node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BVIR_1017 | aarA | BVIR_1017 | BVIR_2423 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Citrate synthase; Belongs to the citrate synthase family. | 0.837 |
BVIR_1017 | aceB | BVIR_1017 | BVIR_717 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Malate synthase A; Belongs to the malate synthase family. | 0.664 |
BVIR_1017 | fumC | BVIR_1017 | BVIR_2912 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.581 |
BVIR_1017 | mdh | BVIR_1017 | BVIR_2648 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.942 |
BVIR_1017 | sdhA | BVIR_1017 | BVIR_2656 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.531 |
BVIR_1017 | sucC | BVIR_1017 | BVIR_2647 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.921 |
BVIR_1017 | sucD_1 | BVIR_1017 | BVIR_2646 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.833 |
aarA | BVIR_1017 | BVIR_2423 | BVIR_1017 | Citrate synthase; Belongs to the citrate synthase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.837 |
aarA | aceB | BVIR_2423 | BVIR_717 | Citrate synthase; Belongs to the citrate synthase family. | Malate synthase A; Belongs to the malate synthase family. | 0.956 |
aarA | fumC | BVIR_2423 | BVIR_2912 | Citrate synthase; Belongs to the citrate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.902 |
aarA | mdh | BVIR_2423 | BVIR_2648 | Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.981 |
aarA | sdhA | BVIR_2423 | BVIR_2656 | Citrate synthase; Belongs to the citrate synthase family. | Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.621 |
aarA | sucB | BVIR_2423 | BVIR_2644 | Citrate synthase; Belongs to the citrate synthase family. | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.640 |
aarA | sucC | BVIR_2423 | BVIR_2647 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.898 |
aarA | sucD_1 | BVIR_2423 | BVIR_2646 | Citrate synthase; Belongs to the citrate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.634 |
aceB | BVIR_1017 | BVIR_717 | BVIR_1017 | Malate synthase A; Belongs to the malate synthase family. | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.664 |
aceB | aarA | BVIR_717 | BVIR_2423 | Malate synthase A; Belongs to the malate synthase family. | Citrate synthase; Belongs to the citrate synthase family. | 0.956 |
aceB | fumC | BVIR_717 | BVIR_2912 | Malate synthase A; Belongs to the malate synthase family. | Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.937 |
aceB | mdh | BVIR_717 | BVIR_2648 | Malate synthase A; Belongs to the malate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.944 |
aceB | sucC | BVIR_717 | BVIR_2647 | Malate synthase A; Belongs to the malate synthase family. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.831 |