(34 nodes) Anaphase-promoting complex, and Cyclin A/B-like network (Hippocampus comes)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccnb3	Cyclin B3; Belongs to the cyclin family. (419 aa)
	Anapc1	Uncharacterized protein. (149 aa)
	LOC109526806	Cell division cycle 14B. (559 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	anapc2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (745 aa)
	LOC109516890	WD_REPEATS_REGION domain-containing protein. (488 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
	ccna2	Cyclin A2; Belongs to the cyclin family. (394 aa)
	ENSHCOP00000008755	Protein kinase domain-containing protein. (396 aa)
	anapc13	Anaphase promoting complex subunit 13. (74 aa)
	Anapc5	Anaphase promoting complex subunit 5. (425 aa)
	ENSHCOP00000009928	Anaphase promoting complex subunit 5. (327 aa)
	anapc10	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
	cdc16	Cell division cycle 16 homolog (S. cerevisiae). (523 aa)
	anapc11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	anapc15	Anaphase promoting complex subunit 15. (123 aa)
	ube2c	Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (189 aa)
	bicral	BRD4 interacting chromatin remodeling complex associated protein like. (698 aa)
	anapc16	Anaphase promoting complex subunit 16. (83 aa)
	FZR1	Fizzy/cell division cycle 20 related 1a. (495 aa)
	cdc23	CDC23 (cell division cycle 23, yeast, homolog). (580 aa)
	cdc26	Cell division cycle 26 homolog. (95 aa)
	cdc27	Cell division cycle 27. (803 aa)
	anapc1	Anaphase promoting complex subunit 1. (1677 aa)
	ccnb1	Cyclin B1; Belongs to the cyclin family. (396 aa)
	LOC109521384	Fizzy/cell division cycle 20 related 1b. (481 aa)
	LOC109521383	Fizzy/cell division cycle 20 related 1b. (481 aa)
	nek2	NIMA-related kinase 2. (425 aa)
	LOC109514392	Cyclin B2; Belongs to the cyclin family. (385 aa)
	anapc4	Anaphase promoting complex subunit 4. (758 aa)
	PLK1	Serine/threonine-protein kinase PLK. (588 aa)
	fam89a	Family with sequence similarity 89 member A. (177 aa)
	bicra	BRD4 interacting chromatin remodeling complex associated protein. (1764 aa)
	ube2s	Ubiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (217 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Anapc1	Anapc5	ENSHCOP00000002167	ENSHCOP00000009917	Uncharacterized protein.	Anaphase promoting complex subunit 5.	0.963
Anapc1	ENSHCOP00000008755	ENSHCOP00000002167	ENSHCOP00000008755	Uncharacterized protein.	Protein kinase domain-containing protein.	0.843
Anapc1	ENSHCOP00000009928	ENSHCOP00000002167	ENSHCOP00000009928	Uncharacterized protein.	Anaphase promoting complex subunit 5.	0.963
Anapc1	FZR1	ENSHCOP00000002167	ENSHCOP00000017421	Uncharacterized protein.	Fizzy/cell division cycle 20 related 1a.	0.956
Anapc1	LOC109514392	ENSHCOP00000002167	ENSHCOP00000020136	Uncharacterized protein.	Cyclin B2; Belongs to the cyclin family.	0.944
Anapc1	LOC109516890	ENSHCOP00000002167	ENSHCOP00000006622	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.956
Anapc1	LOC109521383	ENSHCOP00000002167	ENSHCOP00000019699	Uncharacterized protein.	Fizzy/cell division cycle 20 related 1b.	0.956
Anapc1	LOC109521384	ENSHCOP00000002167	ENSHCOP00000019683	Uncharacterized protein.	Fizzy/cell division cycle 20 related 1b.	0.956
Anapc1	LOC109526806	ENSHCOP00000002167	ENSHCOP00000002362	Uncharacterized protein.	Cell division cycle 14B.	0.920
Anapc1	PLK1	ENSHCOP00000002167	ENSHCOP00000023113	Uncharacterized protein.	Serine/threonine-protein kinase PLK.	0.643
Anapc1	anapc1	ENSHCOP00000002167	ENSHCOP00000018607	Uncharacterized protein.	Anaphase promoting complex subunit 1.	0.949
Anapc1	anapc10	ENSHCOP00000002167	ENSHCOP00000010697	Uncharacterized protein.	Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.	0.983
Anapc1	anapc11	ENSHCOP00000002167	ENSHCOP00000011194	Uncharacterized protein.	APC11 anaphase promoting complex subunit 11 homolog (yeast).	0.983
Anapc1	anapc13	ENSHCOP00000002167	ENSHCOP00000009782	Uncharacterized protein.	Anaphase promoting complex subunit 13.	0.968
Anapc1	anapc15	ENSHCOP00000002167	ENSHCOP00000011621	Uncharacterized protein.	Anaphase promoting complex subunit 15.	0.955
Anapc1	anapc16	ENSHCOP00000002167	ENSHCOP00000013072	Uncharacterized protein.	Anaphase promoting complex subunit 16.	0.969
Anapc1	anapc2	ENSHCOP00000002167	ENSHCOP00000004984	Uncharacterized protein.	Anaphase promoting complex subunit 2; Belongs to the cullin family.	0.975
Anapc1	anapc4	ENSHCOP00000002167	ENSHCOP00000021388	Uncharacterized protein.	Anaphase promoting complex subunit 4.	0.984
Anapc1	anapc7	ENSHCOP00000002167	ENSHCOP00000004309	Uncharacterized protein.	Anaphase promoting complex subunit 7.	0.964
Anapc1	bicra	ENSHCOP00000002167	ENSHCOP00000026603	Uncharacterized protein.	BRD4 interacting chromatin remodeling complex associated protein.	0.883