(30 nodes) Nervous system development network (Aspergillus wentii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1L9RNZ6	Protein kinase domain-containing protein. (509 aa)
	A0A1L9R438	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (150 aa)
	A0A1L9R562	Amidohydro-rel domain-containing protein. (440 aa)
	A0A1L9R6M3	Uncharacterized protein. (182 aa)
	A0A1L9RA56	Zn(2)-C6 fungal-type domain-containing protein. (862 aa)
	A0A1L9RAY4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (711 aa)
	A0A1L9RBV1	Uncharacterized protein. (142 aa)
	A0A1L9RE15	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (938 aa)
	A0A1L9RE72	Homeobox domain-containing protein. (562 aa)
	A0A1L9RGB8	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (747 aa)
	A0A1L9RH08	Uncharacterized protein. (199 aa)
	A0A1L9RH46	Protein kinase domain-containing protein. (541 aa)
	A0A1L9RI16	Uncharacterized protein. (521 aa)
	A0A1L9RJ03	Protein kinase domain-containing protein. (640 aa)
	A0A1L9RJK5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (852 aa)
	A0A1L9RLK6	Uncharacterized protein. (617 aa)
	A0A1L9RMU0	Amidohydro-rel domain-containing protein. (243 aa)
	A0A1L9RMZ3	Amidohydro-rel domain-containing protein. (497 aa)
	A0A1L9RNB8	Zn(2)-C6 fungal-type domain-containing protein. (605 aa)
	A0A1L9RQ80	Rad60-SLD_2 domain-containing protein. (271 aa)
	A0A1L9RQ94	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (132 aa)
	A0A1L9RT19	Ricin B-type lectin domain-containing protein. (151 aa)
	A0A1L9RTS1	Uncharacterized protein. (666 aa)
	A0A1L9RVV2	Amidohydro-rel domain-containing protein. (499 aa)
	A0A1L9RZM1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (354 aa)
	A0A1L9S0Q0	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (244 aa)
	A0A1L9S1N4	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1678 aa)
	A0A1L9S326	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (439 aa)
	A0A1L9S451	Zn(2)-C6 fungal-type domain-containing protein. (704 aa)

Your Current Organism:

Aspergillus wentii

NCBI taxonomy Id: 1073089
Other names: A. wentii DTO 134E9, Aspergillus wentii DTO 134E9

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9R438	A0A1L9RTS1	A0A1L9R438	A0A1L9RTS1	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	Uncharacterized protein.	0.470
A0A1L9RA56	A0A1L9RH08	A0A1L9RA56	A0A1L9RH08	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.462
A0A1L9RA56	A0A1L9S1N4	A0A1L9RA56	A0A1L9S1N4	Zn(2)-C6 fungal-type domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.614
A0A1L9RAY4	A0A1L9RE15	A0A1L9RAY4	A0A1L9RE15	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.975
A0A1L9RAY4	A0A1L9RH08	A0A1L9RAY4	A0A1L9RH08	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Uncharacterized protein.	0.465
A0A1L9RAY4	A0A1L9RJK5	A0A1L9RAY4	A0A1L9RJK5	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.984
A0A1L9RAY4	A0A1L9RZM1	A0A1L9RAY4	A0A1L9RZM1	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.468
A0A1L9RAY4	A0A1L9S0Q0	A0A1L9RAY4	A0A1L9S0Q0	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.872
A0A1L9RAY4	A0A1L9S1N4	A0A1L9RAY4	A0A1L9S1N4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.954
A0A1L9RAY4	A0A1L9S326	A0A1L9RAY4	A0A1L9S326	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.991
A0A1L9RE15	A0A1L9RAY4	A0A1L9RE15	A0A1L9RAY4	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.975
A0A1L9RE15	A0A1L9RGB8	A0A1L9RE15	A0A1L9RGB8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.930
A0A1L9RE15	A0A1L9RJK5	A0A1L9RE15	A0A1L9RJK5	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.997
A0A1L9RE15	A0A1L9RMZ3	A0A1L9RE15	A0A1L9RMZ3	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Amidohydro-rel domain-containing protein.	0.445
A0A1L9RE15	A0A1L9RNB8	A0A1L9RE15	A0A1L9RNB8	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Zn(2)-C6 fungal-type domain-containing protein.	0.445
A0A1L9RE15	A0A1L9RQ80	A0A1L9RE15	A0A1L9RQ80	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Rad60-SLD_2 domain-containing protein.	0.930
A0A1L9RE15	A0A1L9RZM1	A0A1L9RE15	A0A1L9RZM1	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.438
A0A1L9RE15	A0A1L9S0Q0	A0A1L9RE15	A0A1L9S0Q0	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.873
A0A1L9RE15	A0A1L9S1N4	A0A1L9RE15	A0A1L9S1N4	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.871
A0A1L9RE15	A0A1L9S326	A0A1L9RE15	A0A1L9S326	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.997