(35 nodes) Mixed, incl. Negative regulation of sister chromatid segregation, and Chromosome passenger complex network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	melk	Non-specific serine/threonine protein kinase. (679 aa)
	Cenpe	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (150 aa)
	mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast). (202 aa)
	prc1	Protein regulator of cytokinesis 1b. (584 aa)
	ENSHCOP00000006919	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (444 aa)
	kif14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1237 aa)
	ttk	Ttk protein kinase. (740 aa)
	pbk	PDZ binding kinase. (321 aa)
	cdc20	Cell division cycle 20 homolog. (503 aa)
	ENSHCOP00000010827	CENP-F_N domain-containing protein. (70 aa)
	dlgap5	Discs, large (Drosophila) homolog-associated protein 5. (768 aa)
	tpx2	TPX2 microtubule nucleation factor. (595 aa)
	LOC109522581	Marker of proliferation Ki-67. (2064 aa)
	cdkn3	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (209 aa)
	cdca3	Si:ch211-69g19.2. (394 aa)
	kif11	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (841 aa)
	nusap1	Uncharacterized protein. (418 aa)
	LOC109507509	Protein regulator of cytokinesis 1a. (598 aa)
	kntc1	Kinetochore associated 1. (1534 aa)
	incenp	Uncharacterized protein. (731 aa)
	LOC109510652	Aurora kinase A; Belongs to the protein kinase superfamily. (456 aa)
	cep55	Centrosomal protein 55 like. (494 aa)
	cdca8	Cell division cycle associated 8. (276 aa)
	LOC109515948	Aurora kinase B; Belongs to the protein kinase superfamily. (330 aa)
	aspm	Abnormal spindle microtubule assembly. (2957 aa)
	mad1l1	Mitotic arrest deficient 1 like 1. (720 aa)
	LOC109516568	Baculoviral IAP repeat containing 5a. (137 aa)
	zwilch	Zwilch kinetochore protein. (581 aa)
	pttg1	Uncharacterized protein. (173 aa)
	kif22	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (632 aa)
	bub1b	BUB1 mitotic checkpoint serine/threonine kinase Bb. (429 aa)
	foxm1	Forkhead box M1. (642 aa)
	bub3	BUB3 mitotic checkpoint protein. (342 aa)
	kif4a	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1190 aa)
	espl1	Extra spindle pole bodies like 1, separase. (1564 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cenpe	ENSHCOP00000006919	ENSHCOP00000001931	ENSHCOP00000006919	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.972
Cenpe	ENSHCOP00000010827	ENSHCOP00000001931	ENSHCOP00000010827	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	CENP-F_N domain-containing protein.	0.972
Cenpe	LOC109507509	ENSHCOP00000001931	ENSHCOP00000015592	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Protein regulator of cytokinesis 1a.	0.844
Cenpe	LOC109510652	ENSHCOP00000001931	ENSHCOP00000017419	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.571
Cenpe	LOC109515948	ENSHCOP00000001931	ENSHCOP00000020901	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.571
Cenpe	LOC109516568	ENSHCOP00000001931	ENSHCOP00000024485	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Baculoviral IAP repeat containing 5a.	0.867
Cenpe	LOC109522581	ENSHCOP00000001931	ENSHCOP00000013235	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Marker of proliferation Ki-67.	0.882
Cenpe	aspm	ENSHCOP00000001931	ENSHCOP00000022051	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Abnormal spindle microtubule assembly.	0.922
Cenpe	bub1b	ENSHCOP00000001931	ENSHCOP00000026701	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BUB1 mitotic checkpoint serine/threonine kinase Bb.	0.983
Cenpe	bub3	ENSHCOP00000001931	ENSHCOP00000027944	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	BUB3 mitotic checkpoint protein.	0.804
Cenpe	cdc20	ENSHCOP00000001931	ENSHCOP00000010675	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cell division cycle 20 homolog.	0.915
Cenpe	cdca3	ENSHCOP00000001931	ENSHCOP00000013936	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Si:ch211-69g19.2.	0.500
Cenpe	cdca8	ENSHCOP00000001931	ENSHCOP00000018817	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cell division cycle associated 8.	0.836
Cenpe	cdkn3	ENSHCOP00000001931	ENSHCOP00000013266	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.	0.689
Cenpe	cep55	ENSHCOP00000001931	ENSHCOP00000018404	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Centrosomal protein 55 like.	0.874
Cenpe	dlgap5	ENSHCOP00000001931	ENSHCOP00000011272	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Discs, large (Drosophila) homolog-associated protein 5.	0.908
Cenpe	espl1	ENSHCOP00000001931	ENSHCOP00000028315	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Extra spindle pole bodies like 1, separase.	0.844
Cenpe	foxm1	ENSHCOP00000001931	ENSHCOP00000026744	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Forkhead box M1.	0.509
Cenpe	incenp	ENSHCOP00000001931	ENSHCOP00000016702	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.647
Cenpe	kif11	ENSHCOP00000001931	ENSHCOP00000015410	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.972