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ABOM_010124 ABOM_010124 SPB1 SPB1 ABOM_009704 ABOM_009704 TIF6 TIF6 ABOM_002978 ABOM_002978 ABOM_004097 ABOM_004097 ABOM_001226 ABOM_001226 ABOM_008797 ABOM_008797 ERB1 ERB1 YTM1 YTM1 ABOM_006272 ABOM_006272 ABOM_006870 ABOM_006870 ABOM_005170 ABOM_005170 ABOM_005432 ABOM_005432 NOP7 NOP7 ABOM_011963 ABOM_011963 ABOM_011962 ABOM_011962 ABOM_011667 ABOM_011667
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABOM_010124KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (362 aa)
SPB1AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (806 aa)
ABOM_009704U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (697 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
ABOM_002978Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (247 aa)
ABOM_004097ATP-dependent RNA helicase DBP10. (926 aa)
ABOM_001226rRNA biogenesis protein rrp36. (349 aa)
ABOM_008797Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (753 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (784 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (1295 aa)
ABOM_006272Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
ABOM_006870U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (726 aa)
ABOM_005170U3 small nucleolar RNA-associated protein 22. (1110 aa)
ABOM_005432WD repeat-containing protein. (505 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (682 aa)
ABOM_011963Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (687 aa)
ABOM_01196260S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
ABOM_011667rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (114 aa)
Your Current Organism:
Aspergillus bombycis
NCBI taxonomy Id: 109264
Other names: A. bombycis, Aspergillus bombycis S.W. Peterson, Yoko Ito, B.W. Horn & T. Goto, 2001, CBS 117187, NRRL 26010
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