(11 nodes) Mixed, incl. PTW/PP1 phosphatase complex, and CPI-17 superfamily network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC109509254	Protein kinase domain-containing protein. (178 aa)
	rock1	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1333 aa)
	LOC109531368	Uncharacterized protein. (193 aa)
	LOC109507600	Protein phosphatase 1 regulatory subunit. (905 aa)
	LOC109517394	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	LOC109531589	Myosin light chain, phosphorylatable, fast skeletal muscle a. (145 aa)
	LOC109507997	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa. (163 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	LOC109514994	PRKG1_interact domain-containing protein. (195 aa)
	ppp1r12a	Protein phosphatase 1 regulatory subunit. (1077 aa)
	LOC109510790	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab. (152 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC109507600	LOC109507997	ENSHCOP00000016761	ENSHCOP00000021520	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	0.548
LOC109507600	LOC109510790	ENSHCOP00000016761	ENSHCOP00000027707	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.	0.445
LOC109507600	LOC109517394	ENSHCOP00000016761	ENSHCOP00000016906	Protein phosphatase 1 regulatory subunit.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.814
LOC109507600	PPP1CB	ENSHCOP00000016761	ENSHCOP00000022232	Protein phosphatase 1 regulatory subunit.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.814
LOC109507997	LOC109507600	ENSHCOP00000021520	ENSHCOP00000016761	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	Protein phosphatase 1 regulatory subunit.	0.548
LOC109507997	LOC109510790	ENSHCOP00000021520	ENSHCOP00000027707	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.	0.902
LOC109507997	LOC109514994	ENSHCOP00000021520	ENSHCOP00000023422	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	PRKG1_interact domain-containing protein.	0.942
LOC109507997	LOC109517394	ENSHCOP00000021520	ENSHCOP00000016906	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.953
LOC109507997	PPP1CB	ENSHCOP00000021520	ENSHCOP00000022232	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.953
LOC109507997	ppp1r12a	ENSHCOP00000021520	ENSHCOP00000026608	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	Protein phosphatase 1 regulatory subunit.	0.952
LOC109509254	LOC109514994	ENSHCOP00000006802	ENSHCOP00000023422	Protein kinase domain-containing protein.	PRKG1_interact domain-containing protein.	0.927
LOC109509254	LOC109517394	ENSHCOP00000006802	ENSHCOP00000016906	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.913
LOC109509254	LOC109531368	ENSHCOP00000006802	ENSHCOP00000015776	Protein kinase domain-containing protein.	Uncharacterized protein.	0.956
LOC109509254	LOC109531589	ENSHCOP00000006802	ENSHCOP00000018528	Protein kinase domain-containing protein.	Myosin light chain, phosphorylatable, fast skeletal muscle a.	0.920
LOC109509254	PPP1CB	ENSHCOP00000006802	ENSHCOP00000022232	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.	0.913
LOC109509254	ppp1r12a	ENSHCOP00000006802	ENSHCOP00000026608	Protein kinase domain-containing protein.	Protein phosphatase 1 regulatory subunit.	0.927
LOC109509254	rock1	ENSHCOP00000006802	ENSHCOP00000014302	Protein kinase domain-containing protein.	Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.900
LOC109510790	LOC109507600	ENSHCOP00000027707	ENSHCOP00000016761	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.	Protein phosphatase 1 regulatory subunit.	0.445
LOC109510790	LOC109507997	ENSHCOP00000027707	ENSHCOP00000021520	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.	Protein phosphatase 1, regulatory (inhibitor) subunit 14Aa.	0.902
LOC109510790	LOC109514994	ENSHCOP00000027707	ENSHCOP00000023422	Protein phosphatase 1, regulatory (inhibitor) subunit 14Ab.	PRKG1_interact domain-containing protein.	0.942