STRINGSTRING
ubiC ubiC ubiA ubiA GNIT_0397 GNIT_0397 lcyB lcyB crtB crtB crtI crtI GNIT_0401 GNIT_0401 GNIT_0402 GNIT_0402 prlC prlC GNIT_0601 GNIT_0601 ubiE ubiE GNIT_0603 GNIT_0603 ubiB ubiB menA menA GNIT_0850 GNIT_0850 gcpE gcpE xseA xseA lytB lytB dxs dxs ispA ispA xseB xseB GNIT_1114 GNIT_1114 hmg1 hmg1 GNIT_1295 GNIT_1295 pcm pcm GNIT_1297 GNIT_1297 GNIT_1538 GNIT_1538 ubiG ubiG ispE ispE ubiF ubiF dxr dxr GNIT_2657 GNIT_2657 ispD ispD ispF ispF ispB ispB ubiG-2 ubiG-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
ubiCPutative chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (196 aa)
ubiA4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (287 aa)
GNIT_0397Hypothetical protein; Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal. Belongs to the Brp/Blh beta-carotene diooxygenase family. (291 aa)
lcyBPutative FAD dependent oxidoreductase. (409 aa)
crtBPhytoene synthase. (313 aa)
crtIPhytoene dehydrogenase. (490 aa)
GNIT_0401Polyprenyl synthetase family protein; Belongs to the FPP/GGPP synthase family. (285 aa)
GNIT_0402Bacteriorhodopsin. (275 aa)
prlCOligopeptidase A. (676 aa)
GNIT_06013-methyl-adenine DNA glycosylase. (241 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (277 aa)
GNIT_0603Hypothetical protein. (234 aa)
ubiB2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. (542 aa)
menAUbiA prenyltransferase. (327 aa)
GNIT_0850AFG1 family ATPase. (510 aa)
gcpE4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (373 aa)
xseAExodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (451 aa)
lytBHydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (313 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (619 aa)
ispAGeranyltranstransferase; Belongs to the FPP/GGPP synthase family. (304 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (90 aa)
GNIT_1114Hypothetical protein. (64 aa)
hmg1Hydroxymethylglutaryl-coenzyme A reductase. (513 aa)
GNIT_1295Hypothetical protein. (153 aa)
pcmprotein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. (661 aa)
GNIT_1297Hypothetical protein. (395 aa)
GNIT_1538Metallo-beta-lactamase family protein. (437 aa)
ubiGUbiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (236 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)
ubiF2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. (387 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (403 aa)
GNIT_26572-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase. (401 aa)
ispD4-phosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (256 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa)
ispBGeranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (323 aa)
ubiG-22-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4- benzoquinol methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (257 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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