20 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nsmce2	SP-RING-type domain-containing protein. (224 aa)
	ercc4	Excision repair cross-complementation group 4. (900 aa)
	xrcc3	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (341 aa)
	smc6	Si:dkey-119f1.1. (1086 aa)
	rad51d	RAD51 paralog D. (337 aa)
	ENSHCOP00000008383	Uncharacterized protein. (57 aa)
	tprkb	Tp53rk binding protein; Belongs to the CGI121/TPRKB family. (175 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	ercc1	Excision repair cross-complementation group 1. (338 aa)
	rad51c	RAD51 paralog C. (355 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1285 aa)
	msh3	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (1057 aa)
	ENSHCOP00000023012	Uncharacterized protein. (1155 aa)
	rad52	RAD52 homolog, DNA repair protein. (392 aa)
	ENSHCOP00000023803	Uncharacterized protein. (1781 aa)
	ENSHCOP00000023908	Uncharacterized protein. (105 aa)
	rad51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (338 aa)
	Gen1	Uncharacterized protein. (210 aa)
	smc5	Structural maintenance of chromosomes 5. (1177 aa)
	xrcc1	X-ray repair complementing defective repair in Chinese hamster cells 1. (612 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSHCOP00000023012	ENSHCOP00000023908	ENSHCOP00000023012	ENSHCOP00000023908	Uncharacterized protein.	Uncharacterized protein.	0.577
ENSHCOP00000023012	Gen1	ENSHCOP00000023012	ENSHCOP00000024625	Uncharacterized protein.	Uncharacterized protein.	0.662
ENSHCOP00000023012	ercc1	ENSHCOP00000023012	ENSHCOP00000014052	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.606
ENSHCOP00000023012	ercc4	ENSHCOP00000023012	ENSHCOP00000025158	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.608
ENSHCOP00000023012	msh2	ENSHCOP00000023012	ENSHCOP00000013100	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.730
ENSHCOP00000023012	msh3	ENSHCOP00000023012	ENSHCOP00000019337	Uncharacterized protein.	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.491
ENSHCOP00000023012	rad50	ENSHCOP00000023012	ENSHCOP00000018844	Uncharacterized protein.	RAD50 homolog, double strand break repair protein.	0.661
ENSHCOP00000023012	rad51	ENSHCOP00000023012	ENSHCOP00000024035	Uncharacterized protein.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.999
ENSHCOP00000023012	rad51c	ENSHCOP00000023012	ENSHCOP00000018579	Uncharacterized protein.	RAD51 paralog C.	0.971
ENSHCOP00000023012	rad51d	ENSHCOP00000023012	ENSHCOP00000007915	Uncharacterized protein.	RAD51 paralog D.	0.975
ENSHCOP00000023012	rad52	ENSHCOP00000023012	ENSHCOP00000023241	Uncharacterized protein.	RAD52 homolog, DNA repair protein.	0.702
ENSHCOP00000023012	smc5	ENSHCOP00000023012	ENSHCOP00000003098	Uncharacterized protein.	Structural maintenance of chromosomes 5.	0.468
ENSHCOP00000023012	smc6	ENSHCOP00000023012	ENSHCOP00000007176	Uncharacterized protein.	Si:dkey-119f1.1.	0.455
ENSHCOP00000023012	xrcc1	ENSHCOP00000023012	ENSHCOP00000004092	Uncharacterized protein.	X-ray repair complementing defective repair in Chinese hamster cells 1.	0.611
ENSHCOP00000023012	xrcc3	ENSHCOP00000023012	ENSHCOP00000006705	Uncharacterized protein.	DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.	0.967
ENSHCOP00000023908	ENSHCOP00000023012	ENSHCOP00000023908	ENSHCOP00000023012	Uncharacterized protein.	Uncharacterized protein.	0.577
ENSHCOP00000023908	Gen1	ENSHCOP00000023908	ENSHCOP00000024625	Uncharacterized protein.	Uncharacterized protein.	0.601
ENSHCOP00000023908	ercc1	ENSHCOP00000023908	ENSHCOP00000014052	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.757
ENSHCOP00000023908	ercc4	ENSHCOP00000023908	ENSHCOP00000025158	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.903
ENSHCOP00000023908	msh2	ENSHCOP00000023908	ENSHCOP00000013100	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.757