(22 nodes) Iron-sulfur cluster assembly network (Penicilliopsis zonata)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	A0A1L9SG69	Uncharacterized protein. (1063 aa)
	A0A1L9SG85	Uncharacterized protein. (526 aa)
	A0A1L9SKP6	Nfu_N domain-containing protein. (259 aa)
	A0A1L9SMQ0	2Fe-2S ferredoxin-type domain-containing protein. (212 aa)
	CFD1	Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (335 aa)
	TAH18	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (872 aa)
	NBP35	Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (343 aa)
	A0A1L9SGF5	J domain-containing protein. (182 aa)
	A0A1L9SGQ9	Uncharacterized protein. (190 aa)
	A0A1L9S8F1	Uncharacterized protein; Belongs to the complex I LYR family. (112 aa)
	A0A1L9SA97	Uncharacterized protein. (203 aa)
	A0A1L9S9X5	Uncharacterized protein. (325 aa)
	A0A1L9SA39	Uncharacterized protein. (561 aa)
	A0A1L9SQ75	Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family. (602 aa)
	A0A1L9S9S9	Uncharacterized protein. (193 aa)
	DRE2	Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (308 aa)
	CIA1	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (400 aa)
	A0A1L9SB01	Aminotran_5 domain-containing protein. (509 aa)
	A0A1L9SC29	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (193 aa)
	A0A1L9S8F9	Uncharacterized protein. (764 aa)
	A0A1L9SHZ6	Fe-S_biosyn domain-containing protein. (124 aa)
	A0A1L9SKA1	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (137 aa)

Your Current Organism:

Penicilliopsis zonata

NCBI taxonomy Id: 1073090
Other names: Aspergillus zonatus CBS 506.65, P. zonata CBS 506.65, Penicilliopsis zonata CBS 506.65

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1L9S8F1	A0A1L9S8F9	A0A1L9S8F1	A0A1L9S8F9	Uncharacterized protein; Belongs to the complex I LYR family.	Uncharacterized protein.	0.899
A0A1L9S8F1	A0A1L9SA97	A0A1L9S8F1	A0A1L9SA97	Uncharacterized protein; Belongs to the complex I LYR family.	Uncharacterized protein.	0.963
A0A1L9S8F1	A0A1L9SB01	A0A1L9S8F1	A0A1L9SB01	Uncharacterized protein; Belongs to the complex I LYR family.	Aminotran_5 domain-containing protein.	0.979
A0A1L9S8F1	A0A1L9SC29	A0A1L9S8F1	A0A1L9SC29	Uncharacterized protein; Belongs to the complex I LYR family.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.961
A0A1L9S8F1	A0A1L9SHZ6	A0A1L9S8F1	A0A1L9SHZ6	Uncharacterized protein; Belongs to the complex I LYR family.	Fe-S_biosyn domain-containing protein.	0.461
A0A1L9S8F1	A0A1L9SKA1	A0A1L9S8F1	A0A1L9SKA1	Uncharacterized protein; Belongs to the complex I LYR family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.890
A0A1L9S8F1	A0A1L9SKP6	A0A1L9S8F1	A0A1L9SKP6	Uncharacterized protein; Belongs to the complex I LYR family.	Nfu_N domain-containing protein.	0.495
A0A1L9S8F1	A0A1L9SMQ0	A0A1L9S8F1	A0A1L9SMQ0	Uncharacterized protein; Belongs to the complex I LYR family.	2Fe-2S ferredoxin-type domain-containing protein.	0.845
A0A1L9S8F1	A0A1L9SQ75	A0A1L9S8F1	A0A1L9SQ75	Uncharacterized protein; Belongs to the complex I LYR family.	Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.	0.438
A0A1L9S8F1	CIA1	A0A1L9S8F1	A0A1L9SR29	Uncharacterized protein; Belongs to the complex I LYR family.	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.	0.467
A0A1L9S8F1	DRE2	A0A1L9S8F1	A0A1L9S8Z0	Uncharacterized protein; Belongs to the complex I LYR family.	Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]	0.449
A0A1L9S8F9	A0A1L9S8F1	A0A1L9S8F9	A0A1L9S8F1	Uncharacterized protein.	Uncharacterized protein; Belongs to the complex I LYR family.	0.899
A0A1L9S8F9	A0A1L9SA97	A0A1L9S8F9	A0A1L9SA97	Uncharacterized protein.	Uncharacterized protein.	0.956
A0A1L9S8F9	A0A1L9SB01	A0A1L9S8F9	A0A1L9SB01	Uncharacterized protein.	Aminotran_5 domain-containing protein.	0.975
A0A1L9S8F9	A0A1L9SC29	A0A1L9S8F9	A0A1L9SC29	Uncharacterized protein.	Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.955
A0A1L9S8F9	A0A1L9SKA1	A0A1L9S8F9	A0A1L9SKA1	Uncharacterized protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.887
A0A1L9S8F9	A0A1L9SKP6	A0A1L9S8F9	A0A1L9SKP6	Uncharacterized protein.	Nfu_N domain-containing protein.	0.418
A0A1L9S8F9	A0A1L9SMQ0	A0A1L9S8F9	A0A1L9SMQ0	Uncharacterized protein.	2Fe-2S ferredoxin-type domain-containing protein.	0.817
A0A1L9S8F9	A0A1L9SQ75	A0A1L9S8F9	A0A1L9SQ75	Uncharacterized protein.	Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.	0.408
A0A1L9S8F9	CIA1	A0A1L9S8F9	A0A1L9SR29	Uncharacterized protein.	Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.	0.467