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accC accC accB accB acoD_1 acoD_1 acsA_4 acsA_4 acyP_1 acyP_1 phbA phbA gloB gloB cfiB cfiB BVIR_1583 BVIR_1583 thlA_2 thlA_2 gloA gloA BVIR_1766 BVIR_1766 scpC scpC lpd lpd pdhC pdhC bfmBAB bfmBAB acoA acoA ldhA ldhA ppdK ppdK leuA_2 leuA_2 porB porB gcdB_2 gcdB_2 gcdB_3 gcdB_3 bclA bclA lpd3 lpd3 mdh mdh BVIR_2729 BVIR_2729 tme tme accA_1 accA_1 fumC fumC leuA_3 leuA_3 frdA frdA frdB frdB frdC frdC frdD frdD pyk pyk pckG pckG BVIR_3140 BVIR_3140 accD accD thlA_1 thlA_1 acsA_1 acsA_1 BVIR_455 BVIR_455 porA porA aceB aceB gcdB_1 gcdB_1 leuA_1 leuA_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
accCBiotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa)
accBBiotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
acoD_1Acetaldehyde dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (506 aa)
acsA_4Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (650 aa)
acyP_1Acylphosphatase. (97 aa)
phbAAcetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (253 aa)
cfiB2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1161 aa)
BVIR_1583Putative FAD-linked oxidoreductase. (477 aa)
thlA_2Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (417 aa)
gloALactoylglutathione lyase. (152 aa)
BVIR_1766Putative acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
scpCSuccinyl-CoA:coenzyme A transferase. (505 aa)
lpdDihydrolipoyl dehydrogenase. (477 aa)
pdhCDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (452 aa)
bfmBAB2-oxoisovalerate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (470 aa)
acoAAcetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (361 aa)
ldhAD-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
ppdKPyruvate, phosphate dikinase; Belongs to the PEP-utilizing enzyme family. (892 aa)
leuA_22-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (385 aa)
porBPyruvate-flavodoxin oxidoreductase. (1659 aa)
gcdB_2Carboxybiotin decarboxylase. (403 aa)
gcdB_3Glutaconyl-CoA decarboxylase subunit beta. (410 aa)
bclAAcetyl-coenzyme A synthetase. (540 aa)
lpd3Dihydrolipoyl dehydrogenase 3. (467 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (321 aa)
BVIR_2729Putative FAD-linked oxidoreductase. (467 aa)
tmeNADP-dependent malic enzyme. (759 aa)
accA_1Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (341 aa)
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
leuA_32-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa)
frdAFumarate reductase flavoprotein subunit. (588 aa)
frdBFumarate reductase iron-sulfur subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (250 aa)
frdCFumarate reductase subunit C. (150 aa)
frdDFumarate reductase subunit D. (121 aa)
pykPyruvate kinase; Belongs to the pyruvate kinase family. (477 aa)
pckGPhosphoenolpyruvate carboxykinase [GTP]; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (618 aa)
BVIR_3140Putative metallo-hydrolase. (218 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (317 aa)
thlA_1Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
acsA_1Acetyl-coenzyme A synthetase. (566 aa)
BVIR_4552-oxoglutarate oxidoreductase subunit KorB. (281 aa)
porA2-oxoglutarate oxidoreductase subunit KorA. (379 aa)
aceBMalate synthase A; Belongs to the malate synthase family. (999 aa)
gcdB_1Glutaconyl-CoA decarboxylase subunit beta. (376 aa)
leuA_12-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (531 aa)
Your Current Organism:
Blastochloris viridis
NCBI taxonomy Id: 1079
Other names: ATCC 19567, B. viridis, CCUG 30818, CCUG 7830, DSM 133, LMG 4321, LMG:4321, NBRC 102659, Rhodopseudomonas viridis, strain G. Drews F
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