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rfbA rfbA mdoH mdoH mdoG mdoG GNIT_3372 GNIT_3372 glmU glmU pckA pckA GNIT_3231 GNIT_3231 GNIT_3230 GNIT_3230 GNIT_3229 GNIT_3229 glgA glgA GNIT_3122 GNIT_3122 GNIT_3119 GNIT_3119 GNIT_3097 GNIT_3097 GNIT_3096 GNIT_3096 rfbA-2 rfbA-2 rfbD-2 rfbD-2 pgi pgi lpxC lpxC GNIT_2597 GNIT_2597 htrB htrB GNIT_2570 GNIT_2570 GNIT_2569 GNIT_2569 GNIT_2567 GNIT_2567 GNIT_2564 GNIT_2564 GNIT_2562 GNIT_2562 GNIT_2560 GNIT_2560 GNIT_2559 GNIT_2559 GNIT_2555 GNIT_2555 GNIT_2553 GNIT_2553 GNIT_2552 GNIT_2552 GNIT_2551 GNIT_2551 GNIT_0053 GNIT_0053 kdkA kdkA opsX opsX GNIT_0235 GNIT_0235 fbp fbp GNIT_0382 GNIT_0382 wbpO wbpO GNIT_0860 GNIT_0860 kdsC kdsC eptA eptA lpxD lpxD GNIT_1151 GNIT_1151 GNIT_1279 GNIT_1279 GNIT_1306 GNIT_1306 maa maa lpxH lpxH GNIT_1617 GNIT_1617 GNIT_1684 GNIT_1684 glgC glgC GNIT_1747 GNIT_1747 sdaA sdaA manC manC kdsB kdsB lpxK lpxK tpiA tpiA glgB glgB kdsA kdsA GNIT_2252 GNIT_2252 GNIT_2253 GNIT_2253 GNIT_2260 GNIT_2260 neuA neuA GNIT_2381 GNIT_2381 neuB neuB GNIT_2390 GNIT_2390 neuA-2 neuA-2 GNIT_2392 GNIT_2392 GNIT_2393 GNIT_2393 GNIT_2394 GNIT_2394 lpxB lpxB lpxA lpxA fabZ fabZ ugd ugd GNIT_2482 GNIT_2482 GNIT_2483 GNIT_2483 wecC wecC GNIT_2504 GNIT_2504 GNIT_2506 GNIT_2506 GNIT_2529 GNIT_2529 rfbD rfbD GNIT_2547 GNIT_2547 GNIT_3611 GNIT_3611
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
mdoHGlucosyltransferase MdoH. (681 aa)
mdoGGlucans biosynthesis protein G precursor; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (528 aa)
GNIT_3372Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (794 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (452 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (537 aa)
GNIT_3231Putative glycosyl hydrolase. (295 aa)
GNIT_3230Putative glycosyl hydrolase. (314 aa)
GNIT_3229Glycosyl hydrolases family 17. (318 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (470 aa)
GNIT_3122Glycosyl transferase family protein. (588 aa)
GNIT_3119Hypothetical protein. (625 aa)
GNIT_3097O-antigen biosynthesis protein; Putative bifunctional glycosyltransferase, forming alpha-glycosyl and beta-glycosyl linkages protein. (571 aa)
GNIT_3096Glycosyl transferase group 1. (403 aa)
rfbA-2Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
rfbD-2dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (302 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (545 aa)
lpxCUDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (304 aa)
GNIT_2597Glycosyltransferase. (421 aa)
htrBLipid A biosynthesis lauroyl acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (361 aa)
GNIT_2570Putative exopolysaccharide biosynthesis protein. (348 aa)
GNIT_2569Lipopolysaccharide biosynthesis. (525 aa)
GNIT_2567Bacterial sugar transferase domain protein. (470 aa)
GNIT_2564Glycosyl transferase, group 1. (403 aa)
GNIT_2562Glycosyltransferase. (385 aa)
GNIT_2560Membrane-anchored group 1 glycosyltransferase. (409 aa)
GNIT_2559Glycosyl transferase group 1. (389 aa)
GNIT_2555Putative acetyltransferase. (358 aa)
GNIT_2553Polysaccharide biosynthesis protein. (493 aa)
GNIT_2552Putative glycosyltransferase. (314 aa)
GNIT_2551Hypothetical protein. (356 aa)
GNIT_0053Glycosyl transferase, family 25. (248 aa)
kdkA3-deoxy-D-manno-octulosonic-acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family. (280 aa)
opsXPutative ADP-heptose:LPS heptosyltransferase. (348 aa)
GNIT_0235Gluconolactonase. (290 aa)
fbpFructose-1,6-bisphosphatase. (322 aa)
GNIT_03823-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (435 aa)
wbpOVI polysaccharide biosynthesis protein VipA/tviB; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (415 aa)
GNIT_0860Hypothetical protein. (314 aa)
kdsC3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (184 aa)
eptAPutative sulfatase. (575 aa)
lpxDGlucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (339 aa)
GNIT_1151Putative alpha-amylase. (380 aa)
GNIT_1279Hypothetical protein. (610 aa)
GNIT_1306Alcohol dehydrogenase, iron-containing. (366 aa)
maaHexapeptide repeat-containing transferase. (186 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (241 aa)
GNIT_1617Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
GNIT_1684Putative glycosyltransferase. (439 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (419 aa)
GNIT_1747Mannosyl-3-phosphoglycerate phosphatase. (294 aa)
sdaAL-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa)
manCMannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family. (472 aa)
kdsB3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (251 aa)
lpxKTetraacyldisaccharide 4-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (326 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (246 aa)
glgBGlycogen branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (731 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. (279 aa)
GNIT_2252Hypothetical protein. (201 aa)
GNIT_2253Hypothetical protein. (279 aa)
GNIT_2260Hypothetical protein. (184 aa)
neuAPutative CMP-N-acetlyneuraminic acid synthetase. (383 aa)
GNIT_2381Hypothetical protein. (301 aa)
neuBN-acylneuraminate-9-phosphate synthase. (359 aa)
GNIT_2390Hypothetical protein. (322 aa)
neuA-2Acylneuraminate cytidylyltransferase. (234 aa)
GNIT_2392DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (399 aa)
GNIT_2393Polysaccharide biosynthesis protein CapD. (332 aa)
GNIT_2394Hypothetical protein. (1245 aa)
lpxBtetraacyldisaccharide-1-P synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (393 aa)
lpxAacyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (256 aa)
fabZ(3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (148 aa)
ugdUDP-glucose 6-dehydrogenase. (446 aa)
GNIT_2482Polysaccharide biosynthesis protein. (577 aa)
GNIT_2483Sugar transferase. (182 aa)
wecCUDP-N-acetyl-D-mannosaminuronate dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (425 aa)
GNIT_2504Glycosyl transferase, family 39. (576 aa)
GNIT_2506Glycosyl transferase family protein. (246 aa)
GNIT_2529Protein involved in cellulose biosynthesis (CelD)-like protein. (684 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (293 aa)
GNIT_2547Hypothetical protein. (218 aa)
GNIT_3611Putative iron-containing alcohol dehydrogenase. (392 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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