(64 nodes) Autophagy network (Aspergillus bombycis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABOM_004157	Non-specific serine/threonine protein kinase. (1065 aa)
	ABOM_000440	Peroxisomal targeting receptor pex5. (658 aa)
	ABOM_000435	Autophagy protein Apg6. (525 aa)
	ABOM_000972	Uncharacterized protein. (344 aa)
	ABOM_000851	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily. (973 aa)
	ABOM_001217	Snf1 kinase complex beta-subunit Gal83. (474 aa)
	ABOM_001352	Magnesium dependent phosphatase. (219 aa)
	ABOM_004103	Uncharacterized protein. (1612 aa)
	ABOM_004124	Import receptor subunit tom-20. (170 aa)
	ABOM_002962	UV radiation resistance protein (UVRAG). (616 aa)
	ABOM_002992	Ubiquitin hydrolase; Belongs to the peptidase C19 family. (655 aa)
	ABOM_003044	Vacuolar protein sorting protein 24. (229 aa)
	ABOM_002968	Transmembrane GTPase Fzo1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (933 aa)
	ABOM_002969	DOA4-independent degradation protein 4. (223 aa)
	ABOM_003484	Ubiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (149 aa)
	ABOM_002183	Uncharacterized protein. (182 aa)
	ABOM_012214	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (679 aa)
	ABOM_012215	Putative autophagy protein Apg9. (199 aa)
	ABOM_012058	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...] (716 aa)
	ABOM_011022	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. (403 aa)
	ABOM_011588	Autophagy-related protein 3. (356 aa)
	ABOM_011415	Serine/threonine protein kinase (Pdd7p). (969 aa)
	ABOM_010821	SNF7 family protein. (451 aa)
	ABOM_011064	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2880 aa)
	ABOM_010753	Autophagy-related protein Atg10. (261 aa)
	ABOM_010015	Casein kinase; Belongs to the protein kinase superfamily. (332 aa)
	ABOM_010390	AMPK1_CBM domain-containing protein. (491 aa)
	ABOM_010067	Ubiquitin-40S ribosomal protein S31 fusion protein. (217 aa)
	ABOM_008895	Autophagy protein 16. (205 aa)
	ABOM_008760	Import receptor subunit tom-40. (355 aa)
	ABOM_008753	TOM complex component Tom7. (49 aa)
	ABOM_009233	Serine/threonine protein kinase. (1277 aa)
	ABOM_009395	Autophagy-related protein. (118 aa)
	ABOM_009678	BZIP domain-containing protein. (282 aa)
	ABOM_009677	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (355 aa)
	ABOM_009149	Autophagy-related protein 11. (1325 aa)
	ABOM_009245	Uncharacterized protein. (120 aa)
	ABOM_009137	Ubiquitin carboxyl-terminal hydrolase. (644 aa)
	ABOM_008959	Cell division control protein Cdc31. (257 aa)
	ABOM_007536	Protein sds23; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (525 aa)
	ABOM_007510	Vacuolar-sorting protein SNF7. (223 aa)
	ABOM_008225	SVP1-like protein 2. (377 aa)
	MDM34	Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (566 aa)
	ABOM_007841	Autophagy-related protein 18. (428 aa)
	ABOM_008227	Dynein light intermediate chain. (570 aa)
	ABOM_006889	SNF7 family protein. (207 aa)
	ABOM_007045	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation. (322 aa)
	ABOM_007328	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (302 aa)
	ABOM_006979	DUF1649 domain protein. (201 aa)
	ABOM_007281	MYND-type domain-containing protein. (347 aa)
	ABOM_006569	Protein phosphatase. (753 aa)
	ABOM_007257	Mitochondrial import receptor subunit tom22. (153 aa)
	ABOM_005831	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy. (176 aa)
	ABOM_005853	Uncharacterized protein. (162 aa)
	ABOM_005506	Prenylcysteine lyase. (506 aa)
	ABOM_004829	Phosphatidylinositol 3-kinase VPS34. (902 aa)
	ABOM_005199	ZZ type zinc finger domain protein. (810 aa)
	ABOM_004569	Zn(II)2Cys6 transcription factor. (736 aa)
	ABOM_004434	Uncharacterized protein. (223 aa)
	ABOM_003762	Non-specific serine/threonine protein kinase. (798 aa)
	ABOM_003769	Import receptor subunit tom-70. (611 aa)
	ABOM_002655	CIA30 family protein. (230 aa)
	ABOM_003323	Uncharacterized protein. (119 aa)
	ABOM_003278	DJ-1_PfpI domain-containing protein. (218 aa)

Your Current Organism:

Aspergillus bombycis

NCBI taxonomy Id: 109264
Other names: A. bombycis, Aspergillus bombycis S.W. Peterson, Yoko Ito, B.W. Horn & T. Goto, 2001, CBS 117187, NRRL 26010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABOM_000435	ABOM_000851	A0A1F8AG01	A0A1F8AFB7	Autophagy protein Apg6.	Autophagy-related protein 13; Belongs to the ATG13 family. Fungi subfamily.	0.701
ABOM_000435	ABOM_001217	A0A1F8AG01	A0A1F8AEZ9	Autophagy protein Apg6.	Snf1 kinase complex beta-subunit Gal83.	0.687
ABOM_000435	ABOM_002962	A0A1F8AG01	A0A1F8ABT3	Autophagy protein Apg6.	UV radiation resistance protein (UVRAG).	0.973
ABOM_000435	ABOM_003323	A0A1F8AG01	A0A1F8A7R4	Autophagy protein Apg6.	Uncharacterized protein.	0.771
ABOM_000435	ABOM_003762	A0A1F8AG01	A0A1F8A6M7	Autophagy protein Apg6.	Non-specific serine/threonine protein kinase.	0.624
ABOM_000435	ABOM_004103	A0A1F8AG01	A0A1F8AD78	Autophagy protein Apg6.	Uncharacterized protein.	0.975
ABOM_000435	ABOM_004157	A0A1F8AG01	A0A1F8A855	Autophagy protein Apg6.	Non-specific serine/threonine protein kinase.	0.624
ABOM_000435	ABOM_004434	A0A1F8AG01	A0A1F8A5I4	Autophagy protein Apg6.	Uncharacterized protein.	0.624
ABOM_000435	ABOM_004829	A0A1F8AG01	A0A1F8A3T8	Autophagy protein Apg6.	Phosphatidylinositol 3-kinase VPS34.	0.992
ABOM_000435	ABOM_005199	A0A1F8AG01	A0A1F8A3X3	Autophagy protein Apg6.	ZZ type zinc finger domain protein.	0.659
ABOM_000435	ABOM_005831	A0A1F8AG01	A0A1F8A0D2	Autophagy protein Apg6.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.	0.858
ABOM_000435	ABOM_006979	A0A1F8AG01	A0A1F7ZYD0	Autophagy protein Apg6.	DUF1649 domain protein.	0.816
ABOM_000435	ABOM_007045	A0A1F8AG01	A0A1F7ZXC5	Autophagy protein Apg6.	Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.	0.791
ABOM_000435	ABOM_007536	A0A1F8AG01	A0A1F7ZTV4	Autophagy protein Apg6.	Protein sds23; Involved in DNA replication and cell separation. Belongs to the SDS23 family.	0.611
ABOM_000435	ABOM_007841	A0A1F8AG01	A0A1F7ZVJ3	Autophagy protein Apg6.	Autophagy-related protein 18.	0.853
ABOM_000435	ABOM_008225	A0A1F8AG01	A0A1F7ZUM5	Autophagy protein Apg6.	SVP1-like protein 2.	0.527
ABOM_000435	ABOM_008895	A0A1F8AG01	A0A1F7ZQ09	Autophagy protein Apg6.	Autophagy protein 16.	0.771
ABOM_000435	ABOM_009149	A0A1F8AG01	A0A1F7ZRQ3	Autophagy protein Apg6.	Autophagy-related protein 11.	0.675
ABOM_000435	ABOM_009233	A0A1F8AG01	A0A1F7ZQQ7	Autophagy protein Apg6.	Serine/threonine protein kinase.	0.624
ABOM_000435	ABOM_009245	A0A1F8AG01	A0A1F7ZRQ4	Autophagy protein Apg6.	Uncharacterized protein.	0.771