STRINGSTRING
smad6 smad6 tgfb2 tgfb2 LOC109513808 LOC109513808 skil skil LOC109512344 LOC109512344 LOC109531375 LOC109531375 LOC109515784 LOC109515784 LOC109523155 LOC109523155 ENSHCOP00000003601 ENSHCOP00000003601 LOC109525024 LOC109525024 smad1 smad1 appl2 appl2 cldn5 cldn5 smad2 smad2 ENSHCOP00000005461 ENSHCOP00000005461 LOC109517566 LOC109517566 TGFBR2 TGFBR2 LOC109515688 LOC109515688 LOC109520177 LOC109520177 tab1 tab1 ENSHCOP00000008393 ENSHCOP00000008393 Usp9x Usp9x smad3 smad3 LOC109517367 LOC109517367 LOC109528097 LOC109528097 ACVR1 ACVR1 bambi bambi LOC109532403 LOC109532403 LOC109522436 LOC109522436 LOC109515397 LOC109515397 LOC109514222 LOC109514222 LOC109530278 LOC109530278 appl1 appl1 ENSHCOP00000024654 ENSHCOP00000024654 tgfb3 tgfb3 nlk nlk smad7 smad7 LOC109514211 LOC109514211 LOC109518149 LOC109518149 ENSHCOP00000022714 ENSHCOP00000022714 SMAD3 SMAD3 LOC109507925 LOC109507925 smad9 smad9 ENSHCOP00000021691 ENSHCOP00000021691 LOC109514327 LOC109514327 ENSHCOP00000019306 ENSHCOP00000019306 ENSHCOP00000019285 ENSHCOP00000019285 LOC109511954 LOC109511954 flcn flcn itgb6 itgb6 cited1 cited1 fut8 fut8 LOC109514703 LOC109514703 LOC109510758 LOC109510758
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
smad6Mothers against decapentaplegic homolog. (481 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC109513808Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (476 aa)
skilSKI-like proto-oncogene a. (685 aa)
LOC109512344Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (787 aa)
LOC109531375Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (500 aa)
LOC109515784Mothers against decapentaplegic homolog. (477 aa)
LOC109523155Sirtuin 1. (657 aa)
ENSHCOP00000003601Uncharacterized protein. (472 aa)
LOC109525024Mothers against decapentaplegic homolog. (467 aa)
smad1Mothers against decapentaplegic homolog. (465 aa)
appl2Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (663 aa)
cldn5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (215 aa)
smad2Mothers against decapentaplegic homolog. (474 aa)
ENSHCOP00000005461Mothers against decapentaplegic homolog. (583 aa)
LOC109517566Myostatin b. (379 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (562 aa)
LOC109515688Leucine rich repeat containing 32. (707 aa)
LOC109520177Myostatin a. (367 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (494 aa)
ENSHCOP00000008393Integrin beta. (364 aa)
Usp9xUSP domain-containing protein; Belongs to the peptidase C19 family. (690 aa)
smad3Mothers against decapentaplegic homolog. (425 aa)
LOC109517367Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
LOC109528097JunE proto-oncogene, AP-1 transcription factor subunit. (344 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (671 aa)
bambiBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a. (306 aa)
LOC109532403Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (290 aa)
LOC109522436Growth differentiation factor 11. (379 aa)
LOC109515397Zyxin. (493 aa)
LOC109514222Negative regulator of reactive oxygen species. (678 aa)
LOC109530278TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (578 aa)
appl1Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1. (709 aa)
ENSHCOP00000024654Uncharacterized protein. (238 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (533 aa)
smad7Mothers against decapentaplegic homolog. (593 aa)
LOC109514211Mothers against decapentaplegic homolog. (510 aa)
LOC109518149Zgc:56585; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (264 aa)
ENSHCOP00000022714Uncharacterized protein. (276 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC109507925Golgi glycoprotein 1a. (1156 aa)
smad9Mothers against decapentaplegic homolog. (470 aa)
ENSHCOP00000021691Transforming growth factor, beta receptor III. (747 aa)
LOC109514327Uncharacterized protein. (1140 aa)
ENSHCOP00000019306Sirtuin 1. (369 aa)
ENSHCOP00000019285Deacetylase sirtuin-type domain-containing protein. (166 aa)
LOC109511954Transforming growth factor beta; Belongs to the TGF-beta family. (423 aa)
flcnFolliculin. (550 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (775 aa)
cited1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1. (168 aa)
fut8Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (583 aa)
LOC109514703Mothers against decapentaplegic homolog. (503 aa)
LOC109510758Transforming growth factor beta; Belongs to the TGF-beta family. (386 aa)
Your Current Organism:
Hippocampus comes
NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse
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