00790 KAFR0C00790 KAFR0C00640 KAFR0C00640 KAFR0C00620 KAFR0C00620 KAFR0C00240 KAFR0C00240
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KAFR0B07020Uncharacterized protein. (218 aa)
KAFR0B06490Uncharacterized protein. (66 aa)
KAFR0B05980Acetyl-coenzyme A synthetase. (679 aa)
KAFR0B04370Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (423 aa)
KAFR0B04020Uncharacterized protein. (959 aa)
KAFR0G02390Uncharacterized protein. (120 aa)
KAFR0B03600AMP-binding domain-containing protein. (699 aa)
KAFR0B01530Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (741 aa)
KAFR0B01230AA_TRNA_LIGASE_II domain-containing protein. (729 aa)
KAFR0B01130HintN domain-containing protein. (1109 aa)
KAFR0B01050BPL/LPL catalytic domain-containing protein. (686 aa)
KAFR0B00830DNA ligase. (710 aa)
KAFR0B00680CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (577 aa)
KAFR0B00350ThiF domain-containing protein. (341 aa)
KAFR0A06050Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (907 aa)
KAFR0A05540Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (605 aa)
KAFR0A05500Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1057 aa)
KAFR0A05050DNA ligase. (948 aa)
KAFR0A04660Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
KAFR0A04170Uncharacterized protein. (525 aa)
KAFR0A03880Uncharacterized protein. (1093 aa)
KAFR0A03820Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (493 aa)
KAFR0A03480Uncharacterized protein. (667 aa)
KAFR0A03220ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (508 aa)
KAFR0A01500tRNA ligase. (820 aa)
KAFR0A01050Lysine--tRNA ligase. (592 aa)
KAFR0L02110Glutamine amidotransferase type-2 domain-containing protein. (514 aa)
KAFR0L01820Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily. (535 aa)
KAFR0L01790Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1072 aa)
KAFR0K02160Glutamine synthetase. (370 aa)
KAFR0K02140AA_TRNA_LIGASE_II domain-containing protein. (532 aa)
KAFR0K01650Glutamyl-tRNA(Gln) amidotransferase subunit F, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion; Belongs to the GatF family. (161 aa)
KAFR0K01560Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1019 aa)
KAFR0K00960tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (529 aa)
KAFR0J02890Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (706 aa)
KAFR0J02820ATP-grasp domain-containing protein. (803 aa)
KAFR0J02440Uncharacterized protein. (2241 aa)
KAFR0J00840AA_TRNA_LIGASE_II domain-containing protein. (555 aa)
KAFR0J00660Tyrosine--tRNA ligase. (398 aa)
KAFR0I02500Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (440 aa)
KAFR0I00550AA_TRNA_LIGASE_II domain-containing protein. (449 aa)
KAFR0I00210Acetyl-coenzyme A synthetase. (715 aa)
KAFR0H03260Uncharacterized protein. (366 aa)
KAFR0H02770AA_TRNA_LIGASE_II domain-containing protein. (570 aa)
KAFR0H02690Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (431 aa)
KAFR0H02150Diphthami_syn_2 domain-containing protein. (702 aa)
KAFR0H01880Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (323 aa)
KAFR0H01480Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (1005 aa)
KAFR0H01070Uncharacterized protein. (466 aa)
KAFR0H00930ThiF domain-containing protein. (305 aa)
KAFR0H00540Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (380 aa)
KAFR0G03670Glutamine amidotransferase type-2 domain-containing protein. (572 aa)
KAFR0G02780AMP-binding domain-containing protein. (711 aa)
KAFR0G02610Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (794 aa)
KAFR0A00940AA_TRNA_LIGASE_II domain-containing protein. (551 aa)
KAFR0A00930AA_TRNA_LIGASE_II domain-containing protein. (673 aa)
KAFR0G02260Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1172 aa)
KAFR0G02230Uncharacterized protein. (531 aa)
KAFR0G01930Altered inheritance of mitochondria protein 41. (183 aa)
KAFR0G01130ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (543 aa)
KAFR0G00780Uncharacterized protein. (1104 aa)
KAFR0F04040Glutamine amidotransferase type-1 domain-containing protein. (1359 aa)
KAFR0F03010AA_TRNA_LIGASE_II domain-containing protein. (552 aa)
KAFR0F02290SAICAR_synt domain-containing protein. (308 aa)
KAFR0F02010Uncharacterized protein. (2211 aa)
KAFR0F01390AA_TRNA_LIGASE_II domain-containing protein. (464 aa)
KAFR0F00160Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (432 aa)
KAFR0E03960Adenylyltransferase and sulfurtransferase KAFR0E03960; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. S [...] (439 aa)
KAFR0E03770Uncharacterized protein. (107 aa)
KAFR0E03620Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family. (623 aa)
KAFR0E02520Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (331 aa)
KAFR0E02390Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (956 aa)
KAFR0E02280Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (631 aa)
KAFR0E01350Uncharacterized protein. (204 aa)
KAFR0E01170AA_TRNA_LIGASE_II domain-containing protein. (458 aa)
KAFR0E00880Uncharacterized protein. (245 aa)
KAFR0E00740Tyrosine--tRNA ligase. (467 aa)
KAFR0E00690AA_TRNA_LIGASE_II domain-containing protein. (642 aa)
KAFR0E00220UBA_e1_C domain-containing protein; Belongs to the ubiquitin-activating E1 family. (1014 aa)
KAFR0D04890Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (655 aa)
KAFR0D04690Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family. (713 aa)
KAFR0D03740tRNA-synt_1e domain-containing protein. (764 aa)
KAFR0D03600ThiF domain-containing protein. (436 aa)
KAFR0D02970Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (428 aa)
KAFR0D02580AA_TRNA_LIGASE_II domain-containing protein. (657 aa)
KAFR0D02260Uncharacterized protein. (307 aa)
KAFR0D01650AMP-binding domain-containing protein. (701 aa)
KAFR0D01510Glutamine amidotransferase type-1 domain-containing protein. (405 aa)
KAFR0D01320tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (514 aa)
KAFR0D01200Glutathione synthetase. (496 aa)
KAFR0D01110Uncharacterized protein. (458 aa)
KAFR0C05760AA_TRNA_LIGASE_II domain-containing protein. (452 aa)
KAFR0C03530B5 domain-containing protein. (595 aa)
KAFR0C03400AA_TRNA_LIGASE_II domain-containing protein. (498 aa)
KAFR0C01410Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family. (439 aa)
KAFR0C00990Uncharacterized protein. (420 aa)
KAFR0C00790ATP-synt_DE_N domain-containing protein. (158 aa)
KAFR0C00640ATP synthase subunit gamma. (309 aa)
KAFR0C00620AMP-binding domain-containing protein. (673 aa)
KAFR0C00240Uncharacterized protein. (946 aa)
Your Current Organism:
Kazachstania africana
NCBI taxonomy Id: 1071382
Other names: K. africana CBS 2517, Kazachstania africana CBS 2517
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