STRINGSTRING
SPB1 SPB1 ABOM_012062 ABOM_012062 ABOM_012244 ABOM_012244 ABOM_011963 ABOM_011963 ABOM_011962 ABOM_011962 ABOM_011697 ABOM_011697 ABOM_011499 ABOM_011499 ABOM_011307 ABOM_011307 ABOM_011297 ABOM_011297 ABOM_011421 ABOM_011421 ABOM_011051 ABOM_011051 ABOM_010658 ABOM_010658 ABOM_010866 ABOM_010866 ABOM_011052 ABOM_011052 ABOM_010124 ABOM_010124 ABOM_010138 ABOM_010138 ABOM_009769 ABOM_009769 ABOM_009787 ABOM_009787 ABOM_010688 ABOM_010688 ABOM_010259 ABOM_010259 ABOM_010370 ABOM_010370 ABOM_010258 ABOM_010258 ABOM_008909 ABOM_008909 ABOM_009677 ABOM_009677 ABOM_009704 ABOM_009704 ABOM_009089 ABOM_009089 ABOM_008287 ABOM_008287 TIF6 TIF6 ABOM_007489 ABOM_007489 ABOM_007499 ABOM_007499 ABOM_008509 ABOM_008509 ABOM_008115 ABOM_008115 ABOM_007500 ABOM_007500 ABOM_007835 ABOM_007835 ABOM_007183 ABOM_007183 ABOM_008566 ABOM_008566 ABOM_008522 ABOM_008522 ABOM_006888 ABOM_006888 ERB1 ERB1 ABOM_007176 ABOM_007176 ABOM_008804 ABOM_008804 ABOM_007328 ABOM_007328 ABOM_007576 ABOM_007576 ABOM_007201 ABOM_007201 ABOM_006956 ABOM_006956 ABOM_006570 ABOM_006570 ABOM_006590 ABOM_006590 ABOM_006181 ABOM_006181 ABOM_006101 ABOM_006101 ABOM_007085 ABOM_007085 NAT10 NAT10 ABOM_005879 ABOM_005879 ABOM_005415 ABOM_005415 ABOM_005365 ABOM_005365 ABOM_005414 ABOM_005414 ABOM_005373 ABOM_005373 ABOM_006355 ABOM_006355 ABOM_005537 ABOM_005537 ABOM_005462 ABOM_005462 ABOM_005201 ABOM_005201 ABOM_006272 ABOM_006272 ABOM_005170 ABOM_005170 ABOM_005520 ABOM_005520 ABOM_005342 ABOM_005342 ABOM_005344 ABOM_005344 ABOM_003730 ABOM_003730 NOP7 NOP7 YTM1 YTM1 ABOM_005161 ABOM_005161 ABOM_003815 ABOM_003815 ABOM_003733 ABOM_003733 ABOM_004226 ABOM_004226 ABOM_004214 ABOM_004214 ABOM_004161 ABOM_004161 ABOM_002395 ABOM_002395 ABOM_003049 ABOM_003049 ABOM_002269 ABOM_002269 ABOM_004093 ABOM_004093 ABOM_001392 ABOM_001392 ABOM_001199 ABOM_001199 ABOM_000850 ABOM_000850 ABOM_001000 ABOM_001000 ABOM_001330 ABOM_001330 ABOM_001171 ABOM_001171 ABOM_000456 ABOM_000456 ABOM_000637 ABOM_000637 ABOM_000686 ABOM_000686 ABOM_000318 ABOM_000318
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (806 aa)
ABOM_012062ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family. (498 aa)
ABOM_012244WD domain protein. (931 aa)
ABOM_011963Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (687 aa)
ABOM_01196260S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
ABOM_011697HMG box protein. (329 aa)
ABOM_011499rRNA methyltransferase NOP1. (317 aa)
ABOM_011307Nucleolar protein nop5. (578 aa)
ABOM_011297RNA helicase. (638 aa)
ABOM_011421Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (560 aa)
ABOM_011051Uncharacterized protein. (391 aa)
ABOM_010658Small nucleolar ribonucleoprotein complex subunit Utp15. (541 aa)
ABOM_010866Ribosomal protein S5; Belongs to the universal ribosomal protein uS5 family. (298 aa)
ABOM_011052Cell morphogenesis protein Las1. (394 aa)
ABOM_010124KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (362 aa)
ABOM_010138Nucleolar GTP-binding protein 1. (658 aa)
ABOM_009769rRNA processing protein Bystin. (496 aa)
ABOM_009787SnoRNA binding protein. (1015 aa)
ABOM_010688Putative rRNA maturation protein (Nop14). (885 aa)
ABOM_010259U3 small nucleolar RNA-associated protein 7. (535 aa)
ABOM_010370rRNA biogenesis protein RRP5. (1832 aa)
ABOM_010258Pre-rRNA processing protein Tsr1. (794 aa)
ABOM_008909Putative rRNA processing protein (Ebp2). (374 aa)
ABOM_009677Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (355 aa)
ABOM_009704U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (697 aa)
ABOM_00908940S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (201 aa)
ABOM_008287RNA processing factor 1. (431 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
ABOM_007489Small nucleolar ribonucleoprotein complex subunit (SOF1). (429 aa)
ABOM_007499Ribosome biogenesis protein Ssf2. (448 aa)
ABOM_008509Putative pre-rRNA processing protein Mrd1. (833 aa)
ABOM_008115RRP7 superfamily domain-containing protein. (310 aa)
ABOM_007500ATP-dependent rRNA helicase RRP3; Belongs to the DEAD box helicase family. (472 aa)
ABOM_007835Serine/threonine-protein kinase rio2. (403 aa)
ABOM_007183rRNA processing protein RRP15. (301 aa)
ABOM_008566Ribosome biogenesis protein NSA2. (263 aa)
ABOM_008522Putative small nucleolar ribonucleoprotein complex subunit. (952 aa)
ABOM_006888AAA family ATPase/60S ribosome export protein Rix7. (741 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (784 aa)
ABOM_00717620S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (443 aa)
ABOM_008804ATP-dependent RNA helicase drs1. (1402 aa)
ABOM_007328Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (302 aa)
ABOM_007576U3 small nucleolar ribonucleoprotein Lcp5. (384 aa)
ABOM_007201Sas10/Utp3 family protein. (648 aa)
ABOM_006956Low-temperature viability protein ltv1. (486 aa)
ABOM_006570Protein phosphatase; Belongs to the universal ribosomal protein uS3 family. (266 aa)
ABOM_006590Ribosome biogenesis protein Kri1. (606 aa)
ABOM_006181Periodic tryptophan protein 2. (900 aa)
ABOM_006101Ribosome biogenesis protein BMS1. (1171 aa)
ABOM_007085Putative U3 small nucleolar ribonucleoprotein subunit (Imp3). (188 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1069 aa)
ABOM_005879Putative cellular morphogenesis protein (Bud22). (441 aa)
ABOM_005415F-box domain protein. (357 aa)
ABOM_005365Small nucleolar ribonucleoprotein complex subunit Dip2. (956 aa)
ABOM_005414Ribosome biogenesis protein BRX1. (364 aa)
ABOM_005373rRNA processing protein. (313 aa)
ABOM_006355Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4877 aa)
ABOM_005537rRNA processing protein Utp6. (395 aa)
ABOM_005462HAD_SAK_1 domain-containing protein. (578 aa)
ABOM_005201RNA binding protein Rnp24. (374 aa)
ABOM_006272Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
ABOM_005170U3 small nucleolar RNA-associated protein 22. (1110 aa)
ABOM_005520Nucleolar protein 56. (522 aa)
ABOM_005342Small nucleolar ribonucleoprotein complex subunit. (611 aa)
ABOM_005344Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
ABOM_003730Putative small nucleolar ribonucleoprotein complex subunit. (980 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (682 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (1295 aa)
ABOM_005161Putative ribosome assembly protein Noc2. (779 aa)
ABOM_003815Uncharacterized protein. (240 aa)
ABOM_003733rRNA processing protein RRP9. (621 aa)
ABOM_004226Protein PUF6. (693 aa)
ABOM_004214GTP-binding protein. (545 aa)
ABOM_004161Ribosomal RNA processing protein. (313 aa)
ABOM_002395U3 small nucleolar ribonucleoprotein IMP4. (299 aa)
ABOM_003049rRNA-processing protein fcf1. (191 aa)
ABOM_002269Putative small nucleolar ribonucleoprotein complex subunit Utp14. (967 aa)
ABOM_004093RNA helicase. (797 aa)
ABOM_001392U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (287 aa)
ABOM_001199DEAH-box RNA helicase (Dhr1). (1147 aa)
ABOM_000850WD repeat protein. (720 aa)
ABOM_001000HEAT repeat protein (DRIM). (2614 aa)
ABOM_001330Putative C2H2 finger domain protein. (111 aa)
ABOM_001171Protein MAK16; Belongs to the MAK16 family. (326 aa)
ABOM_000456Ribosome biogenesis protein Noc4. (550 aa)
ABOM_000637Uncharacterized protein. (396 aa)
ABOM_000686rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (411 aa)
ABOM_000318RNA-3'-phosphate cyclase family protein. (402 aa)
Your Current Organism:
Aspergillus bombycis
NCBI taxonomy Id: 109264
Other names: A. bombycis, Aspergillus bombycis S.W. Peterson, Yoko Ito, B.W. Horn & T. Goto, 2001, CBS 117187, NRRL 26010
Server load: low (14%) [HD]