STRINGSTRING
GNIT_3253 GNIT_3253 GNIT_3429 GNIT_3429 GNIT_3512 GNIT_3512 coxC coxC coxA coxA GNIT_3632 GNIT_3632 nqrE nqrE glcB glcB GNIT_1151 GNIT_1151 ppc ppc nqrB nqrB ccoP ccoP ccoN ccoN GNIT_1911 GNIT_1911 GNIT_1932 GNIT_1932 GNIT_2024 GNIT_2024 sucD sucD sucC sucC GNIT_2028 GNIT_2028 GNIT_2029 GNIT_2029 sdhB sdhB sdhA sdhA sdhD sdhD sdhC sdhC GNIT_2034 GNIT_2034 glgX glgX glgB glgB mdh mdh mnhD mnhD mnhD-2 mnhD-2 mnhD-3 mnhD-3 ndhF ndhF dld dld GNIT_1614 GNIT_1614 GNIT_1665 GNIT_1665 cydB cydB cydA cydA glgC glgC cybB cybB ubiE ubiE acnB acnB GNIT_0729 GNIT_0729 icd icd GNIT_2170 GNIT_2170 phaD phaD phaA phaA GNIT_2625 GNIT_2625 fumC fumC aceK aceK GNIT_2876 GNIT_2876 GNIT_2943 GNIT_2943 GNIT_2951 GNIT_2951 GNIT_3155 GNIT_3155 GNIT_3156 GNIT_3156 glgA glgA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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GNIT_3253Malate synthase. (150 aa)
GNIT_3429Citrate synthase. (264 aa)
GNIT_3512Malate synthase G. (334 aa)
coxCCytochrome c oxidase subunit III. (299 aa)
coxACytochrome-c oxidase; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (536 aa)
GNIT_3632High-potential iron sulfur protein isozyme-2, HiPIP-2. (97 aa)
nqrENa(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (202 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (750 aa)
GNIT_1151Putative alpha-amylase. (380 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (869 aa)
nqrBNa(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (403 aa)
ccoPCytochrome c oxidase, cbb3-type, subunit III; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. (318 aa)
ccoNCytochrome c oxidase, cbb3-type, subunit I; Belongs to the heme-copper respiratory oxidase family. (477 aa)
GNIT_1911Methyltransferase type 11. (211 aa)
GNIT_1932Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. (549 aa)
GNIT_2024Putative pullulanase; Belongs to the glycosyl hydrolase 13 family. (1464 aa)
sucDsuccinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
GNIT_2028Dihydrolipoyltranssuccinate transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (500 aa)
GNIT_20292-oxoglutarate decarboxylase. (942 aa)
sdhBSuccinate dehydrogenase catalytic subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (236 aa)
sdhASuccinate dehydrogenase catalytic subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
sdhDPutative succinate dehydrogenase, hydrophobic subunit, cytochrome b556 with sdhC; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa)
sdhCSuccinate dehydrogenase, cytochrome b subunit. (92 aa)
GNIT_2034Citrate synthase; Belongs to the citrate synthase family. (426 aa)
glgXGlycogen debranching enzyme GlgX; Belongs to the glycosyl hydrolase 13 family. (747 aa)
glgBGlycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (731 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
mnhDPutative monovalent cation/H+ antiporter subunit D. (568 aa)
mnhD-2NADH dehydrogenase (quinone). (513 aa)
mnhD-3NADH dehydrogenase/oxidoreductase. (496 aa)
ndhFNADH dehydrogenase subunit L. (526 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (584 aa)
GNIT_1614Putative oligoketide cyclase/lipid transport protein. (143 aa)
GNIT_1665Hypothetical protein. (211 aa)
cydBPutative quinol oxidase subunit ii transmembrane protein. (333 aa)
cydAPutative transmembrane cytochrome bd-ii oxidase (subunit i) oxidoreductase protein. (465 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (419 aa)
cybBCytochrome B561. (192 aa)
ubiEUbiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (277 aa)
acnBBifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (870 aa)
GNIT_0729Ubiquinol-cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (421 aa)
icdIsocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (742 aa)
GNIT_2170Cytochrome b561 family protein. (229 aa)
phaDNADH dehydrogenase subunit N. (508 aa)
phaANADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit. (929 aa)
GNIT_2625Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (903 aa)
fumCFumarate hydratase. (435 aa)
aceKBifunctional isocitrate dehydrogenase kinase/phosphatase protein; Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation. (623 aa)
GNIT_2876Lysine 2,3-aminomutase YodO family protein. (355 aa)
GNIT_2943Formate dehydrogenase; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (718 aa)
GNIT_2951Cytochrome b561 family protein. (239 aa)
GNIT_3155Methylcitrate synthase; Belongs to the citrate synthase family. (373 aa)
GNIT_3156Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (862 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (470 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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