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| | BVIR_1437 | ATP-dependent RecD-like DNA helicase. (1991 aa) |
| | ppaX | Pyrophosphatase PpaX. (223 aa) |
| | acsA_4 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (195 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (331 aa) |
| | nadC_1 | Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (281 aa) |
| | yfaY | Putative competence-damage inducible protein. (249 aa) |
| | phnN | Ribose 1,5-bisphosphate phosphokinase PhnN. (199 aa) |
| | BVIR_1271 | Hypothetical protein. (232 aa) |
| | ppnK_1 | Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (260 aa) |
| | mcl2_1 | (3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family. (299 aa) |
| | BVIR_1197 | PglZ domain protein. (664 aa) |
| | anmK | Anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (384 aa) |
| | BVIR_1122 | Polyphosphate kinase 2 (PPK2). (295 aa) |
| | tesB_1 | Acyl-CoA thioesterase 2. (288 aa) |
| | accC | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (745 aa) |
| | pgsA2 | Putative CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyl-transferase 2. (176 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase. (360 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (213 aa) |
| | ndk_1 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | BVIR_1066 | Putative hydroxypyruvate reductase. (419 aa) |
| | acpXL | Acyl carrier protein AcpXL. (93 aa) |
| | fabZ_1 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ. (165 aa) |
| | nnr | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to al [...] (510 aa) |
| | purB | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. (255 aa) |
| | dagK | Diacylglycerol kinase. (330 aa) |
| | yexA | Phosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (79 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (233 aa) |
| | purL_1 | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (742 aa) |
| | mcp4_6 | Methyl-accepting chemotaxis protein 4. (149 aa) |
| | BVIR_1012 | Blue-light-activated protein. (840 aa) |
| | ubiB_3 | Putative protein kinase UbiB. (452 aa) |
| | coaBC | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (407 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa) |
| | divL | Sensor protein DivL. (828 aa) |
| | BVIR_3197 | Hypothetical protein. (203 aa) |
| | pdxY_1 | Pyridoxamine kinase; Belongs to the pyridoxine kinase family. (287 aa) |
| | BVIR_3221 | Deoxycytidine triphosphate deaminase. (374 aa) |
| | phoR_2 | Alkaline phosphatase synthesis sensor protein PhoR. (442 aa) |
| | accD | Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (317 aa) |
| | regB | Sensor histidine kinase RegB. (443 aa) |
| | coaA | Pantothenate kinase. (320 aa) |
| | BVIR_327 | Kanosamine kinase. (302 aa) |
| | coaE | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (198 aa) |
| | maf | Maf-like protein YceF; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (198 aa) |
| | yqfL | Putative pyruvate, phosphate dikinase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (283 aa) |
| | BVIR_3307 | DNA-binding transcriptional dual regulator Crp. (155 aa) |
| | ppa_1 | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (180 aa) |
| | purH | Bifunctional purine biosynthesis protein PurH. (529 aa) |
| | gph_1 | Phosphoglycolate phosphatase. (231 aa) |
| | thlA_1 | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa) |
| | acsA_1 | Acetyl-coenzyme A synthetase. (566 aa) |
| | lpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. (279 aa) |
| | purU_1 | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (300 aa) |
| | yfkJ | Low molecular weight protein-tyrosine-phosphatase YfkJ. (170 aa) |
| | BVIR_433 | Fructosamine kinase. (268 aa) |
| | ydjH | 2-dehydro-3-deoxygluconokinase. (309 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase CysQ; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (273 aa) |
| | BVIR_472 | Hypothetical protein. (218 aa) |
| | cheA_1 | Chemotaxis protein CheA. (897 aa) |
| | atpH | ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (186 aa) |
| | yscN | Putative ATP synthase YscN. (451 aa) |
| | fixL_1 | Sensor protein FixL. (681 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (509 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa) |
| | cheA_2 | Chemotaxis protein CheA. (696 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (479 aa) |
| | BVIR_521 | Polyphosphate kinase 2 (PPK2). (314 aa) |
| | atpC | ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. (144 aa) |
| | yqaB_1 | Fructose-1-phosphate phosphatase YqaB. (241 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (312 aa) |
| | fixL_2 | Sensor protein FixL. (385 aa) |
| | rppH | RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (175 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. (423 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (268 aa) |
| | rpe_1 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | tktA | Transketolase 1; Belongs to the transketolase family. (672 aa) |
| | prkA | Phosphoribulokinase 1. (291 aa) |
| | ispH_1 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (337 aa) |
| | nadD | Nicotinate-nucleotide adenylyltransferase. (209 aa) |
| | pleC_1 | Non-motile and phage-resistance protein. (1184 aa) |
| | proB_1 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (405 aa) |
| | purF_1 | Amidophosphoribosyltransferase precursor; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (489 aa) |
| | BVIR_67 | tRNA-specific adenosine deaminase. (541 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (221 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (336 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (230 aa) |
| | pyrC_1 | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (356 aa) |
| | BVIR_719 | Phosphotransferase enzyme family protein. (513 aa) |
| | mog | Molybdopterin adenylyltransferase. (179 aa) |
| | BVIR_733 | Blue-light-activated histidine kinase 1. (650 aa) |
| | yhdE | Maf-like protein YhdE; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (207 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (322 aa) |
| | suhB_1 | Inositol-1-monophosphatase. (274 aa) |
| | gmr_5 | Cyclic di-GMP phosphodiesterase Gmr. (963 aa) |
| | BVIR_77 | Hypothetical protein; Belongs to the UPF0301 (AlgH) family. (204 aa) |
| | moaA_1 | Cyclic pyranopterin monophosphate synthase; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (349 aa) |
| | nadE_1 | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (556 aa) |
| | dgkA | Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid. (119 aa) |
| | rpiA_1 | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (238 aa) |
| | rsh | GTP pyrophosphokinase rsh; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (739 aa) |
| | BVIR_819 | Blue-light-activated histidine kinase. (810 aa) |
| | pleC_2 | Non-motile and phage-resistance protein. (515 aa) |
| | acs | Acetyl-coenzyme A synthetase. (646 aa) |
| | carB_1 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1151 aa) |
| | carA_1 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (395 aa) |
| | nadE_2 | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (339 aa) |
| | gph_3 | Phosphoglycolate phosphatase. (220 aa) |
| | tal | Transaldolase. (257 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (267 aa) |
| | thiE_1 | Thiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (218 aa) |
| | thiD | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. (265 aa) |
| | BVIR_949 | UDP-2,3-diacylglucosamine hydrolase. (270 aa) |
| | BVIR_963 | Hypothetical protein. (126 aa) |
| | moeZ_3 | Putative adenylyltransferase/sulfurtransferase MoeZ. (269 aa) |
| | gmr_4 | Cyclic di-GMP phosphodiesterase Gmr. (1115 aa) |
| | pyrD | Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (356 aa) |
| | purA_1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | pfkB | Putative phosphofructokinase PfkB; Belongs to the carbohydrate kinase PfkB family. (315 aa) |
| | thyA_1 | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa) |
| | BVIR_3051 | Stringent starvation protein B. (192 aa) |
| | thiC | Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (612 aa) |
| | acsA_3 | Acetyl-coenzyme A synthetase. (654 aa) |
| | cysNC_2 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (639 aa) |
| | pyk | Pyruvate kinase; Belongs to the pyruvate kinase family. (477 aa) |
| | nadC_2 | Putative nicotinate-nucleotide pyrophosphorylase [carboxylating]; Belongs to the NadC/ModD family. (288 aa) |
| | nadB | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (540 aa) |
| | ptsI | Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family. (755 aa) |
| | nadA | Quinolinate synthase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (362 aa) |
| | folD | Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | lysC_1 | Aspartokinase; Belongs to the aspartokinase family. (417 aa) |
| | glnL_3 | Nitrogen regulation protein NR(II). (512 aa) |
| | nudC_1 | NADH pyrophosphatase; Belongs to the Nudix hydrolase family. (323 aa) |
| | barA | Signal transduction histidine-protein kinase BarA. (653 aa) |
| | BVIR_2944 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (216 aa) |
| | BVIR_2939 | 27 kDa antigen Cfp30B. (124 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (207 aa) |
| | ubiB_1 | Putative protein kinase UbiB. (440 aa) |
| | manX | PTS system mannose-specific EIIAB component. (133 aa) |
| | hprK | HPr kinase/phosphorylase. (181 aa) |
| | phoR_1 | Alkaline phosphatase synthesis sensor protein PhoR. (601 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (324 aa) |
| | accA_1 | Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (341 aa) |
| | pdhS | Cell-division control histidine kinase PdhS. (1072 aa) |
| | cmk | Cytidylate kinase. (214 aa) |
| | aroK_1 | Shikimate kinase 1; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (204 aa) |
| | BVIR_2797 | Hypothetical protein. (170 aa) |
| | pgi_1 | Glucose-6-phosphate isomerase. (439 aa) |
| | BVIR_2746 | Ribokinase. (305 aa) |
| | ispH_2 | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (335 aa) |
| | thrB | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. (321 aa) |
| | purE | N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | purK | N5-carboxyaminoimidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (371 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Belongs to the ribF family. (331 aa) |
| | atpF | ATP synthase subunit b precursor; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (161 aa) |
| | atpX | ATP synthase subunit b 2; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (181 aa) |
| | atpE | ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (75 aa) |
| | atpB | ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (249 aa) |
| | mcl2_2 | (3S)-malyl-CoA thioesterase; Belongs to the HpcH/HpaI aldolase family. (296 aa) |
| | BVIR_2661 | Beta-lactamase hydrolase-like protein. (225 aa) |
| | BVIR_2660 | Blue-light-activated histidine kinase. (629 aa) |
| | sucA | 2-oxoglutarate dehydrogenase E1 component. (988 aa) |
| | sucB | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (410 aa) |
| | sulD | Bifunctional folate synthesis protein. (165 aa) |
| | BVIR_2634 | Putative GTPase. (336 aa) |
| | idi | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (185 aa) |
| | hisN | Histidinol-phosphatase. (260 aa) |
| | bclA | Acetyl-coenzyme A synthetase. (540 aa) |
| | BVIR_2493 | Putative Nudix hydrolase NudL. (217 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | pgsA | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (205 aa) |
| | moaD | Molybdopterin synthase sulfur carrier subunit. (89 aa) |
| | moaE | Molybdopterin synthase catalytic subunit. (157 aa) |
| | envZ_1 | Osmolarity sensor protein EnvZ. (456 aa) |
| | fbpC2 | Fe(3+) ions import ATP-binding protein FbpC 2; Belongs to the ABC transporter superfamily. (346 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (238 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; Belongs to the CDS family. (278 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (404 aa) |
| | lpxD | UDP-3-O-acylglucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (358 aa) |
| | fabZ_2 | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (154 aa) |
| | lpxA | Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (266 aa) |
| | BVIR_2425 | Hypothetical protein. (289 aa) |
| | lpxB | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (392 aa) |
| | gmr_3 | Cyclic di-GMP phosphodiesterase Gmr. (892 aa) |
| | BVIR_2395 | (S)-2-haloacid dehalogenase 4A. (220 aa) |
| | BVIR_2384 | Hypothetical protein. (454 aa) |
| | aphA | Aminoglycoside 3'-phosphotransferase. (258 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (397 aa) |
| | BVIR_235 | Thiamine-phosphate synthase. (203 aa) |
| | phoQ_2 | Sensor protein PhoQ. (472 aa) |
| | cusS | Sensor kinase CusS. (468 aa) |
| | suhB_2 | Inositol-1-monophosphatase. (262 aa) |
| | pleC_3 | Non-motile and phage-resistance protein. (759 aa) |
| | guaA_2 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. (521 aa) |
| | gmr_2 | Cyclic di-GMP phosphodiesterase Gmr. (869 aa) |
| | cofC | 2-phospho-L-lactate guanylyltransferase. (227 aa) |
| | BVIR_2234 | Nicotine blue oxidoreductase. (281 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (498 aa) |
| | psd | Phosphatidylserine decarboxylase proenzyme; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (246 aa) |
| | BVIR_2197 | CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (305 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (694 aa) |
| | plsX | Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (355 aa) |
| | fadA | 3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (378 aa) |
| | hldE_1 | Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (487 aa) |
| | dctB | C4-dicarboxylate transport sensor protein DctB. (614 aa) |
| | gsk | 2-dehydro-3-deoxygluconokinase. (332 aa) |
| | BVIR_2111 | Putative acyl-CoA thioester hydrolase. (263 aa) |
| | cysNC_1 | Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (642 aa) |
| | BVIR_2005 | Hypothetical protein; Belongs to the UPF0434 family. (76 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (892 aa) |
| | BVIR_1998 | Putative GTPase. (327 aa) |
| | cobC | Putative phosphoserine phosphatase 2. (180 aa) |
| | cobU_2 | Bifunctional adenosylcobalamin biosynthesis protein CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (172 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (289 aa) |
| | pdxH_1 | Pyridoxine/pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (206 aa) |
| | BVIR_1961 | Glucosyl-3-phosphoglycerate phosphatase. (209 aa) |
| | BVIR_196 | Glyoxalase-like domain protein. (140 aa) |
| | dxs_1 | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa) |
| | thiG_1 | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (255 aa) |
| | thiE_2 | Thiamine-phosphate synthase. (212 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa) |
| | bfmBAB | 2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (470 aa) |
| | pdhC | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa) |
| | ygaD | Nicotinamide-nucleotide amidohydrolase PncC; Belongs to the CinA family. (165 aa) |
| | ispDF | Bifunctional enzyme IspD/IspF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (398 aa) |
| | glnL_2 | Nitrogen regulation protein NR(II). (378 aa) |
| | glnL_1 | Nitrogen regulation protein NR(II). (756 aa) |
| | BVIR_1909 | Hypothetical protein. (409 aa) |
| | scpC | Succinyl-CoA:coenzyme A transferase. (505 aa) |
| | BVIR_1904 | Putative metallophosphoesterase. (313 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (435 aa) |
| | kdpD | Sensor protein KdpD. (895 aa) |
| | mcl1 | Malyl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (347 aa) |
| | pcs_1 | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (251 aa) |
| | purT_1 | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (393 aa) |
| | phoQ_1 | Sensor protein PhoQ. (456 aa) |
| | folE_1 | GTP cyclohydrolase 1. (211 aa) |
| | BVIR_1766 | Putative acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa) |
| | BVIR_1696 | Blue-light-activated histidine kinase. (585 aa) |
| | hpt_1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (192 aa) |
| | BVIR_1683 | Hypothetical protein. (251 aa) |
| | thlA_2 | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa) |
| | BVIR_1662 | Blue-light-activated histidine kinase. (1060 aa) |
| | plsY | Putative glycerol-3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (227 aa) |
| | pyrC_2 | Dihydroorotase. (439 aa) |
| | pyrB_1 | Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa) |
| | mazG | Nucleoside triphosphate pyrophosphohydrolase. (285 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (227 aa) |
| | plsC | 1-acyl-sn-glycerol-3-phosphate acyltransferase. (240 aa) |
| | pyrG_1 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (542 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (266 aa) |
| | yfkN | Trifunctional nucleotide phosphoesterase protein YfkN precursor; Belongs to the 5'-nucleotidase family. (500 aa) |
| | BVIR_160 | Hypothetical protein. (193 aa) |
| | moaC | Cyclic pyranopterin monophosphate synthase accessory protein; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (167 aa) |
| | moeA | Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (401 aa) |
| | acsA_2 | Acetyl-coenzyme A synthetase. (356 aa) |
| | surE | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (253 aa) |
| | dgt | Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (392 aa) |
| | coaD | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | glmU | Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (453 aa) |
| | phbA | Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa) |
| | hit_1 | HIT-like protein. (141 aa) |
| | cph2_5 | Phytochrome-like protein cph2. (566 aa) |
