Your Input: | |
| | GNIT_0235 | Gluconolactonase. (290 aa) |
| | GNIT_0283 | Dimethylmenaquinone methyltransferase. (206 aa) |
| | GNIT_0297 | FMN-dependent alpha-hydroxy acid dehydrogenase. (381 aa) |
| | fbp | Fructose-1,6-bisphosphatase. (322 aa) |
| | fdxA | Putative ferredoxin; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (75 aa) |
| | rpe | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (220 aa) |
| | sfcA | Malate dehydrogenase. (564 aa) |
| | gpm | Phosphoglycerate mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa) |
| | GNIT_0596 | Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa) |
| | GNIT_0627 | NAD-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (469 aa) |
| | acnB | Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (870 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (869 aa) |
| | leuD | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa) |
| | leuC | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (750 aa) |
| | GNIT_0993 | Isocitrate lyase. (533 aa) |
| | GNIT_1138 | Hypothetical protein. (81 aa) |
| | GNIT_1151 | Putative alpha-amylase. (380 aa) |
| | ilvE | Branched-chain amino acid aminotransferase. (332 aa) |
| | GNIT_1367 | LacI family transcription regulator. (355 aa) |
| | pycB | Pyruvate carboxylase subunit B. (681 aa) |
| | dld | D-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (584 aa) |
| | GNIT_1617 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa) |
| | pgm | Phosphoglucomutase. (548 aa) |
| | GNIT_1629 | Putative maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (419 aa) |
| | GNIT_1743 | Aminotransferase AlaT. (404 aa) |
| | GNIT_1746 | Putative sucrose phosphorylase. (594 aa) |
| | GNIT_1847 | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (322 aa) |
| | bkdB | Dihydrolipoamide acetyltransferase. (564 aa) |
| | bkdA2 | 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (325 aa) |
| | bkdA1 | 3-methyl-2-oxobutanoate dehydrogenase (lipoamide). (395 aa) |
| | fumA | Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (510 aa) |
| | mmsA | Methylmalonate-semialdehyde dehydrogenase. (496 aa) |
| | GNIT_2024 | Putative pullulanase; Belongs to the glycosyl hydrolase 13 family. (1464 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | GNIT_2028 | Dihydrolipoyltranssuccinate transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (500 aa) |
| | GNIT_2029 | 2-oxoglutarate decarboxylase. (942 aa) |
| | sdhB | Succinate dehydrogenase catalytic subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa) |
| | sdhA | Succinate dehydrogenase catalytic subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa) |
| | sdhD | Putative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhC | Succinate dehydrogenase, cytochrome b subunit. (92 aa) |
| | GNIT_2034 | Citrate synthase; Belongs to the citrate synthase family. (426 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa) |
| | GNIT_2098 | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (494 aa) |
| | GNIT_2101 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (519 aa) |
| | glgX | Glycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (747 aa) |
| | glgB | Glycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (731 aa) |
| | malQ | 4-alpha-glucanotransferase. (731 aa) |
| | GNIT_2105 | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | GNIT_2106 | Aldose 1-epimerase; Belongs to the glucose-6-phosphate 1-epimerase family. (292 aa) |
| | eda | Keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase. (211 aa) |
| | glk | Glucokinase; Belongs to the bacterial glucokinase family. (319 aa) |
| | edd | Phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (230 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (502 aa) |
| | GNIT_2112 | DNA-binding transcriptional regulator HexR. (283 aa) |
| | GNIT_2113 | Pyruvate kinase II; Belongs to the pyruvate kinase family. (482 aa) |
| | icd | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | pdxB | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (382 aa) |
| | GNIT_2202 | Hypothetical protein. (36 aa) |
| | GNIT_2308 | Glu/Leu/Phe/Val dehydrogenase, dimerization region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (304 aa) |
| | oadB | Oxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa) |
| | oadA | Oxaloacetate decarboxylase. (593 aa) |
| | oadG | Putative oxaloacetate decarboxylase subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (94 aa) |
| | GNIT_2478 | Isocitrate dehydrogenase. (337 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (433 aa) |
| | ilvE-2 | Branched-chain amino acid aminotransferase, putative. (306 aa) |
| | GNIT_2620 | Branched-chain amino acid aminotransferase-like protein. (246 aa) |
| | GNIT_2625 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa) |
| | fumC | Fumarate hydratase. (435 aa) |
| | rbsK | Sugar kinase, ribokinase family protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (297 aa) |
| | rpiA | Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (217 aa) |
| | GNIT_2671 | Dihydrolipoamide dehydrogenase. (472 aa) |
| | GNIT_2672 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (592 aa) |
| | aceE | Pyruvate dehydrogenase (decarboxylase component, E1); Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa) |
| | GNIT_2727 | Fructose-1,6-bisphosphate aldolase. (299 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (389 aa) |
| | epd | D-erythrose-4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (337 aa) |
| | GNIT_2730 | Transketolase 1; Belongs to the transketolase family. (664 aa) |
| | tal | Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | pgi | Glucose-6-phosphate isomerase; Belongs to the GPI family. (545 aa) |
| | acsA | Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (647 aa) |
| | ldhA | D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (381 aa) |
| | ilvB | Acetolactate synthase; Belongs to the TPP enzyme family. (546 aa) |
| | GNIT_2866 | Catalytic domain of components of various dehydrogenase complexes. (423 aa) |
| | GNIT_2867 | Pyruvate dehydrogenase complex, E1 beta2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa) |
| | GNIT_2868 | Pyruvate dehydrogenase (acetyl-transferring). (272 aa) |
| | GNIT_2869 | acetyl-CoA synthetase. (583 aa) |
| | maeB | NADP-dependent malic enzyme. (416 aa) |
| | ilvH | Acetolactate synthase III, small subunit. (165 aa) |
| | ilvB-2 | Acetolactate synthase III large subunit. (571 aa) |
| | GNIT_3070 | Alpha amylase, catalytic region. (688 aa) |
| | GNIT_3153 | GntR family transcriptional regulator. (218 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (292 aa) |
| | GNIT_3155 | Methylcitrate synthase; Belongs to the citrate synthase family. (373 aa) |
| | GNIT_3156 | Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (862 aa) |
| | GNIT_3157 | AcnD-accessory protein PrpF. (391 aa) |
| | leuD-2 | Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa) |
| | leuC-2 | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (470 aa) |
| | GNIT_3249 | Putative dehydrogenase, NAD(P)-binding domain and GroES-like domain protein. (328 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (537 aa) |
| | prpE | propionyl-CoA synthetase. (634 aa) |
| | GNIT_3372 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (559 aa) |
| | prpD | 2-methylcitrate dehydratase. (495 aa) |
| | GNIT_3412 | Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase. (470 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (395 aa) |
| | GNIT_3426 | 3-isopropylmalate dehydratase, putative; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa) |
| | leuC-3 | Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (459 aa) |
| | GNIT_3429 | Citrate synthase. (264 aa) |
| | GNIT_3512 | Malate synthase G. (334 aa) |
| | ilvD-2 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (615 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (494 aa) |
