(5 nodes) Mur ligase middle domain, and Tetrahydrofolate biosynthetic process network (Torulaspora delbrueckii)

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Your Input:
	TDEL0A02110	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (424 aa)
	TDEL0A06030	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (204 aa)
	TDEL0A06150	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (491 aa)
	TDEL0B02450	Thymidylat_synt domain-containing protein. (308 aa)
	TDEL0C05970	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family. (796 aa)

Your Current Organism:

Torulaspora delbrueckii

NCBI taxonomy Id: 1076872
Other names: T. delbrueckii CBS 1146, Torulaspora delbrueckii CBS 1146

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TDEL0A02110	TDEL0A06030	G8ZLP9	G8ZMU1	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.972
TDEL0A02110	TDEL0A06150	G8ZLP9	G8ZMV3	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.916
TDEL0A02110	TDEL0B02450	G8ZLP9	G8ZP30	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	Thymidylat_synt domain-containing protein.	0.937
TDEL0A02110	TDEL0C05970	G8ZLP9	G8ZSJ4	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	0.989
TDEL0A06030	TDEL0A02110	G8ZMU1	G8ZLP9	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.972
TDEL0A06030	TDEL0A06150	G8ZMU1	G8ZMV3	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.977
TDEL0A06030	TDEL0B02450	G8ZMU1	G8ZP30	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Thymidylat_synt domain-containing protein.	0.999
TDEL0A06030	TDEL0C05970	G8ZMU1	G8ZSJ4	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	0.678
TDEL0A06150	TDEL0A02110	G8ZMV3	G8ZLP9	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.916
TDEL0A06150	TDEL0A06030	G8ZMV3	G8ZMU1	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.977
TDEL0A06150	TDEL0B02450	G8ZMV3	G8ZP30	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Thymidylat_synt domain-containing protein.	0.944
TDEL0A06150	TDEL0C05970	G8ZMV3	G8ZSJ4	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	0.981
TDEL0B02450	TDEL0A02110	G8ZP30	G8ZLP9	Thymidylat_synt domain-containing protein.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.937
TDEL0B02450	TDEL0A06030	G8ZP30	G8ZMU1	Thymidylat_synt domain-containing protein.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.999
TDEL0B02450	TDEL0A06150	G8ZP30	G8ZMV3	Thymidylat_synt domain-containing protein.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.944
TDEL0B02450	TDEL0C05970	G8ZP30	G8ZSJ4	Thymidylat_synt domain-containing protein.	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	0.649
TDEL0C05970	TDEL0A02110	G8ZSJ4	G8ZLP9	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family.	0.989
TDEL0C05970	TDEL0A06030	G8ZSJ4	G8ZMU1	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.678
TDEL0C05970	TDEL0A06150	G8ZSJ4	G8ZMV3	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.	0.981
TDEL0C05970	TDEL0B02450	G8ZSJ4	G8ZP30	Folic acid synthesis protein fol1; Catalyzes three sequential steps of tetrahydrofolate biosynthesis; In the C-terminal section; belongs to the DHPS family. In the central section; belongs to the HPPK family.	Thymidylat_synt domain-containing protein.	0.649