(121 nodes) Mixed, incl. MAPK family signaling cascades, and Small GTPase mediated signal transduction network (Cordyceps confragosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LEL_06359	Protein kinase-like domain protein. (632 aa)
	LEL_06709	Phox-domain containing protein. (580 aa)
	LEL_02331	Uncharacterized protein. (815 aa)
	LEL_09868	Uncharacterized protein. (450 aa)
	LEL_09693	CDC24 calponin. (968 aa)
	LEL_09147	Uncharacterized protein. (801 aa)
	LEL_07010	Protein kinase-like domain protein. (260 aa)
	LEL_05716	Zinc finger, RING/FYVE/PHD-type. (556 aa)
	LEL_03975	Ras-2 protein. (236 aa)
	LEL_04255	14-3-3 protein. (310 aa)
	LEL_04226	Calcium channel subunit Mid1. (625 aa)
	LEL_02818	Uncharacterized protein. (450 aa)
	LEL_03268	Ras-like protein. (216 aa)
	LEL_03508	Rho guanyl nucleotide exchange factor. (292 aa)
	LEL_01597	Protein-tyrosine phosphatase 2. (451 aa)
	LEL_01897	14-3-3 domain protein; Belongs to the 14-3-3 family. (525 aa)
	LEL_02167	14-3-3 protein; Belongs to the 14-3-3 family. (264 aa)
	LEL_06262	Non-specific serine/threonine protein kinase. (638 aa)
	LEL_00901	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (362 aa)
	LEL_04091	Calcium/calmodulin-dependent/calcium-dependent protein kinase. (693 aa)
	LEL_01401	Uncharacterized protein. (532 aa)
	LEL_05241	Protein phosphatase 2C. (529 aa)
	LEL_05281	Heat-labile enterotoxin, A chain. (730 aa)
	LEL_02384	Activating transcription factor 7a. (291 aa)
	LEL_01463	Glycoside hydrolase, superfamily. (393 aa)
	LEL_09615	Src-domain containing protein; Belongs to the DOCK family. (2030 aa)
	LEL_08969	Ankyrin repeat-containing domain protein. (354 aa)
	LEL_08105	Uncharacterized protein. (417 aa)
	LEL_07062	Fungal transcriptional regulatory protein. (527 aa)
	LEL_10527	EST1_DNA_bind domain-containing protein. (733 aa)
	LEL_10547	Cell division control protein 42. (195 aa)
	LEL_08350	Small GTPase superfamily. (189 aa)
	LEL_07547	Clostridium neurotoxin, translocation. (931 aa)
	LEL_10943	Cell division control protein 42. (195 aa)
	LEL_10663	Uncharacterized protein. (184 aa)
	LEL_10542	Serine/threonine-protein kinase Sgk2. (954 aa)
	LEL_10544	Protein kinase-like domain protein. (754 aa)
	LEL_10595	Ankyrin repeat-containing domain protein. (506 aa)
	LEL_10348	Rho GTPase activator Rga. (1088 aa)
	LEL_10370	Dual specificity phosphatase, catalytic domain protein. (816 aa)
	LEL_09827	Low temperature essential 1. (1802 aa)
	LEL_09864	GTPase activating protein. (1219 aa)
	LEL_09936	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (418 aa)
	LEL_09963	Ankyrin. (170 aa)
	LEL_09966	Ankyrin repeat-containing domain protein. (687 aa)
	LEL_09558	Protein phosphatase 2C. (412 aa)
	LEL_09586	Heat-labile enterotoxin, A chain. (953 aa)
	LEL_09008	Lipase, secreted; Belongs to the AB hydrolase superfamily. Lipase family. (454 aa)
	LEL_09053	Uncharacterized protein. (321 aa)
	LEL_09183	Ras guanine nucleotide exchange factor. (1164 aa)
	LEL_08479	LIM domain containing protein. (719 aa)
	LEL_08520	Forkhead domain containing protein. (1112 aa)
	LEL_08671	Rho2. (211 aa)
	LEL_08038	Uncharacterized protein. (229 aa)
	LEL_08222	Non-specific serine/threonine protein kinase. (823 aa)
	LEL_08232	Serine/threonine protein kinase. (1193 aa)
	LEL_08296	Protein kinase domain-containing protein. (1280 aa)
	LEL_06914	Protein kinase-like domain protein. (261 aa)
	LEL_06919	Ribosomal protein S35, mitochondrial. (326 aa)
	LEL_07144	RacA. (195 aa)
	LEL_07154	SH3 domain protein. (511 aa)
	LEL_07174	RAS small monomeric GTPase. (217 aa)
	LEL_07223	Rho GTPase-activating protein domain protein. (848 aa)
	LEL_07262	Uncharacterized protein. (159 aa)
	LEL_07278	Polymyxin B resistance protein kinase. (639 aa)
	LEL_07422	Uncharacterized protein. (241 aa)
	LEL_07448	Uncharacterized protein. (794 aa)
	LEL_07513	Uncharacterized protein. (848 aa)
	LEL_07759	Uncharacterized protein. (420 aa)
	LEL_05769	Uncharacterized protein. (417 aa)
	LEL_06005	Dual specificity phosphatase, subgroup, catalytic domain protein. (700 aa)
	LEL_06015	Ras GTPase activator. (2529 aa)
	LEL_06027	Serine/threonine-protein kinase domain protein. (761 aa)
	LEL_06061	MAPKK kinase. (906 aa)
	LEL_06231	Uncharacterized protein. (237 aa)
	LEL_06270	Non-specific serine/threonine protein kinase. (689 aa)
	LEL_06330	Uncharacterized protein. (195 aa)
	LEL_06360	Protein kinase-like domain protein. (242 aa)
	LEL_06580	Src-domain containing protein; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (308 aa)
	LEL_04239	Uncharacterized protein. (623 aa)
	LEL_04270	Wings apart-like protein. (653 aa)
	LEL_04468	Glycogen synthase kinase 3; Belongs to the protein kinase superfamily. (413 aa)
	LEL_04534	MAP kinase kinase. (561 aa)
	LEL_04658	ABC transporter, ABCE. (609 aa)
	LEL_04693	MAP kinase kinase Ste7. (509 aa)
	LEL_05024	Vacuolar membrane protein. (381 aa)
	LEL_05264	Uncharacterized protein. (988 aa)
	LEL_05389	Tyrosine-protein phosphatase non-receptor type 6. (910 aa)
	LEL_02302	MAPKKK cascade protein kinase regulator Ste50. (475 aa)
	LEL_02315	Protein phosphatase 2C. (585 aa)
	LEL_02452	MARVEL-like domain protein. (167 aa)
	LEL_02482	Uncharacterized protein. (387 aa)
	LEL_02500	Non-specific serine/threonine protein kinase. (880 aa)
	LEL_02526	Protein RHO3. (212 aa)
	LEL_02542	Uncharacterized protein. (162 aa)
	LEL_02560	Heat shock factor (HSF)-type, DNA-binding protein. (717 aa)
	LEL_02759	Von Willebrand factor, type A. (749 aa)
	LEL_02886	WW/Rsp5/WWP domain protein. (296 aa)
	LEL_02943	Rho GTPase-activating protein domain protein. (1154 aa)
	LEL_03122	Cell division control protein 42. (198 aa)
	LEL_03269	Zn(2)-C6 fungal-type DNA-binding domain protein. (1265 aa)
	LEL_03373	PH domain containing protein. (418 aa)
	LEL_03435	Alternative oxidase. (357 aa)
	LEL_03517	14-3-3 protein; Belongs to the 14-3-3 family. (325 aa)
	LEL_03609	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1128 aa)
	LEL_03651	Rho-gdp dissociation inhibitor. (168 aa)
	LEL_03936	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (414 aa)
	LEL_00058	U-box domain-containing protein. (209 aa)
	LEL_00234	Ras guanine nucleotide exchange factor. (1201 aa)
	LEL_00262	WD40 repeat-like-containing domain protein. (235 aa)
	LEL_00498	Transcription factor, MADS-box. (640 aa)
	LEL_00629	Peptidase aspartic, catalytic; Belongs to the peptidase A1 family. (882 aa)
	LEL_00786	Sin3 complex subunit Stb2. (884 aa)
	LEL_00924	Uncharacterized protein. (476 aa)
	LEL_01179	Uncharacterized protein. (574 aa)
	LEL_01370	Signal transduction response regulator, SKN7-like protein. (586 aa)
	LEL_01378	Uncharacterized protein. (263 aa)
	LEL_01416	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (376 aa)
	LEL_01558	Mitogen activated protein kinase kinase kinase 3, mapkkk3, mekk3. (1520 aa)
	LEL_02089	RhoGAP domain-containing protein. (1535 aa)
	LEL_02160	ELMO/CED-12 family protein. (724 aa)

Your Current Organism:

Cordyceps confragosa

NCBI taxonomy Id: 1081108
Other names: C. confragosa RCEF 1005, Cordyceps confragosa RCEF 1005

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LEL_00058	LEL_00262	A0A168JJ91	A0A168JPT7	U-box domain-containing protein.	WD40 repeat-like-containing domain protein.	0.466
LEL_00058	LEL_00786	A0A168JJ91	A0A168K530	U-box domain-containing protein.	Sin3 complex subunit Stb2.	0.418
LEL_00058	LEL_00901	A0A168JJ91	A0A162KMR8	U-box domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.475
LEL_00058	LEL_01179	A0A168JJ91	A0A168KFV6	U-box domain-containing protein.	Uncharacterized protein.	0.611
LEL_00058	LEL_01370	A0A168JJ91	A0A168KKI7	U-box domain-containing protein.	Signal transduction response regulator, SKN7-like protein.	0.676
LEL_00058	LEL_01378	A0A168JJ91	A0A168KKP9	U-box domain-containing protein.	Uncharacterized protein.	0.441
LEL_00058	LEL_01416	A0A168JJ91	A0A168KLY1	U-box domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.475
LEL_00058	LEL_01463	A0A168JJ91	A0A162KZ08	U-box domain-containing protein.	Glycoside hydrolase, superfamily.	0.465
LEL_00058	LEL_01597	A0A168JJ91	A0A162KG99	U-box domain-containing protein.	Protein-tyrosine phosphatase 2.	0.441
LEL_00058	LEL_01897	A0A168JJ91	A0A162KH29	U-box domain-containing protein.	14-3-3 domain protein; Belongs to the 14-3-3 family.	0.561
LEL_00058	LEL_02167	A0A168JJ91	A0A162KHP6	U-box domain-containing protein.	14-3-3 protein; Belongs to the 14-3-3 family.	0.561
LEL_00058	LEL_02315	A0A168JJ91	A0A168I6H3	U-box domain-containing protein.	Protein phosphatase 2C.	0.433
LEL_00058	LEL_02452	A0A168JJ91	A0A168I9U2	U-box domain-containing protein.	MARVEL-like domain protein.	0.441
LEL_00058	LEL_02500	A0A168JJ91	A0A168IB19	U-box domain-containing protein.	Non-specific serine/threonine protein kinase.	0.510
LEL_00058	LEL_02526	A0A168JJ91	A0A168IBP2	U-box domain-containing protein.	Protein RHO3.	0.466
LEL_00058	LEL_02542	A0A168JJ91	A0A168IBW7	U-box domain-containing protein.	Uncharacterized protein.	0.453
LEL_00058	LEL_02560	A0A168JJ91	A0A168ICC7	U-box domain-containing protein.	Heat shock factor (HSF)-type, DNA-binding protein.	0.436
LEL_00058	LEL_02886	A0A168JJ91	A0A168ILF7	U-box domain-containing protein.	WW/Rsp5/WWP domain protein.	0.406
LEL_00058	LEL_02943	A0A168JJ91	A0A168IN07	U-box domain-containing protein.	Rho GTPase-activating protein domain protein.	0.445
LEL_00058	LEL_03122	A0A168JJ91	A0A168ITC5	U-box domain-containing protein.	Cell division control protein 42.	0.466