STRINGSTRING
BVIR_235 BVIR_235 mcl2_2 mcl2_2 sucB sucB bclA bclA metZ metZ mtnP mtnP sufE sufE BVIR_2277 BVIR_2277 BVIR_2276 BVIR_2276 mdeA_3 mdeA_3 thiL thiL cysE_2 cysE_2 metE_1 metE_1 BVIR_2111 BVIR_2111 sufS_2 sufS_2 fccB fccB BVIR_2064 BVIR_2064 BVIR_2063 BVIR_2063 sir_1 sir_1 cysH cysH cysD_1 cysD_1 cysNC_1 cysNC_1 mccA mccA BVIR_196 BVIR_196 dxs_1 dxs_1 thiG_1 thiG_1 thiE_2 thiE_2 bfmBAB bfmBAB pdhC pdhC lipA_1 lipA_1 scpC scpC bioK bioK mcl1 mcl1 BVIR_1778 BVIR_1778 BVIR_1764 BVIR_1764 hom hom yfcG_2 yfcG_2 bioB bioB BVIR_162 BVIR_162 mdeA_2 mdeA_2 metX metX erpA erpA sseA sseA metC_2 metC_2 yfcF_1 yfcF_1 acsA_4 acsA_4 BVIR_1356 BVIR_1356 cysE_1 cysE_1 mcl2_1 mcl2_1 iscA_1 iscA_1 BVIR_1145 BVIR_1145 sufS_1 sufS_1 sufD sufD sufC sufC sufB sufB tesB_1 tesB_1 accC accC BVIR_1073 BVIR_1073 BVIR_2715 BVIR_2715 gshA gshA accA_1 accA_1 bioA bioA BVIR_2939 BVIR_2939 gshB_1 gshB_1 folD folD cysD_2 cysD_2 cysNC_2 cysNC_2 acsA_3 acsA_3 thiC thiC BVIR_3079 BVIR_3079 BVIR_3093 BVIR_3093 BVIR_3177 BVIR_3177 cysK1 cysK1 accD accD mtnA mtnA fucA fucA BVIR_3268 BVIR_3268 asd2 asd2 BVIR_331 BVIR_331 metC_1 metC_1 cbs_1 cbs_1 acsA_1 acsA_1 metF metF metH metH cysQ cysQ mdeA_1 mdeA_1 hemA_1 hemA_1 nfuA nfuA metK metK BVIR_762 BVIR_762 gor gor minD_1 minD_1 yfcG_1 yfcG_1 acs acs thiM thiM thiE_1 thiE_1 thiD thiD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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BVIR_235Thiamine-phosphate synthase. (203 aa)
mcl2_2(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family. (296 aa)
sucBDihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (410 aa)
bclAAcetyl-coenzyme A synthetase. (540 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (398 aa)
mtnPS-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (292 aa)
sufECysteine desulfuration protein SufE. (161 aa)
BVIR_2277NifU-like domain protein. (111 aa)
BVIR_2276Iron-sulfur cluster insertion protein ErpA; Belongs to the HesB/IscA family. (106 aa)
mdeA_3Methionine gamma-lyase. (429 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (694 aa)
cysE_2Serine acetyltransferase. (285 aa)
metE_15-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (780 aa)
BVIR_2111Putative acyl-CoA thioester hydrolase. (263 aa)
sufS_2Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (626 aa)
fccBSulfide dehydrogenase [flavocytochrome c] flavoprotein chain precursor. (430 aa)
BVIR_2064Sulfur oxidation protein SoxY. (156 aa)
BVIR_2063Sulfur oxidation protein SoxZ. (110 aa)
sir_1Sulfite reductase [ferredoxin]. (553 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (235 aa)
cysD_1Sulfate adenylyltransferase subunit 2. (323 aa)
cysNC_1Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (642 aa)
mccAO-acetylserine dependent cystathionine beta-synthase. (343 aa)
BVIR_196Glyoxalase-like domain protein. (140 aa)
dxs_11-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
thiG_1Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa)
thiE_2Thiamine-phosphate synthase. (212 aa)
bfmBAB2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (470 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa)
lipA_1Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (316 aa)
scpCSuccinyl-CoA:coenzyme A transferase. (505 aa)
bioKL-Lysine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
mcl1Malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (347 aa)
BVIR_1778NifU-like protein. (152 aa)
BVIR_1764Glutathionyl-hydroquinone reductase YqjG. (337 aa)
homHomoserine dehydrogenase. (436 aa)
yfcG_2Disulfide-bond oxidoreductase YfcG; Belongs to the GST superfamily. (215 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. (330 aa)
BVIR_162ChaC-like protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (200 aa)
mdeA_2Methionine gamma-lyase. (431 aa)
metXHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (395 aa)
erpAIron-sulfur cluster insertion protein ErpA; Belongs to the HesB/IscA family. (108 aa)
sseA3-mercaptopyruvate sulfurtransferase. (282 aa)
metC_2Cystathionine beta-lyase MetC. (403 aa)
yfcF_1Glutathione S-transferase YfcF. (224 aa)
acsA_4Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
BVIR_1356Hypothetical protein. (283 aa)
cysE_1Serine acetyltransferase. (284 aa)
mcl2_1(3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family. (299 aa)
iscA_1Iron-binding protein IscA; Belongs to the HesB/IscA family. (124 aa)
BVIR_1145Hypothetical protein. (135 aa)
sufS_1Cysteine desulfurase; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
sufDFeS cluster assembly protein SufD. (442 aa)
sufCPutative ATP-dependent transporter SufC. (248 aa)
sufBFeS cluster assembly protein SufB. (494 aa)
tesB_1Acyl-CoA thioesterase 2. (288 aa)
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
BVIR_1073Hypothetical protein. (234 aa)
BVIR_2715Omega-amino acid--pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (444 aa)
gshAGlutamate--cysteine ligase GshA; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (456 aa)
accA_1Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (341 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa)
BVIR_293927 kDa antigen Cfp30B. (124 aa)
gshB_1Glutathione synthetase; Belongs to the prokaryotic GSH synthase family. (313 aa)
folDBifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
cysD_2Sulfate adenylyltransferase subunit 2. (343 aa)
cysNC_2Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (639 aa)
acsA_3Acetyl-coenzyme A synthetase. (654 aa)
thiCPhosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (612 aa)
BVIR_3079Hypothetical protein. (118 aa)
BVIR_3093CysZ-like protein. (240 aa)
BVIR_3177Hypothetical protein. (115 aa)
cysK1O-acetylserine sulfhydrylase. (326 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (317 aa)
mtnAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (369 aa)
fucAL-fuculose phosphate aldolase. (211 aa)
BVIR_3268Putative glutathione S-transferase. (237 aa)
asd2Aspartate-semialdehyde dehydrogenase 2; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
BVIR_3312'-N-acetylparomamine deacetylase. (217 aa)
metC_1Cystathionine beta-lyase. (395 aa)
cbs_1Putative cystathionine beta-synthase. (461 aa)
acsA_1Acetyl-coenzyme A synthetase. (566 aa)
metF5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (302 aa)
metHMethionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1244 aa)
cysQ3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (273 aa)
mdeA_1Methionine gamma-lyase. (436 aa)
hemA_15-aminolevulinate synthase. (409 aa)
nfuAFe/S biogenesis protein NfuA. (185 aa)
metKS-adenosylmethionine synthase; Belongs to the AdoMet synthase family. (397 aa)
BVIR_762Putative GST-like protein YibF. (200 aa)
gorGlutathione amide reductase; Maintains high levels of reduced glutathione. (453 aa)
minD_1Septum site-determining protein MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (371 aa)
yfcG_1Disulfide-bond oxidoreductase YfcG; Belongs to the GST superfamily. (205 aa)
acsAcetyl-coenzyme A synthetase. (646 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa)
thiE_1Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa)
thiDHydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (265 aa)
Your Current Organism:
Blastochloris viridis
NCBI taxonomy Id: 1079
Other names: ATCC 19567, B. viridis, CCUG 30818, CCUG 7830, DSM 133, LMG 4321, LMG:4321, NBRC 102659, Rhodopseudomonas viridis, strain G. Drews F
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