STRINGSTRING
GNIT_0297 GNIT_0297 ppc ppc leuD leuD leuC leuC leuB leuB leuA leuA pycB pycB dld dld GNIT_1617 GNIT_1617 GNIT_2113 GNIT_2113 oadB oadB oadA oadA oadG oadG ldhA ldhA maeB maeB leuD-2 leuD-2 leuC-2 leuC-2 pckA pckA GNIT_3372 GNIT_3372 GNIT_3426 GNIT_3426 leuC-3 leuC-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNIT_0297FMN-dependent alpha-hydroxy acid dehydrogenase. (381 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (869 aa)
leuDIsopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (466 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (362 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa)
pycBPyruvate carboxylase subunit B. (681 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (584 aa)
GNIT_1617Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
GNIT_2113Pyruvate kinase II; Belongs to the pyruvate kinase family. (482 aa)
oadBOxaloacetate decarboxylase, beta subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the GcdB/MmdB/OadB family. (376 aa)
oadAOxaloacetate decarboxylase. (593 aa)
oadGPutative oxaloacetate decarboxylase subunit gamma; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation. (94 aa)
ldhAD-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein. (381 aa)
maeBNADP-dependent malic enzyme. (416 aa)
leuD-2Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
leuC-2Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (467 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (537 aa)
GNIT_3372Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa)
GNIT_34263-isopropylmalate dehydratase, putative; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa)
leuC-3Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (459 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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