STRINGSTRING
GNIT_3616 GNIT_3616 GNIT_0043 GNIT_0043 coaBC coaBC tdh tdh paaG paaG GNIT_0113 GNIT_0113 fadN fadN GNIT_0152 GNIT_0152 GNIT_0153 GNIT_0153 GNIT_0230 GNIT_0230 GNIT_0252 GNIT_0252 GNIT_0283 GNIT_0283 GNIT_0292 GNIT_0292 fadH fadH GNIT_0326 GNIT_0326 GNIT_0450 GNIT_0450 astD astD astA astA dtd dtd murQ murQ GNIT_0778 GNIT_0778 GNIT_0957 GNIT_0957 fadA fadA fadJ fadJ GNIT_1385 GNIT_1385 GNIT_1395 GNIT_1395 GNIT_1396 GNIT_1396 GNIT_1557 GNIT_1557 fadN-2 fadN-2 GNIT_1603 GNIT_1603 GNIT_1619 GNIT_1619 astE astE GNIT_1687 GNIT_1687 GNIT_1695 GNIT_1695 GNIT_1701 GNIT_1701 astB astB fadE fadE ald ald garR garR GNIT_1881 GNIT_1881 bkdA2 bkdA2 bkdA1 bkdA1 mmsB mmsB paaG-4 paaG-4 GNIT_2028 GNIT_2028 GNIT_2101 GNIT_2101 edd edd anmK anmK fadH-2 fadH-2 GNIT_2218 GNIT_2218 GNIT_2311 GNIT_2311 phhA phhA paaK paaK GNIT_2580 GNIT_2580 GNIT_2584 GNIT_2584 kynU kynU gcvP gcvP gcvH gcvH gcvT gcvT GNIT_2683 GNIT_2683 GNIT_2816 GNIT_2816 GNIT_2867 GNIT_2867 GNIT_2868 GNIT_2868 GNIT_2876 GNIT_2876 GNIT_2891 GNIT_2891 putA putA fadB fadB fadA-2 fadA-2 prpB prpB GNIT_3157 GNIT_3157 GNIT_3171 GNIT_3171 GNIT_3182 GNIT_3182 GNIT_3254 GNIT_3254 GNIT_3328 GNIT_3328 GNIT_3332 GNIT_3332 speA speA GNIT_3499 GNIT_3499 slyX slyX GNIT_3531 GNIT_3531 GNIT_3598 GNIT_3598 GNIT_3612 GNIT_3612
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GNIT_3616phytanoyl-CoA dioxygenase. (278 aa)
GNIT_0043Putative metallo hydrolase. (373 aa)
coaBCPhosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (421 aa)
tdhL-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (354 aa)
paaGenoyl-CoA hydratase. (287 aa)
GNIT_0113acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
fadNFatty oxidation complex, alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family. (702 aa)
GNIT_0152Mandelate racemase/muconate lactonizing enzyme family protein. (391 aa)
GNIT_0153Amidohydrolase 2. (324 aa)
GNIT_0230Beta-ketothiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
GNIT_0252Amine oxidase. (392 aa)
GNIT_0283Dimethylmenaquinone methyltransferase. (206 aa)
GNIT_0292Cytochrome oxidase maturation protein cbb3-type. (387 aa)
fadH2,4-dienoyl-CoA reductase. (675 aa)
GNIT_0326Thioesterase superfamily protein. (132 aa)
GNIT_0450Succinylglutamate desuccinylase/aspartoacylase. (341 aa)
astDSuccinylglutamic semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (490 aa)
astAArginine N-succinyltransferase. (344 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (145 aa)
murQGlucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. (306 aa)
GNIT_0778Putative metal-dependent amidohydrolase with the TIM-barrel fold protein. (560 aa)
GNIT_0957Amidohydrolase. (589 aa)
fadA3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa)
fadJMultifunctional fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities. Belongs to the enoyl-CoA hydratase/isomerase family. In the central section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (702 aa)
GNIT_1385Putative metal-dependent hydrolase. (189 aa)
GNIT_1395Amidohydrolase family protein. (470 aa)
GNIT_1396Amidohydrolase. (430 aa)
GNIT_1557Aminoglycoside phosphotransferase. (352 aa)
fadN-23-hydroxyacyl-CoA dehydrogenase, NAD-binding protein. (704 aa)
GNIT_1603Hypothetical protein. (253 aa)
GNIT_1619FAD binding protein. (1039 aa)
astESuccinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (340 aa)
GNIT_1687Putative acyl-CoA thioesterase, TesB family protein. (267 aa)
GNIT_1695Pyruvate carboxyltransferase. (299 aa)
GNIT_1701acetyl-CoA acetyltransferase with thiolase domain; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
astBSuccinylarginine dihydrolase; Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)- succinylornithine, ammonia and CO(2). (445 aa)
fadEacyl-CoA dehydrogenase. (826 aa)
aldAlanine dehydrogenase; Belongs to the AlaDH/PNT family. (376 aa)
garR2-hydroxy-3-oxopropionate reductase. (290 aa)
GNIT_1881NAD-specific glutamate dehydrogenase. (1612 aa)
bkdA22-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit. (325 aa)
bkdA13-methyl-2-oxobutanoate dehydrogenase (lipoamide). (395 aa)
mmsB3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (295 aa)
paaG-4enoyl-CoA hydratase/carnithine racemase. (391 aa)
GNIT_2028Dihydrolipoyltranssuccinate transferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (500 aa)
GNIT_21016-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (519 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (609 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (395 aa)
fadH-2NADH:flavin oxidoreductase/NADH oxidase. (677 aa)
GNIT_2218Fumarylacetoacetate (FAA) hydrolase. (240 aa)
GNIT_23112-keto-4-pentenoate hydratase. (337 aa)
phhAPhenylalanine 4-monooxygenase. (270 aa)
paaKPutative CapK protein. (448 aa)
GNIT_2580acyl-CoA dehydrogenase. (757 aa)
GNIT_2584Aminoglycoside phosphotransferase. (356 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (459 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (974 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTGlycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. (360 aa)
GNIT_2683Aspartoacylase. (299 aa)
GNIT_2816Histidine triad (HIT) protein. (120 aa)
GNIT_2867Pyruvate dehydrogenase complex, E1 beta2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (331 aa)
GNIT_2868Pyruvate dehydrogenase (acetyl-transferring). (272 aa)
GNIT_2876Lysine 2,3-aminomutase YodO family protein. (355 aa)
GNIT_2891Amidohydrolase. (1110 aa)
putABifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1266 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
fadA-23-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (386 aa)
prpB2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (292 aa)
GNIT_3157AcnD-accessory protein PrpF. (391 aa)
GNIT_3171acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
GNIT_3182hydroxymethylglutaryl-CoA lyase. (304 aa)
GNIT_3254Amidohydrolase. (426 aa)
GNIT_3328Phytanoyl-CoA dioxygenase superfamily. (234 aa)
GNIT_3332Amidohydrolase. (498 aa)
speAArginine decarboxylase; Catalyzes the biosynthesis of agmatine from arginine. Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. (641 aa)
GNIT_3499Alpha/beta hydrolase fold protein. (351 aa)
slyXPutative slyX protein (slyX). (83 aa)
GNIT_3531Amidohydrolase 3. (543 aa)
GNIT_3598Xaa-Pro dipeptidase family enzyme. (436 aa)
GNIT_3612Thioesterase superfamily protein. (140 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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