STRINGSTRING
ilvE ilvE SEI54154.1 SEI54154.1 SEI55144.1 SEI55144.1 SEI52986.1 SEI52986.1 SEI59820.1 SEI59820.1 SEI62949.1 SEI62949.1 SEI62964.1 SEI62964.1 SEI67306.1 SEI67306.1 SEI65833.1 SEI65833.1 SEI75212.1 SEI75212.1 ilvC ilvC SEI83954.1 SEI83954.1 SEI83973.1 SEI83973.1 SEI86909.1 SEI86909.1 panB panB SEJ19897.1 SEJ19897.1 ilvD ilvD
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvEBranched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (314 aa)
SEI54154.1Pantetheine-phosphate adenylyltransferase. (162 aa)
SEI55144.1Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (528 aa)
SEI52986.1Tyrosine decarboxylase / aspartate 1-decarboxylase. (337 aa)
SEI59820.1Dihydropyrimidinase. (464 aa)
SEI62949.1Pantothenate synthetase. (249 aa)
SEI62964.1Pantothenate kinase. (283 aa)
SEI67306.1Phosphopantothenate-cysteine ligase. (394 aa)
SEI65833.1Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (189 aa)
SEI75212.1Branched chain amino acid aminotransferase apoenzyme; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (303 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa)
SEI83954.1Acetolactate synthase, small subunit. (233 aa)
SEI83973.1Acetolactate synthase, large subunit. (590 aa)
SEI86909.1Aldehyde dehydrogenase (acceptor). (508 aa)
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (269 aa)
SEJ19897.1Aldehyde dehydrogenase (NAD+). (503 aa)
ilvDDihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (581 aa)
Your Current Organism:
Halohasta litchfieldiae
NCBI taxonomy Id: 1073996
Other names: CGMCC 1.12394, DSM 22187, H. litchfieldiae, Halobacteriaceae archaeon tADL, Halohasta litchfieldiae Mou et al. 2013, JCM 15066, halophilic archaeon True-ADL, strain tADL
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