(56 nodes) Lipoprotein metabolic process network (Aspergillus bombycis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	ABOM_012058	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (716 aa)
	ABOM_011754	GPI ethanolamine phosphate transferase 1. (1022 aa)
	ABOM_008225	SVP1-like protein 2. (377 aa)
	ABOM_008827	N-acetylglucosaminyl transferase component Gpi1. (720 aa)
	ABOM_008816	GPI-anchored wall transfer protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (500 aa)
	ABOM_011588	Autophagy-related protein 3. (356 aa)
	ABOM_011591	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (467 aa)
	ABOM_011448	Uncharacterized protein. (864 aa)
	ABOM_011391	Mannosyltransferase. (793 aa)
	ABOM_011180	Uncharacterized protein. (558 aa)
	ABOM_006862	GPI transamidase component PIG-S. (568 aa)
	ABOM_006710	Palmitoyl-protein thioesterase. (327 aa)
	ABOM_006489	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (116 aa)
	ABOM_010603	Phosphatidylinositol glycan. (953 aa)
	ABOM_010882	GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity. (392 aa)
	ABOM_011074	N-acetylglucosaminyl-phosphatidylinositol deacetylase. (305 aa)
	ABOM_010471	Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family. (92 aa)
	ABOM_008746	GPI ethanolamine phosphate transferase 2. (687 aa)
	ABOM_010164	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (737 aa)
	ABOM_009037	Glycosyltransferase. (612 aa)
	ABOM_005847	GPI transamidase component Gpi16. (591 aa)
	ABOM_005381	Uncharacterized protein. (263 aa)
	ABOM_005536	Putative integral plasma membrane protein. (949 aa)
	ABOM_005497	Putative glycan biosynthesis protein (PigL). (304 aa)
	ABOM_006038	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (530 aa)
	ABOM_004882	Phospholipase/carboxylesterase. (216 aa)
	ABOM_005244	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (612 aa)
	ABOM_004558	GPI-GlcNAc transferase subunit P. (333 aa)
	ABOM_005073	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (403 aa)
	ABOM_004961	Uncharacterized protein. (337 aa)
	ABOM_004836	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (248 aa)
	PFA4	Palmitoyltransferase PFA4; Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function; Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily. (432 aa)
	ABOM_000825	Glycerol:H+ symporter (Gup1); Belongs to the membrane-bound acyltransferase family. (605 aa)
	ABOM_001153	Uncharacterized protein. (411 aa)
	ABOM_008948	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (452 aa)
	ABOM_009122	Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (245 aa)
	ABOM_003664	GPI transamidase component GAB1. (423 aa)
	ABOM_003266	Phosphatidylinositol:UDP-GlcNAc transferase PIG-C. (496 aa)
	ABOM_002748	Glycan biosynthesis protein (PigL). (303 aa)
	ABOM_003440	Uncharacterized protein. (178 aa)
	ABOM_002052	GPI-anchored wall transfer protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (470 aa)
	ABOM_002053	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. (172 aa)
	ABOM_004048	Glycosyl transferase. (481 aa)
	ABOM_004038	Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit. (478 aa)
	ABOM_001315	GPI transamidase component (GAA1). (636 aa)
	ABOM_001311	Abhydrolase_2 domain-containing protein. (362 aa)
	ABOM_001103	Protein PBN1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14. (540 aa)
	ABOM_001430	GPI-anchor biosynthesis protein (Pig-F). (229 aa)
	ABOM_001195	Phosphoethanolamine N-methyltransferase. (1079 aa)
	ABOM_003676	Glycylpeptide N-tetradecanoyltransferase; Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins; Belongs to the NMT family. (497 aa)
	ABOM_009609	Uncharacterized protein. (1569 aa)
	ABOM_008301	Mannosyltransferase. (441 aa)
	ABOM_009036	DNA damage response protein RcaA. (708 aa)
	ABOM_008307	Phospholipase/Carboxylesterase superfamily. (267 aa)
	ABOM_007502	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (333 aa)
	ABOM_008247	Acyl-protein thioesterase 1. (244 aa)

Your Current Organism:

Aspergillus bombycis

NCBI taxonomy Id: 109264
Other names: A. bombycis, Aspergillus bombycis S.W. Peterson, Yoko Ito, B.W. Horn & T. Goto, 2001, CBS 117187, NRRL 26010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABOM_000825	ABOM_007502	A0A1F8AF88	A0A1F7ZTV9	Glycerol:H+ symporter (Gup1); Belongs to the membrane-bound acyltransferase family.	Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family.	0.417
ABOM_001153	ABOM_002748	A0A1F8AEZ5	A0A1F8A8F3	Uncharacterized protein.	Glycan biosynthesis protein (PigL).	0.645
ABOM_001153	ABOM_003266	A0A1F8AEZ5	A0A1F8A7Y6	Uncharacterized protein.	Phosphatidylinositol:UDP-GlcNAc transferase PIG-C.	0.850
ABOM_001153	ABOM_004038	A0A1F8AEZ5	A0A1F8ACS0	Uncharacterized protein.	Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit.	0.833
ABOM_001153	ABOM_004048	A0A1F8AEZ5	A0A1F8ACA9	Uncharacterized protein.	Glycosyl transferase.	0.833
ABOM_001153	ABOM_005497	A0A1F8AEZ5	A0A1F8A212	Uncharacterized protein.	Putative glycan biosynthesis protein (PigL).	0.645
ABOM_001153	ABOM_005847	A0A1F8AEZ5	A0A1F8A1N7	Uncharacterized protein.	GPI transamidase component Gpi16.	0.413
ABOM_001153	ABOM_006489	A0A1F8AEZ5	A0A1F8A1F5	Uncharacterized protein.	Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.	0.819
ABOM_001153	ABOM_008827	A0A1F8AEZ5	A0A1F7ZXA5	Uncharacterized protein.	N-acetylglucosaminyl transferase component Gpi1.	0.819
ABOM_001153	ABOM_011074	A0A1F8AEZ5	A0A1F7ZM82	Uncharacterized protein.	N-acetylglucosaminyl-phosphatidylinositol deacetylase.	0.645
ABOM_001153	ABOM_011391	A0A1F8AEZ5	A0A1F7ZKX9	Uncharacterized protein.	Mannosyltransferase.	0.426
ABOM_001195	ABOM_001315	A0A1F8AEX7	A0A1F8AEC6	Phosphoethanolamine N-methyltransferase.	GPI transamidase component (GAA1).	0.936
ABOM_001195	ABOM_001430	A0A1F8AEX7	A0A1F8AES1	Phosphoethanolamine N-methyltransferase.	GPI-anchor biosynthesis protein (Pig-F).	0.920
ABOM_001195	ABOM_002053	A0A1F8AEX7	A0A1F8AAN4	Phosphoethanolamine N-methyltransferase.	GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.	0.575
ABOM_001195	ABOM_003664	A0A1F8AEX7	A0A1F8A705	Phosphoethanolamine N-methyltransferase.	GPI transamidase component GAB1.	0.939
ABOM_001195	ABOM_004038	A0A1F8AEX7	A0A1F8ACS0	Phosphoethanolamine N-methyltransferase.	Phosphatidylinositol N-acetylglucosaminyltransferase gpi3 subunit.	0.512
ABOM_001195	ABOM_004048	A0A1F8AEX7	A0A1F8ACA9	Phosphoethanolamine N-methyltransferase.	Glycosyl transferase.	0.432
ABOM_001195	ABOM_004558	A0A1F8AEX7	A0A1F8A453	Phosphoethanolamine N-methyltransferase.	GPI-GlcNAc transferase subunit P.	0.401
ABOM_001195	ABOM_005073	A0A1F8AEX7	A0A1F8A4V4	Phosphoethanolamine N-methyltransferase.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.950
ABOM_001195	ABOM_005847	A0A1F8AEX7	A0A1F8A1N7	Phosphoethanolamine N-methyltransferase.	GPI transamidase component Gpi16.	0.929