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| | SEJ37824.1 | Thiosulfate/3-mercaptopyruvate sulfurtransferase. (286 aa) |
| | SEJ36303.1 | Acyl-CoA dehydrogenase. (395 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (411 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (296 aa) |
| | SEJ35238.1 | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase. (289 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (307 aa) |
| | SEJ34911.1 | 3-hydroxyacyl-CoA dehydrogenase /Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (655 aa) |
| | SEJ32856.1 | Acetyl-coenzyme A synthetase. (663 aa) |
| | SEJ31876.1 | UDPglucose 6-dehydrogenase. (431 aa) |
| | SEJ31466.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa) |
| | glmS-2 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (598 aa) |
| | SEJ30545.1 | Isochorismate synthase. (480 aa) |
| | ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (581 aa) |
| | SEJ27900.1 | GH3 auxin-responsive promoter. (411 aa) |
| | SEJ28090.1 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (463 aa) |
| | SEJ28030.1 | Agmatinase; Belongs to the arginase family. (270 aa) |
| | SEJ26618.1 | Homoserine dehydrogenase. (319 aa) |
| | SEJ24623.1 | Phosphoribosyl 1,2-cyclic phosphate phosphodiesterase. (292 aa) |
| | SEJ24923.1 | 3-ketoacyl-CoA thiolase. (377 aa) |
| | SEJ24908.1 | Kynurenine formamidase. (224 aa) |
| | SEJ24886.1 | Long-chain acyl-CoA synthetase. (684 aa) |
| | SEJ24704.1 | Putative hydrolase of the HAD superfamily. (220 aa) |
| | SEJ23062.1 | Coenzyme F420-0 gamma-glutamyl ligase. (256 aa) |
| | SEJ22330.1 | Succinyl-diaminopimelate desuccinylase. (413 aa) |
| | SEJ22174.1 | Selenocysteine lyase/Cysteine desulfurase. (372 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (291 aa) |
| | SEJ19691.1 | L-proline dehydrogenase. (294 aa) |
| | SEJ19976.1 | GMP synthase (glutamine-hydrolysing). (237 aa) |
| | SEJ19897.1 | Aldehyde dehydrogenase (NAD+). (503 aa) |
| | SEJ18843.1 | L-lactate dehydrogenase complex protein LldG. (171 aa) |
| | SEJ18805.1 | FAD/FMN-containing dehydrogenase. (1021 aa) |
| | SEJ18993.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (754 aa) |
| | gap-2 | Glyceraldehyde 3-phosphate dehydrogenase (NAD(P)+). (342 aa) |
| | SEJ18951.1 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (300 aa) |
| | SEJ16068.1 | Acyl dehydratase. (150 aa) |
| | SEJ15974.1 | Acetyl-CoA carboxylase, carboxyltransferase component. (596 aa) |
| | SEJ15938.1 | Glutamine synthetase. (456 aa) |
| | carB | Carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. (1073 aa) |
| | SEJ15246.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (233 aa) |
| | SEJ14840.1 | Acyl-CoA dehydrogenase. (382 aa) |
| | SEJ13639.1 | Fructose-bisphosphate aldolase. (262 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (270 aa) |
| | SEJ13929.1 | NADP-dependent 3-hydroxy acid dehydrogenase YdfG. (233 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (328 aa) |
| | SEJ12913.1 | Translation initiation factor eIF-2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (282 aa) |
| | SEJ12853.1 | NADP-dependent 3-hydroxy acid dehydrogenase YdfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (338 aa) |
| | SEJ12237.1 | Selenocysteine lyase/Cysteine desulfurase. (375 aa) |
| | SEJ11364.1 | SSU ribosomal protein S6P modification protein. (291 aa) |
| | SEJ10099.1 | Thiosulfate/3-mercaptopyruvate sulfurtransferase. (84 aa) |
| | SEJ08263.1 | Allosteric NADP-dependent malic enzyme. (750 aa) |
| | SEJ08692.1 | Broad specificity phosphatase PhoE. (205 aa) |
| | SEJ08396.1 | Putative hydrolase of the HAD superfamily. (223 aa) |
| | SEJ07398.1 | Putative mRNA 3-end processing factor. (790 aa) |
| | SEJ05947.1 | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (239 aa) |
| | SEJ05928.1 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (305 aa) |
| | SEJ05729.1 | Citrate lyase subunit beta / citryl-CoA lyase. (298 aa) |
| | SEJ05668.1 | Galactonate dehydratase. (383 aa) |
| | SEJ05508.1 | Galactonate dehydratase. (383 aa) |
| | nadA | Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (377 aa) |
| | SEJ05320.1 | Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (275 aa) |
| | SEJ05253.1 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (168 aa) |
| | mptE | Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (241 aa) |
| | SEJ05083.1 | Dihydropteroate synthase. (366 aa) |
| | SEJ00879.1 | Probable phosphoglycerate mutase. (209 aa) |
| | SEJ00018.1 | 4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa) |
| | SEI99941.1 | Allosteric NADP-dependent malic enzyme. (749 aa) |
| | gap | Glyceraldehyde 3-phosphate dehydrogenase (NAD(P)+). (355 aa) |
| | SEI99901.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa) |
| | SEI99805.1 | D-galactarolactone cycloisomerase. (375 aa) |
| | SEI99724.1 | 2-methylcitrate dehydratase PrpD. (450 aa) |
| | SEI99669.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (775 aa) |
| | cofD | LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (332 aa) |
| | SEI99433.1 | Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa) |
| | SEI99401.1 | Aspartate-semialdehyde dehydrogenase. (346 aa) |
| | SEI98811.1 | F420-dependent oxidoreductase, G6PDH family. (210 aa) |
| | SEI98107.1 | Acetylornithine deacetylase. (365 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (460 aa) |
| | SEI97926.1 | Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (350 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (406 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (430 aa) |
| | SEI97491.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) |
| | SEI97113.1 | Acyl dehydratase. (209 aa) |
| | SEI96826.1 | Isocitrate dehydrogenase (NADP). (420 aa) |
| | thrS | threonyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (643 aa) |
| | SEI95657.1 | propionyl-CoA carboxylase carboxyltransferase subunit. (516 aa) |
| | SEI95464.1 | methylmalonyl-CoA mutase, C-terminal domain. (139 aa) |
| | SEI94542.1 | Citrate lyase subunit beta / citryl-CoA lyase. (279 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa) |
| | SEI92979.1 | Thiosulfate/3-mercaptopyruvate sulfurtransferase. (268 aa) |
| | SEI92955.1 | Thiosulfate/3-mercaptopyruvate sulfurtransferase. (288 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa) |
| | panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (269 aa) |
| | SEI92404.1 | Asparagine synthase (glutamine-hydrolysing). (389 aa) |
| | gatC | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (92 aa) |
| | aroB | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (387 aa) |
| | aroA-2 | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (285 aa) |
| | trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (412 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (255 aa) |
| | SEI90302.1 | Arginine decarboxylase. (159 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (554 aa) |
| | hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) |
| | SEI87643.1 | L-threonine O-3-phosphate decarboxylase. (334 aa) |
| | SEI87570.1 | FMN phosphatase YigB, HAD superfamily. (213 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (451 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (284 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (247 aa) |
| | SEI86909.1 | Aldehyde dehydrogenase (acceptor). (508 aa) |
| | SEI84925.1 | Coenzyme F420-0:L-glutamate ligase / coenzyme F420-1:gamma-L-glutamate ligase. (256 aa) |
| | SEI84694.1 | Maltose O-acetyltransferase. (322 aa) |
| | gatD | glutamyl-tRNA(Gln) amidotransferase subunit D; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (428 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (504 aa) |
| | SEI83997.1 | 2-isopropylmalate synthase. (345 aa) |
| | SEI83954.1 | Acetolactate synthase, small subunit. (233 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) |
| | SEI83842.1 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit. (210 aa) |
| | SEI82911.1 | Phosphoenolpyruvate carboxylase, type 1. (897 aa) |
| | SEI83814.1 | 3-isopropylmalate dehydrogenase. (327 aa) |
| | SEI83620.1 | Gluconate dehydratase. (411 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (384 aa) |
| | SEI82867.1 | Aspartate aminotransferase. (375 aa) |
| | cbiA | Hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) /cobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (434 aa) |
| | mptD | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (113 aa) |
| | SEI85332.1 | Acyl-CoA hydrolase. (147 aa) |
| | SEI80188.1 | Cysteine desulfurase. (425 aa) |
| | SEI80091.1 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (161 aa) |
| | SEI80005.1 | 6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. (299 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (356 aa) |
| | SEI78345.1 | Phosphoserine phosphatase. (217 aa) |
| | SEI79236.1 | Dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (467 aa) |
| | SEI79079.1 | Glyoxylase, beta-lactamase superfamily II. (207 aa) |
| | pdxT | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (203 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase. (103 aa) |
| | SEI78948.1 | Prephenate dehydratase. (270 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (888 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta subunit. (583 aa) |
| | SEI81210.1 | phenylalanyl-tRNA synthetase, alpha subunit. (501 aa) |
| | SEI81187.1 | Maltose O-acetyltransferase. (181 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (535 aa) |
| | SEI78469.1 | Malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. (304 aa) |
| | lipA | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (310 aa) |
| | SEI80633.1 | Pyruvate dehydrogenase E1 component alpha subunit. (367 aa) |
| | SEI80608.1 | Pyruvate dehydrogenase E1 component beta subunit. (339 aa) |
| | SEI80504.1 | Dihydrolipoamide dehydrogenase. (474 aa) |
| | hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (122 aa) |
| | SEI76048.1 | Anthranilate synthase component 2. (217 aa) |
| | trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (535 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (215 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) |
| | SEI75450.1 | acetyl-CoA C-acetyltransferase. (388 aa) |
| | SEI75212.1 | Branched chain amino acid aminotransferase apoenzyme; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (303 aa) |
| | SEI75171.1 | Aminodeoxychorismate synthase, subunit I. (524 aa) |
| | aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (267 aa) |
| | dtdA | D-aminoacyl-tRNA deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (459 aa) |
| | SEI74822.1 | L-threonine synthase. (397 aa) |
| | hisS | histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. (432 aa) |
| | carA | Carbamoyl-phosphate synthase small subunit; Belongs to the CarA family. (354 aa) |
| | cysS | cysteinyl-tRNA synthetase. (492 aa) |
| | SEI71858.1 | Acyl dehydratase. (147 aa) |
| | fumC | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa) |
| | SEI71003.1 | Glutamate synthase (NADPH/NADH) large chain. (1515 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (489 aa) |
| | SEI70690.1 | Glyoxylase, beta-lactamase superfamily II. (269 aa) |
| | SEI70202.1 | 2-dehydro-3-deoxyglucarate aldolase. (261 aa) |
| | SEI72168.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (339 aa) |
| | SEI72147.1 | Methionine synthase (B12-independent). (357 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (422 aa) |
| | SEI66593.1 | Fructose-bisphosphate aldolase, class II. (330 aa) |
| | SEI66491.1 | Ornithine cyclodeaminase. (332 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (922 aa) |
| | SEI66402.1 | Fructose-bisphosphate aldolase. (274 aa) |
| | SEI66370.1 | 3-hydroxyacyl-CoA dehydrogenase. (287 aa) |
| | SEI66291.1 | methylmalonyl-CoA mutase. (558 aa) |
| | SEI66045.1 | Aminobenzoyl-glutamate utilization protein A. (430 aa) |
| | SEI68358.1 | acetyl-CoA C-acetyltransferase. (384 aa) |
| | SEI67306.1 | Phosphopantothenate-cysteine ligase. (394 aa) |
| | guaAA | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. (182 aa) |
| | SEI62163.1 | Agmatinase; Belongs to the arginase family. (368 aa) |
| | lysS | lysyl-tRNA synthetase, class I; Belongs to the class-I aminoacyl-tRNA synthetase family. (555 aa) |
| | SEI61706.1 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (526 aa) |
| | cobQ | Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (509 aa) |
| | SEI61476.1 | Prephenate dehydrogenase. (252 aa) |
| | SEI63959.1 | Lactoylglutathione lyase. (264 aa) |
| | SEI63691.1 | Uncharacterized coiled-coil protein, contains DUF342 domain. (303 aa) |
| | ileS | Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1052 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (434 aa) |
| | SEI58505.1 | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). (245 aa) |
| | hisC | Histidinol phosphate aminotransferase apoenzyme. (362 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa) |
| | SEI58220.1 | FAD/FMN-containing dehydrogenase. (1028 aa) |
| | SEI58042.1 | Aspartate aminotransferase. (354 aa) |
| | glmS | Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (605 aa) |
| | SEI59744.1 | N-carbamoyl-L-amino-acid hydrolase. (423 aa) |
| | SEI59523.1 | 2-haloacid dehalogenase. (227 aa) |
| | SEI59295.1 | Chorismate mutase. (93 aa) |
| | aroK | Shikimate kinase. (303 aa) |
| | pyrB | Aspartate carbamoyltransferase. (306 aa) |
| | SEI53428.1 | Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (533 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (225 aa) |
| | cofC | Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (207 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (297 aa) |
| | SEI53008.1 | Anthranilate phosphoribosyltransferase. (353 aa) |
| | SEI52986.1 | Tyrosine decarboxylase / aspartate 1-decarboxylase. (337 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (702 aa) |
| | SEI52779.1 | Aspartate aminotransferase. (383 aa) |
| | SEI55280.1 | acetyl-CoA synthetase. (547 aa) |
| | SEI55127.1 | Succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase. (470 aa) |
| | SEI55044.1 | Acyl-CoA hydrolase. (160 aa) |
| | SEI54608.1 | Glycine dehydrogenase (decarboxylating) beta subunit. (475 aa) |
| | SEI54590.1 | Glycine dehydrogenase (decarboxylating) alpha subunit. (442 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (505 aa) |
| | SEI52303.1 | Dihydropteroate synthase. (849 aa) |
| | SEI53802.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (584 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) |
| | SEI47853.1 | glycyl-tRNA synthetase. (597 aa) |
| | argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) |
| | argH | Argininosuccinate lyase. (493 aa) |
| | SEI47781.1 | Alpha-aminoadipate carrier protein LysW. (56 aa) |
| | SEI47766.1 | L-2-aminoadipate N-acetyltransferase. (294 aa) |
| | lysY | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (356 aa) |
| | lysJ | acetylornithine/LysW-gamma-L-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (378 aa) |
| | lysK | Acetylornithine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine. (373 aa) |
| | SEI47702.1 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (294 aa) |
| | SEI47578.1 | O-acetylhomoserine (thiol)-lyase. (427 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (417 aa) |
| | SEI47553.1 | O-acetylhomoserine sulfhydrylase. (429 aa) |
| | SEI47448.1 | Phosphoserine aminotransferase, putative. (395 aa) |
| | argS | arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (585 aa) |
| | SEI47045.1 | leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (958 aa) |
| | ala | L-alanine dehydrogenase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily. (338 aa) |
| | SEI46973.1 | L-threonine ammonia-lyase. (403 aa) |
| | ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (314 aa) |
| | hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa) |
| | SEI49432.1 | Cysteine synthase. (303 aa) |
| | SEI49388.1 | Glutamate dehydrogenase (NADP); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (417 aa) |
| | SEI49204.1 | Putative intracellular protease/amidase. (230 aa) |
| | SEI49108.1 | Glyceraldehyde-3-phosphate dehydrogenase [NAD(P)+]. (463 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase. (198 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (244 aa) |
| | SEI48484.1 | uroporphyrinogen-III synthase. (248 aa) |
| | SEI48421.1 | Serine O-acetyltransferase. (288 aa) |
