(32 nodes) Nervous system development network (Aspergillus bombycis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABOM_002214	Amidohydro-rel domain-containing protein. (444 aa)
	ABOM_003359	Cofilin; Belongs to the actin-binding proteins ADF family. (161 aa)
	ABOM_003493	Actin associated protein Wsp1. (498 aa)
	ABOM_002490	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
	ABOM_011531	Cofilin; Belongs to the actin-binding proteins ADF family. (154 aa)
	ABOM_011846	Ricin B-type lectin domain-containing protein. (111 aa)
	ABOM_011256	C6 finger domain protein. (860 aa)
	ABOM_010450	Homeobox transcription factor. (579 aa)
	ABOM_011041	Ricin B-type lectin domain-containing protein. (150 aa)
	ABOM_010544	Fungal_trans domain-containing protein. (603 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (815 aa)
	ABOM_006542	MAP kinase kinase (Mkk2); Belongs to the protein kinase superfamily. (471 aa)
	ABOM_007469	Allantoinase. (504 aa)
	ABOM_006225	Endopolygalacturonase D. (492 aa)
	ABOM_005266	Cell division control protein 42. (199 aa)
	ABOM_005696	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (145 aa)
	ABOM_005207	MAP kinase kinase Ste7. (522 aa)
	ABOM_002767	Uncharacterized protein. (150 aa)
	ABOM_004661	Zn(II)2Cys6 transcription factor. (705 aa)
	ABOM_004852	Uncharacterized protein. (322 aa)
	ABOM_005143	Protein kinase wis1. (637 aa)
	ABOM_003713	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1670 aa)
	ABOM_010897	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (716 aa)
	ABOM_002276	Uncharacterized protein. (96 aa)
	ABOM_001938	Rad60-SLD_2 domain-containing protein. (260 aa)
	ABOM_000797	Uncharacterized protein. (336 aa)
	ABOM_000117	Zn(2)-C6 fungal-type domain-containing protein. (487 aa)
	ABOM_010248	Allergenic cerato-platanin Asp F13. (157 aa)
	ABOM_009610	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (440 aa)
	ABOM_009194	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (244 aa)
	ABOM_011990	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (941 aa)
	ABOM_012003	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (747 aa)

Your Current Organism:

Aspergillus bombycis

NCBI taxonomy Id: 109264
Other names: A. bombycis, Aspergillus bombycis S.W. Peterson, Yoko Ito, B.W. Horn & T. Goto, 2001, CBS 117187, NRRL 26010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABOM_000117	ABOM_011990	A0A1F8AHE5	A0A1F7ZIS8	Zn(2)-C6 fungal-type domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.490
ABOM_001938	ABOM_002490	A0A1F8AD63	A0A1F8AA03	Rad60-SLD_2 domain-containing protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.965
ABOM_001938	ABOM_003713	A0A1F8AD63	A0A1F8A5R9	Rad60-SLD_2 domain-containing protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.966
ABOM_001938	ABOM_005266	A0A1F8AD63	A0A1F8A2L8	Rad60-SLD_2 domain-containing protein.	Cell division control protein 42.	0.484
ABOM_001938	ABOM_009194	A0A1F8AD63	A0A1F7ZUX5	Rad60-SLD_2 domain-containing protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.886
ABOM_001938	ABOM_009610	A0A1F8AD63	A0A1F7ZT02	Rad60-SLD_2 domain-containing protein.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.969
ABOM_001938	ABOM_011990	A0A1F8AD63	A0A1F7ZIS8	Rad60-SLD_2 domain-containing protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.934
ABOM_002490	ABOM_001938	A0A1F8AA03	A0A1F8AD63	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Rad60-SLD_2 domain-containing protein.	0.965
ABOM_002490	ABOM_003713	A0A1F8AA03	A0A1F8A5R9	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.906
ABOM_002490	ABOM_009194	A0A1F8AA03	A0A1F7ZUX5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.908
ABOM_002490	ABOM_009610	A0A1F8AA03	A0A1F7ZT02	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.999
ABOM_002490	ABOM_010897	A0A1F8AA03	A0A1F7ZNY5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.988
ABOM_002490	ABOM_011990	A0A1F8AA03	A0A1F7ZIS8	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.996
ABOM_002490	ABOM_012003	A0A1F8AA03	A0A1F7ZIZ5	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.965
ABOM_003359	ABOM_003493	A0A1F8A9N3	A0A1F8A9R6	Cofilin; Belongs to the actin-binding proteins ADF family.	Actin associated protein Wsp1.	0.433
ABOM_003493	ABOM_003359	A0A1F8A9R6	A0A1F8A9N3	Actin associated protein Wsp1.	Cofilin; Belongs to the actin-binding proteins ADF family.	0.433
ABOM_003493	ABOM_003713	A0A1F8A9R6	A0A1F8A5R9	Actin associated protein Wsp1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.862
ABOM_003493	ABOM_005266	A0A1F8A9R6	A0A1F8A2L8	Actin associated protein Wsp1.	Cell division control protein 42.	0.958
ABOM_003493	ABOM_005696	A0A1F8A9R6	A0A1F8A2Z7	Actin associated protein Wsp1.	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.	0.433
ABOM_003493	ABOM_009194	A0A1F8A9R6	A0A1F7ZUX5	Actin associated protein Wsp1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.762