STRINGSTRING
kbl kbl GNIT_0139 GNIT_0139 lysA lysA GNIT_0325 GNIT_0325 hemL hemL argD argD patB patB GNIT_0637 GNIT_0637 ilvA ilvA GNIT_0834 GNIT_0834 iscS iscS glyA glyA dxs dxs hisC hisC GNIT_1182 GNIT_1182 GNIT_1297 GNIT_1297 bioA bioA bioF bioF sufS sufS hisC-2 hisC-2 GNIT_1465 GNIT_1465 GNIT_1481 GNIT_1481 GNIT_1629 GNIT_1629 sufS-2 sufS-2 pabC pabC GNIT_1743 GNIT_1743 serC serC metB metB aspC aspC GNIT_2029 GNIT_2029 GNIT_2090 GNIT_2090 metH metH kynU kynU GNIT_2745 GNIT_2745 GNIT_2755 GNIT_2755 GNIT_2832 GNIT_2832 ilvB ilvB metY metY ilvB-2 ilvB-2 gadB gadB GNIT_3169 GNIT_3169 GNIT_3239 GNIT_3239 ilvA-2 ilvA-2 GNIT_3610 GNIT_3610
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)
GNIT_0139Methionine gamma-lyase. (432 aa)
lysAPutative diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (416 aa)
GNIT_03252OG-Fe(II) oxygenase. (234 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase. (430 aa)
argDBifunctional N-succinyldiaminopimelate- aminotransferase/acetylornithine transaminase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
patBAminotransferase. (374 aa)
GNIT_0637Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (359 aa)
ilvAThreonine dehydratase. (335 aa)
GNIT_0834Pyridoxal-dependent decarboxylase. (468 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (407 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
dxsDeoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (619 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
GNIT_1182Aminotransferase. (477 aa)
GNIT_1297Hypothetical protein. (395 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (426 aa)
bioF8-amino-7-oxononanoate synthase. (420 aa)
sufSSelenocysteine lyase/Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (405 aa)
hisC-2Putative aminotransferase. (388 aa)
GNIT_1465Hypothetical protein. (229 aa)
GNIT_1481Oxidoreductase, 2OG-Fe(II) oxygenase family. (227 aa)
GNIT_1629Putative maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
sufS-2SufS subfamily cysteine desulfurase. (606 aa)
pabC4-amino-4-deoxychorismate lyase. (294 aa)
GNIT_1743Aminotransferase AlaT. (404 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (363 aa)
metBO-acetylhomoserine (thiol)-lyase. (416 aa)
aspCAromatic amino acid aminotransferase. (396 aa)
GNIT_20292-oxoglutarate decarboxylase. (942 aa)
GNIT_2090Cystathionine gamma-lyase. (370 aa)
metHB12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (893 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (459 aa)
GNIT_2745Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (229 aa)
GNIT_2755Threonine synthase. (427 aa)
GNIT_2832Methionine gamma-lyase. (422 aa)
ilvBAcetolactate synthase; Belongs to the TPP enzyme family. (546 aa)
metYO-acetylhomoserine sulfhydrylase. (429 aa)
ilvB-2Acetolactate synthase III large subunit. (571 aa)
gadBGlutamate decarboxylase putative. (540 aa)
GNIT_3169MOSC domain containing protein. (207 aa)
GNIT_3239Aminotransferase, class V. (375 aa)
ilvA-2Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (531 aa)
GNIT_36102OG-Fe(II) oxygenase. (226 aa)
Your Current Organism:
Glaciecola nitratireducens
NCBI taxonomy Id: 1085623
Other names: G. nitratireducens FR1064, Glaciecola nitratireducens FR1064, Glaciecola nitratireducens str. FR1064, Glaciecola nitratireducens strain FR1064, Glaciecola sp. FR1064
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