93 items (Hippocampus comes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rev1	REV1 DNA directed polymerase. (809 aa)
	ENSHCOP00000009932	Tripartite motif containing 32. (638 aa)
	eif2s1	Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
	LOC109512331	UmuC domain-containing protein. (184 aa)
	msh2	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (946 aa)
	cdkn2d	Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4). (162 aa)
	ube2a	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	ercc1	Excision repair cross-complementation group 1. (338 aa)
	ercc8	Excision repair cross-complementation group 8. (384 aa)
	ENSHCOP00000014556	Uncharacterized protein. (241 aa)
	aqp1	Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (259 aa)
	dcun1d3	DCN1-like protein. (326 aa)
	smpd1	Sphingomyelin phosphodiesterase 1, acid lysosomal. (510 aa)
	ddb1	Damage-specific DNA binding protein 1. (1093 aa)
	EIF2AK4	Eukaryotic translation initiation factor 2 alpha kinase 4. (1478 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (422 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (279 aa)
	LOC109527342	CREB binding protein a. (2447 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (749 aa)
	ino80	INO80 complex ATPase subunit. (1543 aa)
	tp53inp1	Tumor protein p53 inducible nuclear protein 1. (282 aa)
	ENSHCOP00000006047	Uncharacterized protein. (205 aa)
	msh6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1375 aa)
	ENSHCOP00000006772	Uncharacterized protein. (615 aa)
	LOC109532526	Uncharacterized protein. (1579 aa)
	ube2b	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	pclaf	PCNA clamp associated factor. (121 aa)
	LOC109523155	Sirtuin 1. (657 aa)
	LOC109510475	Mitogen-activated protein kinase. (360 aa)
	LOC109507207	Opsin 8, group member b; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (339 aa)
	ENSHCOP00000002506	BCL2 apoptosis regulator b. (225 aa)
	ENSHCOP00000018695	UV-stimulated scaffold protein A. (756 aa)
	ro60	Ro60, Y RNA binding protein. (545 aa)
	ENSHCOP00000019285	Deacetylase sirtuin-type domain-containing protein. (166 aa)
	ENSHCOP00000019306	Sirtuin 1. (369 aa)
	usp1	Ubiquitin carboxyl-terminal hydrolase. (771 aa)
	LOC109515948	Aurora kinase B; Belongs to the protein kinase superfamily. (330 aa)
	LOC109508060	Zgc:153993. (204 aa)
	LOC109532549	CREB binding protein b. (1735 aa)
	ppid	Peptidylprolyl isomerase D. (375 aa)
	ENSHCOP00000023012	Uncharacterized protein. (1155 aa)
	parp1	Poly [ADP-ribose] polymerase. (1020 aa)
	usf1	Upstream transcription factor 1. (299 aa)
	map3k4	Mitogen-activated protein kinase kinase kinase 4. (1500 aa)
	zranb3	Zinc finger, RAN-binding domain containing 3. (1127 aa)
	LOC109524680	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
	LOC109514850	E1A binding protein p300 b. (2669 aa)
	pold1	DNA polymerase. (1105 aa)
	Atr	Uncharacterized protein. (106 aa)
	ercc4	Excision repair cross-complementation group 4. (900 aa)
	LOC109526648	Mitogen-activated protein kinase. (354 aa)
	ube4b	Ubiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1184 aa)
	Mc1r	Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (322 aa)
	impact	Impact RWD domain protein. (312 aa)
	bax	BCL2 associated X, apoptosis regulator a. (255 aa)
	polh	Polymerase (DNA directed), eta. (483 aa)
	bmf	Bcl2 modifying factor. (135 aa)
	ENSHCOP00000027148	RWD domain-containing protein. (198 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (462 aa)
	rhbdd1	Rhomboid domain containing 1. (328 aa)
	ercc6	Excision repair cross-complementation group 6. (1377 aa)
	primpol	Primase and polymerase (DNA-directed). (501 aa)
	stk11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (430 aa)
	sirt6	Sirtuin 6. (347 aa)
	LOC109512841	E1A binding protein p300 a. (2561 aa)
	men1	Multiple endocrine neoplasia I. (611 aa)
	pold3	Polymerase (DNA-directed), delta 3, accessory subunit. (437 aa)
	cops9	COP9 signalosome subunit 9. (57 aa)
	tmem161a	Transmembrane protein 161A. (487 aa)
	il12b	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (355 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1363 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (575 aa)
	Ercc5	XPGI domain-containing protein. (373 aa)
	sprtn	SprT-like N-terminal domain. (405 aa)
	kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (839 aa)
	LOC109524107	Nuclear factor of activated T cells 4. (805 aa)
	bivm	Basic, immunoglobulin-like variable motif containing. (472 aa)
	opn3	Opsin 3. (385 aa)
	noc2l	NOC2-like nucleolar associated transcriptional repressor. (760 aa)
	dtl	Denticleless E3 ubiquitin protein ligase homolog (Drosophila). (616 aa)
	ENSHCOP00000002291	XPGN domain-containing protein. (242 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (477 aa)
	ENSHCOP00000002481	BCL2 apoptosis regulator b. (221 aa)
	Polk	Polymerase (DNA directed) kappa. (396 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (772 aa)
	ddb2	Damage-specific DNA binding protein 2. (489 aa)
	ercc2	Excision repair cross-complementation group 2. (591 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (859 aa)
	zbtb1	Zinc finger and BTB domain containing 1. (626 aa)
	LOC109531756	Opsin 5; Belongs to the G-protein coupled receptor 1 family. (334 aa)
	LOC109522222	Mitogen-activated protein kinase. (449 aa)
	actr5	Actin related protein 5; Belongs to the actin family. (595 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (966 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Atr	ENSHCOP00000002291	ENSHCOP00000025135	ENSHCOP00000002291	Uncharacterized protein.	XPGN domain-containing protein.	0.713
Atr	ENSHCOP00000014556	ENSHCOP00000025135	ENSHCOP00000014556	Uncharacterized protein.	Uncharacterized protein.	0.639
Atr	ENSHCOP00000023012	ENSHCOP00000025135	ENSHCOP00000023012	Uncharacterized protein.	Uncharacterized protein.	0.611
Atr	Ercc5	ENSHCOP00000025135	ENSHCOP00000002276	Uncharacterized protein.	XPGI domain-containing protein.	0.713
Atr	LOC109524680	ENSHCOP00000025135	ENSHCOP00000024300	Uncharacterized protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.514
Atr	bivm	ENSHCOP00000025135	ENSHCOP00000011028	Uncharacterized protein.	Basic, immunoglobulin-like variable motif containing.	0.713
Atr	chek1	ENSHCOP00000025135	ENSHCOP00000027175	Uncharacterized protein.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.998
Atr	ercc1	ENSHCOP00000025135	ENSHCOP00000014052	Uncharacterized protein.	Excision repair cross-complementation group 1.	0.721
Atr	ercc2	ENSHCOP00000025135	ENSHCOP00000012363	Uncharacterized protein.	Excision repair cross-complementation group 2.	0.823
Atr	ercc4	ENSHCOP00000025135	ENSHCOP00000025158	Uncharacterized protein.	Excision repair cross-complementation group 4.	0.826
Atr	ercc6	ENSHCOP00000025135	ENSHCOP00000027896	Uncharacterized protein.	Excision repair cross-complementation group 6.	0.558
Atr	msh2	ENSHCOP00000025135	ENSHCOP00000013100	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.771
Atr	msh6	ENSHCOP00000025135	ENSHCOP00000010111	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.857
Atr	pold1	ENSHCOP00000025135	ENSHCOP00000024706	Uncharacterized protein.	DNA polymerase.	0.494
Atr	rev1	ENSHCOP00000025135	ENSHCOP00000002495	Uncharacterized protein.	REV1 DNA directed polymerase.	0.541
Atr	ube2a	ENSHCOP00000025135	ENSHCOP00000013849	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.514
Atr	ube2b	ENSHCOP00000025135	ENSHCOP00000006296	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.	0.514
Atr	xpa	ENSHCOP00000025135	ENSHCOP00000016946	Uncharacterized protein.	Xeroderma pigmentosum, complementation group A.	0.581
Atr	xpc	ENSHCOP00000025135	ENSHCOP00000005278	Uncharacterized protein.	Xeroderma pigmentosum, complementation group C.	0.667
EIF2AK4	ENSHCOP00000027148	ENSHCOP00000015164	ENSHCOP00000027148	Eukaryotic translation initiation factor 2 alpha kinase 4.	RWD domain-containing protein.	0.891