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A0A1L9SD61 A0A1L9SD61 GUF1 GUF1 COQ3 COQ3 A0A1L9S9M6 A0A1L9S9M6 COQ4 COQ4 A0A1L9S8E0 A0A1L9S8E0 A0A1L9S8C3 A0A1L9S8C3 A0A1L9S7E4 A0A1L9S7E4 COQ6 COQ6 A0A1L9SPX1 A0A1L9SPX1 A0A1L9SPR9 A0A1L9SPR9 A0A1L9SNN2 A0A1L9SNN2 COQ7 COQ7 A0A1L9S7A9 A0A1L9S7A9 A0A1L9S4A3 A0A1L9S4A3 A0A1L9SC48 A0A1L9SC48 A0A1L9SLD5 A0A1L9SLD5 A0A1L9SGT7 A0A1L9SGT7 A0A1L9SCD0 A0A1L9SCD0 A0A1L9SF67 A0A1L9SF67 A0A1L9SW53 A0A1L9SW53 A0A1L9SC08 A0A1L9SC08 A0A1L9SBY3 A0A1L9SBY3 PSD1 PSD1 A0A1L9SEQ3 A0A1L9SEQ3 A0A1L9SE36 A0A1L9SE36 A0A1L9SUM9 A0A1L9SUM9 A0A1L9SUJ1 A0A1L9SUJ1 A0A1L9STX9 A0A1L9STX9 A0A1L9STK9 A0A1L9STK9 A0A1L9SS01 A0A1L9SS01 A0A1L9SRX3 A0A1L9SRX3 A0A1L9SRU8 A0A1L9SRU8 A0A1L9SR95 A0A1L9SR95 A0A1L9SQY2 A0A1L9SQY2 A0A1L9SQT8 A0A1L9SQT8 A0A1L9SQK1 A0A1L9SQK1 COQ5 COQ5
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
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A0A1L9SD61Magnesium transporter. (399 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (664 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (349 aa)
A0A1L9S9M6ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (169 aa)
COQ4Ubiquinone biosynthesis protein COQ4, mitochondrial; Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides; Belongs to the COQ4 family. (285 aa)
A0A1L9S8E0SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (322 aa)
A0A1L9S8C3Cytochrome c oxidase subunit 6A, mitochondrial. (133 aa)
A0A1L9S7E4Magnesium transporter. (585 aa)
COQ6Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. (512 aa)
A0A1L9SPX1NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (189 aa)
A0A1L9SPR9NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (498 aa)
A0A1L9SNN2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (142 aa)
COQ75-demethoxyubiquinone hydroxylase, mitochondrial; Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6- methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. (237 aa)
A0A1L9S7A9Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (179 aa)
A0A1L9S4A3Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (127 aa)
A0A1L9SC48Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (290 aa)
A0A1L9SLD5COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (62 aa)
A0A1L9SGT7Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c. (571 aa)
A0A1L9SCD0Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (104 aa)
A0A1L9SF67Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (164 aa)
A0A1L9SW53Cytochrome c oxidase assembly protein COX20, mitochondrial; Involved in the assembly of the cytochrome c oxidase complex. Belongs to the COX20 family. (203 aa)
A0A1L9SC08MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (1904 aa)
A0A1L9SBY3Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (103 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (546 aa)
A0A1L9SEQ3COX assembly mitochondrial protein; Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration; Belongs to the CMC family. (124 aa)
A0A1L9SE36MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (251 aa)
A0A1L9SUM9Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (274 aa)
A0A1L9SUJ1Sensitive to high expression protein 9, mitochondrial; Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. (509 aa)
A0A1L9STX9Prohibitin. (305 aa)
A0A1L9STK9Mitochondrial inner membrane protease ATP23; Has a dual role in the assembly of mitochondrial ATPase. Belongs to the peptidase M76 family. (239 aa)
A0A1L9SS01NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (159 aa)
A0A1L9SRX3Prohibitin. (277 aa)
A0A1L9SRU8MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (91 aa)
A0A1L9SR95Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (513 aa)
A0A1L9SQY24-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. (420 aa)
A0A1L9SQT8MICOS complex subunit MIC12; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (125 aa)
A0A1L9SQK1Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix; Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (330 aa)
COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). (311 aa)
Your Current Organism:
Penicilliopsis zonata
NCBI taxonomy Id: 1073090
Other names: Aspergillus zonatus CBS 506.65, P. zonata CBS 506.65, Penicilliopsis zonata CBS 506.65
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