(26 nodes) Regulation of necrotic cell death network (Hippocampus comes)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	casp6	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (288 aa)
	asah1	N-acylsphingosine amidohydrolase (acid ceramidase) 1a; Belongs to the acid ceramidase family. (391 aa)
	FADD	Fas associated via death domain. (188 aa)
	LOC109523106	Uncharacterized protein. (202 aa)
	LOC109518471	Uncharacterized protein. (767 aa)
	MUTYH	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (526 aa)
	spata2	Spermatogenesis associated 2. (568 aa)
	LOC109509327	Uncharacterized protein. (154 aa)
	LOC109521190	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (806 aa)
	ENSHCOP00000027903	annotation not available (76 aa)
	ripk1	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (677 aa)
	atg9a	Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (853 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (771 aa)
	nupr1	Nuclear protein 1b. (74 aa)
	LOC109516522	Uncharacterized protein. (727 aa)
	LOC109520533	Uncharacterized protein; Belongs to the peptidase C14A family. (492 aa)
	LOC109511045	Heme-binding protein soul5, like. (373 aa)
	LOC109521498	Cylindromatosis (turban tumor syndrome), b. (711 aa)
	adprhl2	ADP-ribosylhydrolase like 2. (380 aa)
	LOC109524061	Uncharacterized protein. (935 aa)
	LOC109518096	Heme binding protein 2. (194 aa)
	Ucn	CRF domain-containing protein. (134 aa)
	LOC109509211	Heme-binding protein soul5. (220 aa)
	rbck1	RanBP-type and C3HC4-type zinc finger containing 1. (504 aa)
	cflar	Uncharacterized protein; Belongs to the peptidase C14A family. (480 aa)
	ENSHCOP00000016349	Nuclear protein 1a. (76 aa)

Your Current Organism:

Hippocampus comes

NCBI taxonomy Id: 109280
Other names: H. comes, tiger tail seahorse

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADD	LOC109509327	ENSHCOP00000020973	ENSHCOP00000027742	Fas associated via death domain.	Uncharacterized protein.	0.969
FADD	LOC109516522	ENSHCOP00000020973	ENSHCOP00000001527	Fas associated via death domain.	Uncharacterized protein.	0.625
FADD	LOC109520533	ENSHCOP00000020973	ENSHCOP00000001852	Fas associated via death domain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.997
FADD	LOC109521498	ENSHCOP00000020973	ENSHCOP00000002314	Fas associated via death domain.	Cylindromatosis (turban tumor syndrome), b.	0.664
FADD	casp6	ENSHCOP00000020973	ENSHCOP00000019235	Fas associated via death domain.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.561
FADD	cflar	ENSHCOP00000020973	ENSHCOP00000014172	Fas associated via death domain.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.962
FADD	cyld	ENSHCOP00000020973	ENSHCOP00000000209	Fas associated via death domain.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.664
FADD	ripk1	ENSHCOP00000020973	ENSHCOP00000028031	Fas associated via death domain.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.998
LOC109509327	FADD	ENSHCOP00000027742	ENSHCOP00000020973	Uncharacterized protein.	Fas associated via death domain.	0.969
LOC109509327	casp6	ENSHCOP00000027742	ENSHCOP00000019235	Uncharacterized protein.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.703
LOC109509327	cflar	ENSHCOP00000027742	ENSHCOP00000014172	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.955
LOC109509327	ripk1	ENSHCOP00000027742	ENSHCOP00000028031	Uncharacterized protein.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.965
LOC109516522	FADD	ENSHCOP00000001527	ENSHCOP00000020973	Uncharacterized protein.	Fas associated via death domain.	0.625
LOC109516522	LOC109518471	ENSHCOP00000001527	ENSHCOP00000021443	Uncharacterized protein.	Uncharacterized protein.	0.802
LOC109516522	LOC109520533	ENSHCOP00000001527	ENSHCOP00000001852	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.919
LOC109516522	LOC109521498	ENSHCOP00000001527	ENSHCOP00000002314	Uncharacterized protein.	Cylindromatosis (turban tumor syndrome), b.	0.908
LOC109516522	LOC109524061	ENSHCOP00000001527	ENSHCOP00000009013	Uncharacterized protein.	Uncharacterized protein.	0.802
LOC109516522	rbck1	ENSHCOP00000001527	ENSHCOP00000011175	Uncharacterized protein.	RanBP-type and C3HC4-type zinc finger containing 1.	0.510
LOC109516522	ripk1	ENSHCOP00000001527	ENSHCOP00000028031	Uncharacterized protein.	Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.	0.980
LOC109516522	spata2	ENSHCOP00000001527	ENSHCOP00000023264	Uncharacterized protein.	Spermatogenesis associated 2.	0.951