25 items (Penicilliopsis zonata) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	A0A1L9SJM3	NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (308 aa)
	A0A1L9S575	Uncharacterized protein. (222 aa)
	A0A1L9S998	Uncharacterized protein. (1402 aa)
	A0A1L9S9B0	Uncharacterized protein. (614 aa)
	A0A1L9S9B3	GIDA_assoc domain-containing protein. (685 aa)
	A0A1L9S9J7	Uncharacterized protein. (334 aa)
	A0A1L9SA51	DPH-type MB domain-containing protein. (463 aa)
	A0A1L9SAL0	Methyltransf_11 domain-containing protein. (238 aa)
	A0A1L9SB57	Uncharacterized protein. (394 aa)
	A0A1L9SBG5	Uncharacterized protein. (245 aa)
	A0A1L9SBN6	Uncharacterized protein. (193 aa)
	A0A1L9SC51	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1333 aa)
	A0A1L9SES1	Uncharacterized protein. (266 aa)
	A0A1L9SHV8	Uncharacterized protein. (263 aa)
	A0A1L9SJM2	Uncharacterized protein. (126 aa)
	NCS6	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (432 aa)
	CFD1	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (335 aa)
	A0A1L9SNK4	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (579 aa)
	A0A1L9SNN1	Uncharacterized protein. (139 aa)
	A0A1L9SU97	Uncharacterized protein. (209 aa)
	uba4	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (526 aa)
	A0A1L9SUR5	Uncharacterized protein. (394 aa)
	NCS2	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (366 aa)
	NBP35	Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (343 aa)
	A0A1L9SXF1	Uncharacterized protein. (348 aa)

Your Current Organism:

Penicilliopsis zonata

NCBI taxonomy Id: 1073090
Other names: Aspergillus zonatus CBS 506.65, P. zonata CBS 506.65, Penicilliopsis zonata CBS 506.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9S575	A0A1L9SXF1	A0A1L9S575	A0A1L9SXF1	Uncharacterized protein.	Uncharacterized protein.	0.861
A0A1L9S575	NCS2	A0A1L9S575	A0A1L9SV92	Uncharacterized protein.	Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.	0.436
A0A1L9S575	NCS6	A0A1L9S575	A0A1L9SL20	Uncharacterized protein.	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.	0.463
A0A1L9S575	uba4	A0A1L9S575	A0A1L9SUI5	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.936
A0A1L9S998	A0A1L9S9J7	A0A1L9S998	A0A1L9S9J7	Uncharacterized protein.	Uncharacterized protein.	0.950
A0A1L9S998	A0A1L9SA51	A0A1L9S998	A0A1L9SA51	Uncharacterized protein.	DPH-type MB domain-containing protein.	0.717
A0A1L9S998	A0A1L9SAL0	A0A1L9S998	A0A1L9SAL0	Uncharacterized protein.	Methyltransf_11 domain-containing protein.	0.437
A0A1L9S998	A0A1L9SB57	A0A1L9S998	A0A1L9SB57	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A1L9S998	A0A1L9SBG5	A0A1L9S998	A0A1L9SBG5	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A1L9S998	A0A1L9SBN6	A0A1L9S998	A0A1L9SBN6	Uncharacterized protein.	Uncharacterized protein.	0.681
A0A1L9S998	A0A1L9SC51	A0A1L9S998	A0A1L9SC51	Uncharacterized protein.	Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family.	0.994
A0A1L9S998	A0A1L9SES1	A0A1L9S998	A0A1L9SES1	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A1L9S998	A0A1L9SNK4	A0A1L9S998	A0A1L9SNK4	Uncharacterized protein.	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation.	0.985
A0A1L9S998	A0A1L9SNN1	A0A1L9S998	A0A1L9SNN1	Uncharacterized protein.	Uncharacterized protein.	0.863
A0A1L9S998	A0A1L9SU97	A0A1L9S998	A0A1L9SU97	Uncharacterized protein.	Uncharacterized protein.	0.926
A0A1L9S998	A0A1L9SUR5	A0A1L9S998	A0A1L9SUR5	Uncharacterized protein.	Uncharacterized protein.	0.975
A0A1L9S998	NCS6	A0A1L9S998	A0A1L9SL20	Uncharacterized protein.	Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.	0.580
A0A1L9S998	uba4	A0A1L9S998	A0A1L9SUI5	Uncharacterized protein.	Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]	0.567
A0A1L9S9B0	A0A1L9S9B3	A0A1L9S9B0	A0A1L9S9B3	Uncharacterized protein.	GIDA_assoc domain-containing protein.	0.989
A0A1L9S9B0	A0A1L9SBN6	A0A1L9S9B0	A0A1L9SBN6	Uncharacterized protein.	Uncharacterized protein.	0.540