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SEI48112.1 | Lipid kinase, YegS/Rv2252/BmrU family. (305 aa) | ||||
SEI48421.1 | Serine O-acetyltransferase. (288 aa) | ||||
hemL | Glutamate-1-semialdehyde 2,1-aminomutase. (445 aa) | ||||
SEI48459.1 | Hydroxymethylbilane synthase. (381 aa) | ||||
SEI48468.1 | uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (273 aa) | ||||
SEI48484.1 | uroporphyrinogen-III synthase. (248 aa) | ||||
hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (244 aa) | ||||
hisB | Imidazoleglycerol-phosphate dehydratase. (198 aa) | ||||
SEI49005.1 | Choline dehydrogenase. (540 aa) | ||||
SEI49432.1 | Cysteine synthase. (303 aa) | ||||
SEI49507.1 | Phenazine biosynthesis protein PhzF family. (306 aa) | ||||
prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (286 aa) | ||||
hisG | ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (281 aa) | ||||
rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (230 aa) | ||||
SEI46927.1 | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase. (207 aa) | ||||
ilvE | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (314 aa) | ||||
SEI46973.1 | L-threonine ammonia-lyase. (403 aa) | ||||
SEI46654.1 | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (228 aa) | ||||
SEI47160.1 | Aspartate kinase; Belongs to the aspartokinase family. (392 aa) | ||||
SEI47196.1 | Fructokinase. (317 aa) | ||||
purO | IMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (197 aa) | ||||
metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (417 aa) | ||||
SEI47702.1 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (294 aa) | ||||
lysJ | acetylornithine/LysW-gamma-L-lysine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily. (378 aa) | ||||
lysZ | N-acetylglutamate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily. (315 aa) | ||||
lysY | N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily. (356 aa) | ||||
argH | Argininosuccinate lyase. (493 aa) | ||||
argG | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (408 aa) | ||||
glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa) | ||||
SEI53802.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (584 aa) | ||||
purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (429 aa) | ||||
SEI54266.1 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (348 aa) | ||||
purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (505 aa) | ||||
gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) | ||||
gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) | ||||
SEI54590.1 | Glycine dehydrogenase (decarboxylating) alpha subunit. (442 aa) | ||||
SEI54608.1 | Glycine dehydrogenase (decarboxylating) beta subunit. (475 aa) | ||||
SEI55144.1 | Acetolactate synthase-1/2/3 large subunit; Belongs to the TPP enzyme family. (528 aa) | ||||
purM | Phosphoribosylformylglycinamidine cyclo-ligase. (329 aa) | ||||
adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (205 aa) | ||||
SEI55280.1 | acetyl-CoA synthetase. (547 aa) | ||||
SEI55651.1 | Aconitase. (656 aa) | ||||
purE | 5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (207 aa) | ||||
purK | 5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (395 aa) | ||||
ribH | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (134 aa) | ||||
SEI52779.1 | Aspartate aminotransferase. (383 aa) | ||||
SEI52986.1 | Tyrosine decarboxylase / aspartate 1-decarboxylase. (337 aa) | ||||
SEI53008.1 | Anthranilate phosphoribosyltransferase. (353 aa) | ||||
purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (341 aa) | ||||
purS | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (87 aa) | ||||
purQ | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (225 aa) | ||||
SEI53514.1 | Diphosphomevalonate decarboxylase. (327 aa) | ||||
mat | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP; Belongs to the AdoMet synthase 2 family. (400 aa) | ||||
aroK | Shikimate kinase. (303 aa) | ||||
SEI59295.1 | Chorismate mutase. (93 aa) | ||||
SEI59504.1 | Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family. (646 aa) | ||||
SEI58277.1 | (1->4)-alpha-D-glucan branching enzyme. (495 aa) | ||||
tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa) | ||||
SEI58396.1 | Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (181 aa) | ||||
hisC | Histidinol phosphate aminotransferase apoenzyme. (362 aa) | ||||
ctaB | Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (448 aa) | ||||
SEI61476.1 | Prephenate dehydrogenase. (252 aa) | ||||
SEI62620.1 | Nucleoside diphosphate kinase; Belongs to the NDK family. (151 aa) | ||||
SEI68275.1 | Archaetidylserine synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (245 aa) | ||||
SEI68358.1 | acetyl-CoA C-acetyltransferase. (384 aa) | ||||
SEI68481.1 | Lycopene cyclase domain-containing protein. (245 aa) | ||||
fbp | D-fructose 1,6-bisphosphatase; Belongs to the FBPase class 1 family. (294 aa) | ||||
SEI66402.1 | Fructose-bisphosphate aldolase. (274 aa) | ||||
fbp-2 | D-fructose 1,6-bisphosphatase; Belongs to the FBPase class 1 family. (291 aa) | ||||
SEI67002.1 | Myo-inositol-1(or 4)-monophosphatase. (269 aa) | ||||
hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (422 aa) | ||||
SEI69831.1 | Farnesyl-diphosphate farnesyltransferase. (359 aa) | ||||
SEI72017.1 | Glycerate 2-kinase. (446 aa) | ||||
SEI72147.1 | Methionine synthase (B12-independent). (357 aa) | ||||
SEI72168.1 | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase. (339 aa) | ||||
SEI70188.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa) | ||||
mvk | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (338 aa) | ||||
SEI71054.1 | STE24 endopeptidase. (432 aa) | ||||
SEI69921.1 | Isopentenyl phosphate kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. (258 aa) | ||||
SEI71404.1 | Glycosidase. (673 aa) | ||||
SEI71565.1 | Demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase. (206 aa) | ||||
fumC | Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (469 aa) | ||||
ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa) | ||||
SEI76163.1 | Myo-inositol-1(or 4)-monophosphatase. (263 aa) | ||||
menE | O-succinylbenzoic acid--CoA ligase; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. (554 aa) | ||||
SEI76973.1 | Isopentenyl-diphosphate delta-isomerase. (188 aa) | ||||
SEI74822.1 | L-threonine synthase. (397 aa) | ||||
aroE | Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (267 aa) | ||||
SEI75171.1 | Aminodeoxychorismate synthase, subunit I. (524 aa) | ||||
SEI75189.1 | Anthranilate synthase component 2. (218 aa) | ||||
SEI75212.1 | Branched chain amino acid aminotransferase apoenzyme; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (303 aa) | ||||
SEI75450.1 | acetyl-CoA C-acetyltransferase. (388 aa) | ||||
trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa) | ||||
trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (215 aa) | ||||
trpE | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] (535 aa) | ||||
SEI76048.1 | Anthranilate synthase component 2. (217 aa) | ||||
hisI | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (122 aa) | ||||
SEI80462.1 | Phosphomannomutase / phosphoglucomutase; Belongs to the phosphohexose mutase family. (451 aa) | ||||
SEI80504.1 | Dihydrolipoamide dehydrogenase. (474 aa) | ||||
SEI80590.1 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). (525 aa) | ||||
SEI80608.1 | Pyruvate dehydrogenase E1 component beta subunit. (339 aa) | ||||
SEI80633.1 | Pyruvate dehydrogenase E1 component alpha subunit. (367 aa) | ||||
SEI78469.1 | Malate dehydrogenase (NAD); Belongs to the LDH/MDH superfamily. (304 aa) | ||||
SEI78948.1 | Prephenate dehydratase. (270 aa) | ||||
hisE | phosphoribosyl-ATP pyrophosphatase. (103 aa) | ||||
SEI78326.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) | ||||
SEI78345.1 | Phosphoserine phosphatase. (217 aa) | ||||
SEI79605.1 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. (280 aa) | ||||
SEI80005.1 | 6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. (299 aa) | ||||
SEI85460.1 | NAD+ dependent glucose-6-phosphate dehydrogenase. (267 aa) | ||||
SEI83199.1 | Protoporphyrin IX magnesium-chelatase. (722 aa) | ||||
SEI82867.1 | Aspartate aminotransferase. (375 aa) | ||||
SEI83386.1 | Pyruvate ferredoxin oxidoreductase beta subunit. (312 aa) | ||||
SEI83418.1 | Pyruvate ferredoxin oxidoreductase alpha subunit. (632 aa) | ||||
aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (384 aa) | ||||
menA | 1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (311 aa) | ||||
SEI83814.1 | 3-isopropylmalate dehydrogenase. (327 aa) | ||||
SEI83842.1 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit. (210 aa) | ||||
leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa) | ||||
ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (335 aa) | ||||
SEI83954.1 | Acetolactate synthase, small subunit. (233 aa) | ||||
SEI83973.1 | Acetolactate synthase, large subunit. (590 aa) | ||||
SEI83997.1 | 2-isopropylmalate synthase. (345 aa) | ||||
SEI84232.1 | Cytochrome c oxidase assembly protein subunit 15. (288 aa) | ||||
gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (504 aa) | ||||
SEI85064.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa) | ||||
SEI86838.1 | Glucose-1-phosphate thymidylyltransferase. (248 aa) | ||||
SEI86909.1 | Aldehyde dehydrogenase (acceptor). (508 aa) | ||||
proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (247 aa) | ||||
proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (284 aa) | ||||
proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (451 aa) | ||||
aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (443 aa) | ||||
hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (217 aa) | ||||
SEI88043.1 | Glucokinase. (322 aa) | ||||
SEI88136.1 | Aminomethyltransferase. (369 aa) | ||||
SEI88253.1 | Riboflavin synthase alpha chain. (205 aa) | ||||
trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (255 aa) | ||||
trpB | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (412 aa) | ||||
trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (285 aa) | ||||
aroA-2 | 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase; Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7- dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids. (264 aa) | ||||
aroB | 3-dehydroquinate synthase II; Catalyzes the oxidative deamination and cyclization of 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis; Belongs to the archaeal-type DHQ synthase family. (387 aa) | ||||
SEI91003.1 | Adenylosuccinate lyase. (471 aa) | ||||
SEI91024.1 | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. (571 aa) | ||||
sucD | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) | ||||
sucC | succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (381 aa) | ||||
SEI92404.1 | Asparagine synthase (glutamine-hydrolysing). (389 aa) | ||||
purL | Phosphoribosylformylglycinamidine synthase subunit II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (729 aa) | ||||
SEI92609.1 | Phosphoglycolate phosphatase. (175 aa) | ||||
panB | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (269 aa) | ||||
gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (573 aa) | ||||
eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa) | ||||
SEI94513.1 | Glycosidase. (728 aa) | ||||
SEI95403.1 | Aspartate/methionine/tyrosine aminotransferase. (367 aa) | ||||
SEI95559.1 | acetyl-CoA/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein. (600 aa) | ||||
SEI95644.1 | Hypothetical protein. (112 aa) | ||||
SEI95657.1 | propionyl-CoA carboxylase carboxyltransferase subunit. (516 aa) | ||||
SEI96826.1 | Isocitrate dehydrogenase (NADP). (420 aa) | ||||
SEI96883.1 | Undecaprenyl diphosphate synthase. (249 aa) | ||||
SEI97214.1 | 3-oxoacyl-[acyl-carrier-protein] reductase. (247 aa) | ||||
SEI97297.1 | Succinate dehydrogenase subunit A. (623 aa) | ||||
SEI97491.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (585 aa) | ||||
SEI96654.1 | hydroxymethylglutaryl-CoA synthase. (446 aa) | ||||
pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (430 aa) | ||||
pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (406 aa) | ||||
SEI97926.1 | Glyceraldehyde-3-phosphate dehydrogenase (NAD+); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (350 aa) | ||||
SEI98068.1 | Citrate synthase. (378 aa) | ||||
SEI98107.1 | Acetylornithine deacetylase. (365 aa) | ||||
SEI98966.1 | Trehalose 6-phosphate phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose. (286 aa) | ||||
SEI99057.1 | Porphobilinogen synthase; Belongs to the ALAD family. (328 aa) | ||||
SEI99401.1 | Aspartate-semialdehyde dehydrogenase. (346 aa) | ||||
SEI99669.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (775 aa) | ||||
SEI99762.1 | Glucose 1-dehydrogenase/3-oxoacyl-[acyl-carrier protein] reductase. (266 aa) | ||||
SEI99887.1 | Citrate synthase. (378 aa) | ||||
SEI99901.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa) | ||||
gap | Glyceraldehyde 3-phosphate dehydrogenase (NAD(P)+). (355 aa) | ||||
SEI98949.1 | Trehalose 6-phosphate synthase. (517 aa) | ||||
surE | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (278 aa) | ||||
SEJ02044.1 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (422 aa) | ||||
SEJ02081.1 | Glycerol 3-phosphate dehydrogenase (quinone) subunit C. (434 aa) | ||||
SEJ02103.1 | Glycerol 3-phosphate dehydrogenase (quinone) subunit B. (432 aa) | ||||
SEJ02124.1 | Glycerol 3-phosphate dehydrogenase (quinone) subunit A; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (580 aa) | ||||
SEJ00879.1 | Probable phosphoglycerate mutase. (209 aa) | ||||
SEJ05474.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (390 aa) | ||||
SEJ05608.1 | Glycerol 3-phosphate dehydrogenase (quinone) subunit B. (457 aa) | ||||
SEJ05622.1 | Glycerol 3-phosphate dehydrogenase (quinone) subunit A; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (564 aa) | ||||
katG | Catalase-peroxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (714 aa) | ||||
SEJ08520.1 | Dihydrolipoamide dehydrogenase. (471 aa) | ||||
SEJ08751.1 | Succinate dehydrogenase subunit C. (141 aa) | ||||
SEJ08769.1 | Succinate dehydrogenase subunit D. (123 aa) | ||||
SEJ08792.1 | Succinate dehydrogenase subunit B. (300 aa) | ||||
SEJ08805.1 | Succinate dehydrogenase subunit A. (614 aa) | ||||
SEJ09033.1 | acetyl-CoA synthetase. (669 aa) | ||||
SEJ09181.1 | Arginase; Belongs to the arginase family. (302 aa) | ||||
SEJ13966.1 | Phosphatidylserine decarboxylase. (200 aa) | ||||
hisF | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (270 aa) | ||||
SEJ14181.1 | Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase. (224 aa) | ||||
hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (460 aa) | ||||
SEJ14255.1 | Phosphoglycolate phosphatase. (225 aa) | ||||
SEJ13639.1 | Fructose-bisphosphate aldolase. (262 aa) | ||||
aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (233 aa) | ||||
ribL | FAD synthetase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (145 aa) | ||||
fbp-3 | D-fructose 1,6-bisphosphatase; Belongs to the FBPase class 1 family. (292 aa) | ||||
SEJ15246.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) | ||||
SEJ15266.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit beta. (287 aa) | ||||
SEJ15285.1 | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (586 aa) | ||||
menB | 1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily. (304 aa) | ||||
menD | 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (584 aa) | ||||
gap-2 | Glyceraldehyde 3-phosphate dehydrogenase (NAD(P)+). (342 aa) | ||||
SEJ18993.1 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (754 aa) | ||||
SEJ19897.1 | Aldehyde dehydrogenase (NAD+). (503 aa) | ||||
SEJ19691.1 | L-proline dehydrogenase. (294 aa) | ||||
thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (291 aa) | ||||
SEJ24005.1 | Lipid kinase, YegS/Rv2252/BmrU family. (306 aa) | ||||
SEJ24153.1 | Phytoene synthase. (345 aa) | ||||
SEJ23807.1 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (421 aa) | ||||
SEJ24923.1 | 3-ketoacyl-CoA thiolase. (377 aa) | ||||
SEJ24509.1 | Glucose-1-phosphate thymidylyltransferase. (320 aa) | ||||
SEJ24579.1 | Bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase. (403 aa) | ||||
SEJ26618.1 | Homoserine dehydrogenase. (319 aa) | ||||
SEJ28090.1 | L-threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (463 aa) | ||||
SEJ27995.1 | Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (225 aa) | ||||
ilvD | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (581 aa) | ||||
guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (496 aa) | ||||
SEJ30545.1 | Isochorismate synthase. (480 aa) | ||||
SEJ30846.1 | Glucose-1-phosphate thymidylyltransferase. (406 aa) | ||||
SEJ31466.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa) | ||||
SEJ31861.1 | Glucose-1-phosphate thymidylyltransferase. (241 aa) | ||||
SEJ32856.1 | Acetyl-coenzyme A synthetase. (663 aa) | ||||
dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (307 aa) | ||||
dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (255 aa) | ||||
dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine. (296 aa) | ||||
lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (411 aa) | ||||
SEJ35741.1 | Phosphatidylserine decarboxylase. (204 aa) | ||||
surE-2 | 5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (270 aa) | ||||
SEJ38204.1 | Methyltransferase domain-containing protein. (226 aa) |